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Erschienen in: The European Journal of Health Economics 6/2018

19.08.2017 | Original Paper

Guidelines versus reality: is coronary stent application in three-vessel disease standard or the exception?

verfasst von: Roland Linder, J. Zeidler, F. Verheyen, J.-M. Graf von der Schulenburg, A. Haverich, T. Schilling

Erschienen in: The European Journal of Health Economics | Ausgabe 6/2018

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Abstract

The national guidelines for treatment of chronic coronary heart disease (CHD) recommend surgical coronary aortic bypass grafting (CABG) rather than percutaneous coronary intervention (PCI) for patients with a coronary three-vessel disease. The epidemiology of three-vessel CHD and data about the application of different revascularisation strategies raise suspicion of deviation from the guidelines in the treatment of those patients. Claims data containing records of almost 10 million patients of the largest German statutory health insurance fund (Techniker Krankenkasse) were utilised to measure adherence to the guidelines for treatment of groups of patients with one-, two-, and three-vessel CHD, respectively. The impact of age, sex, and comorbidity on each patient’s revascularisation procedure was investigated as well. There was no significant difference in the rate of PCI between the groups. In conclusion, the hypothesis that patients with a coronary three-vessel disease are not always treated according to the recommendations of the national guidelines could not be disproved by this study. Finally, the results of this study suggest that the best revascularisation strategy for each patient with two- and three-vessel disease should be decided upon by an interdisciplinary discussion between both cardiologists and cardiac surgeons.
Literatur
1.
Zurück zum Zitat Benedetto, U., Gaudino, M., Ng, C., Biondi-Zoccai, G., D’Ascenzo, F., Frati, G., Girardi, L.N., Angelini, G.D., Taggart, D.P.: Coronary surgery is superior to drug eluting stents in multivessel disease. Systematic review and meta-analysis of contemporary randomized controlled trials. Int. J. Cardiol. 210, 19–24 (2016). doi: 10.​1016/​j.​ijcard.​2016.​02.​090 CrossRefPubMed Benedetto, U., Gaudino, M., Ng, C., Biondi-Zoccai, G., D’Ascenzo, F., Frati, G., Girardi, L.N., Angelini, G.D., Taggart, D.P.: Coronary surgery is superior to drug eluting stents in multivessel disease. Systematic review and meta-analysis of contemporary randomized controlled trials. Int. J. Cardiol. 210, 19–24 (2016). doi: 10.​1016/​j.​ijcard.​2016.​02.​090 CrossRefPubMed
2.
Zurück zum Zitat Mohr, F.W., Morice, M.C., Kappetein, A.P., Feldman, T.E., Stahle, E., Colombo, A., Mack, M.J., Holmes Jr., D.R., Morel, M.A., van Dyck, N., Houle, V.M., Dawkins, K.D., Serruys, P.W.: Coronary artery bypass graft surgery versus percutaneous coronary intervention in patients with three-vessel disease and left main coronary disease: 5-year follow-up of the randomised, clinical SYNTAX trial. Lancet 381(9867), 629–638 (2013) CrossRefPubMed Mohr, F.W., Morice, M.C., Kappetein, A.P., Feldman, T.E., Stahle, E., Colombo, A., Mack, M.J., Holmes Jr., D.R., Morel, M.A., van Dyck, N., Houle, V.M., Dawkins, K.D., Serruys, P.W.: Coronary artery bypass graft surgery versus percutaneous coronary intervention in patients with three-vessel disease and left main coronary disease: 5-year follow-up of the randomised, clinical SYNTAX trial. Lancet 381(9867), 629–638 (2013) CrossRefPubMed
3.
Zurück zum Zitat Weintraub, W.S., Grau-Sepulveda, M.V., Weiss, J.M., O’Brien, S.M., Peterson, E.D., Kolm, P., Zhang, Z., Klein, L.W., Shaw, R.E., McKay, C., Ritzenthaler, L.L., Popma, J.J., Messenger, J.C., Shahian, D.M., Grover, F.L., Mayer, J.E., Shewan, C.M., Garratt, K.N., Moussa, I.D., Dangas, G.D., Edwards, F.H.: Comparative effectiveness of revascularization strategies. N. Engl. J. Med. 366(16), 1467–1476 (2012) CrossRefPubMedPubMedCentral Weintraub, W.S., Grau-Sepulveda, M.V., Weiss, J.M., O’Brien, S.M., Peterson, E.D., Kolm, P., Zhang, Z., Klein, L.W., Shaw, R.E., McKay, C., Ritzenthaler, L.L., Popma, J.J., Messenger, J.C., Shahian, D.M., Grover, F.L., Mayer, J.E., Shewan, C.M., Garratt, K.N., Moussa, I.D., Dangas, G.D., Edwards, F.H.: Comparative effectiveness of revascularization strategies. N. Engl. J. Med. 366(16), 1467–1476 (2012) CrossRefPubMedPubMedCentral
4.
Zurück zum Zitat Kappetein, A.P., Feldman, T.E., Mack, M.J., Morice, M.C., Holmes, D.R., Stahle, E., Dawkins, K.D., Mohr, F.W., Serruys, P.W., Colombo, A.: Comparison of coronary bypass surgery with drug-eluting stenting for the treatment of left main and/or three-vessel disease: 3-year follow-up of the SYNTAX trial. Eur. Heart J. 32(17), 2125–2134 (2011) CrossRefPubMed Kappetein, A.P., Feldman, T.E., Mack, M.J., Morice, M.C., Holmes, D.R., Stahle, E., Dawkins, K.D., Mohr, F.W., Serruys, P.W., Colombo, A.: Comparison of coronary bypass surgery with drug-eluting stenting for the treatment of left main and/or three-vessel disease: 3-year follow-up of the SYNTAX trial. Eur. Heart J. 32(17), 2125–2134 (2011) CrossRefPubMed
5.
Zurück zum Zitat Serruys, P.W., Morice, M.C., Kappetein, A.P., Colombo, A., Holmes, D.R., Mack, M.J., Stahle, E., Feldman, T.E., van den Brand, M., Bass, E.J., Van, D.N., Leadley, K., Dawkins, K.D., Mohr, F.W.: Percutaneous coronary intervention versus coronary-artery bypass grafting for severe coronary artery disease. N. Engl. J. Med. 360(10), 961–972 (2009) CrossRefPubMed Serruys, P.W., Morice, M.C., Kappetein, A.P., Colombo, A., Holmes, D.R., Mack, M.J., Stahle, E., Feldman, T.E., van den Brand, M., Bass, E.J., Van, D.N., Leadley, K., Dawkins, K.D., Mohr, F.W.: Percutaneous coronary intervention versus coronary-artery bypass grafting for severe coronary artery disease. N. Engl. J. Med. 360(10), 961–972 (2009) CrossRefPubMed
6.
Zurück zum Zitat Authors/Task Force, m, Windecker, S., Kolh, P., Alfonso, F., Collet, J.P., Cremer, J., Falk, V., Filippatos, G., Hamm, C., Head, S.J., Juni, P., Kappetein, A.P., Kastrati, A., Knuuti, J., Landmesser, U., Laufer, G., Neumann, F.J., Richter, D.J., Schauerte, P., Sousa Uva, M., Stefanini, G.G., Taggart, D.P., Torracca, L., Valgimigli, M., Wijns, W., Witkowski, A.: 2014 ESC/EACTS guidelines on myocardial revascularization: The Task Force on Myocardial Revascularization of the European Society of Cardiology (ESC) and the European Association for Cardio-Thoracic Surgery (EACTS) developed with the special contribution of the European Association of Percutaneous Cardiovascular Interventions (EAPCI). Eur. Heart J. 35(37), 2541–2619 (2014). doi: 10.​1093/​eurheartj/​ehu278 CrossRef Authors/Task Force, m, Windecker, S., Kolh, P., Alfonso, F., Collet, J.P., Cremer, J., Falk, V., Filippatos, G., Hamm, C., Head, S.J., Juni, P., Kappetein, A.P., Kastrati, A., Knuuti, J., Landmesser, U., Laufer, G., Neumann, F.J., Richter, D.J., Schauerte, P., Sousa Uva, M., Stefanini, G.G., Taggart, D.P., Torracca, L., Valgimigli, M., Wijns, W., Witkowski, A.: 2014 ESC/EACTS guidelines on myocardial revascularization: The Task Force on Myocardial Revascularization of the European Society of Cardiology (ESC) and the European Association for Cardio-Thoracic Surgery (EACTS) developed with the special contribution of the European Association of Percutaneous Cardiovascular Interventions (EAPCI). Eur. Heart J. 35(37), 2541–2619 (2014). doi: 10.​1093/​eurheartj/​ehu278 CrossRef
7.
Zurück zum Zitat Biancari, F., Myllyl, M., Lepojrvi, S., Kuttila, K., Porela, P., Laitio, T., Ylitalo, A., Jokinen, V., Luokkala, A., Airaksinen, K.E.: Preoperative warfarin treatment and outcome of coronary artery bypass graft surgery. Ann. Thorac. Surg. 89(4), 1139–1145 (2010) CrossRefPubMed Biancari, F., Myllyl, M., Lepojrvi, S., Kuttila, K., Porela, P., Laitio, T., Ylitalo, A., Jokinen, V., Luokkala, A., Airaksinen, K.E.: Preoperative warfarin treatment and outcome of coronary artery bypass graft surgery. Ann. Thorac. Surg. 89(4), 1139–1145 (2010) CrossRefPubMed
8.
Zurück zum Zitat Cohen, D.J., Lavelle, T.A., Van Hout, B., Li, H., Lei, Y., Robertus, K., Pinto, D., Magnuson, E.A., McGarry, T.F., Lucas, S.K., Horwitz, P.A., Henry, C.A., Serruys, P.W., Mohr, F.W., Kappetein, A.P.: Economic outcomes of percutaneous coronary intervention with drug-eluting stents versus bypass surgery for patients with left main or three-vessel coronary artery disease: one-year results from the SYNTAX trial. Catheter. Cardiovasc. Interv. 79(2), 198–209 (2012) CrossRefPubMed Cohen, D.J., Lavelle, T.A., Van Hout, B., Li, H., Lei, Y., Robertus, K., Pinto, D., Magnuson, E.A., McGarry, T.F., Lucas, S.K., Horwitz, P.A., Henry, C.A., Serruys, P.W., Mohr, F.W., Kappetein, A.P.: Economic outcomes of percutaneous coronary intervention with drug-eluting stents versus bypass surgery for patients with left main or three-vessel coronary artery disease: one-year results from the SYNTAX trial. Catheter. Cardiovasc. Interv. 79(2), 198–209 (2012) CrossRefPubMed
9.
Zurück zum Zitat Serruys, P.W., Unger, F., Sousa, J.E., Jatene, A., Bonnier, H.J., Schonberger, J.P., Buller, N., Bonser, R., van den Brand, M.J., van Herwerden, L.A., Morel, M.A., van Hout, B.A.: Comparison of coronary-artery bypass surgery and stenting for the treatment of multivessel disease. N. Engl. J. Med. 344(15), 1117–1124 (2001) CrossRefPubMed Serruys, P.W., Unger, F., Sousa, J.E., Jatene, A., Bonnier, H.J., Schonberger, J.P., Buller, N., Bonser, R., van den Brand, M.J., van Herwerden, L.A., Morel, M.A., van Hout, B.A.: Comparison of coronary-artery bypass surgery and stenting for the treatment of multivessel disease. N. Engl. J. Med. 344(15), 1117–1124 (2001) CrossRefPubMed
10.
Zurück zum Zitat Bundesärztekammer, Kassenärztliche, B., Arbeitsgemeinschaft der Wissenschaftlichen Medizinischen, F.: Nationale VersorgungsLeitlinie Chronische KHK—Langfassung, vol. 2. Aerztliches Zentrum fuer Qualitaet in der Medizin, Berlin (2013) Bundesärztekammer, Kassenärztliche, B., Arbeitsgemeinschaft der Wissenschaftlichen Medizinischen, F.: Nationale VersorgungsLeitlinie Chronische KHK—Langfassung, vol. 2. Aerztliches Zentrum fuer Qualitaet in der Medizin, Berlin (2013)
11.
Zurück zum Zitat Beckmann, A., Funkat, A.K., Lewandowski, J., Frie, M., Schiller, W., Hekmat, K., Gummert, J.F., Mohr, F.W.: Cardiac surgery in Germany during 2012: a report on behalf of the German Society for Thoracic and Cardiovascular Surgery. Thorac. Cardiovasc. Surg. 62(1), 5–17 (2014) PubMed Beckmann, A., Funkat, A.K., Lewandowski, J., Frie, M., Schiller, W., Hekmat, K., Gummert, J.F., Mohr, F.W.: Cardiac surgery in Germany during 2012: a report on behalf of the German Society for Thoracic and Cardiovascular Surgery. Thorac. Cardiovasc. Surg. 62(1), 5–17 (2014) PubMed
12.
Zurück zum Zitat Bruckenberger, E.: Multidisciplinary health report on cardiology and cardiac surgery, vol. 25. Deutsche Herzstiftung, Hannover (2013) Bruckenberger, E.: Multidisciplinary health report on cardiology and cardiac surgery, vol. 25. Deutsche Herzstiftung, Hannover (2013)
13.
Zurück zum Zitat Kimura, T., Morimoto, T., Furukawa, Y., Nakagawa, Y., Kadota, K., Iwabuchi, M., Shizuta, S., Shiomi, H., Tada, T., Tazaki, J., Kato, Y., Hayano, M., Abe, M., Tamura, T., Shirotani, M., Miki, S., Matsuda, M., Takahashi, M., Ishii, K., Tanaka, M., Aoyama, T., Doi, O., Hattori, R., Tatami, R., Suwa, S., Takizawa, A., Takatsu, Y., Takahashi, M., Kato, H., Takeda, T., Lee, J.D., Nohara, R., Ogawa, H., Tei, C., Horie, M., Kambara, H., Fujiwara, H., Mitsudo, K., Nobuyoshi, M., Kita, T.: Long-term safety and efficacy of sirolimus-eluting stents versus bare-metal stents in real world clinical practice in Japan. Cardiovasc. Interv. Ther. 26(3), 234–245 (2011) CrossRefPubMed Kimura, T., Morimoto, T., Furukawa, Y., Nakagawa, Y., Kadota, K., Iwabuchi, M., Shizuta, S., Shiomi, H., Tada, T., Tazaki, J., Kato, Y., Hayano, M., Abe, M., Tamura, T., Shirotani, M., Miki, S., Matsuda, M., Takahashi, M., Ishii, K., Tanaka, M., Aoyama, T., Doi, O., Hattori, R., Tatami, R., Suwa, S., Takizawa, A., Takatsu, Y., Takahashi, M., Kato, H., Takeda, T., Lee, J.D., Nohara, R., Ogawa, H., Tei, C., Horie, M., Kambara, H., Fujiwara, H., Mitsudo, K., Nobuyoshi, M., Kita, T.: Long-term safety and efficacy of sirolimus-eluting stents versus bare-metal stents in real world clinical practice in Japan. Cardiovasc. Interv. Ther. 26(3), 234–245 (2011) CrossRefPubMed
14.
Zurück zum Zitat Schilling, T., Haverich, A.: The contradictory contexts of interdisciplinarity. Chirurg 83(4), 332–338 (2012) CrossRefPubMed Schilling, T., Haverich, A.: The contradictory contexts of interdisciplinarity. Chirurg 83(4), 332–338 (2012) CrossRefPubMed
15.
Zurück zum Zitat Morice, M.C., Serruys, P.W., Kappetein, A.P., Feldman, T.E., Stahle, E., Colombo, A., Mack, M.J., Holmes, D.R., Choi, J.W., Ruzyllo, W., Religa, G., Huang, J., Roy, K., Dawkins, K.D., Mohr, F.: Five-year outcomes in patients with left main disease treated with either percutaneous coronary intervention or coronary artery bypass grafting in the SYNTAX trial. Circulation 129(23), 2388–2394 (2014) CrossRefPubMed Morice, M.C., Serruys, P.W., Kappetein, A.P., Feldman, T.E., Stahle, E., Colombo, A., Mack, M.J., Holmes, D.R., Choi, J.W., Ruzyllo, W., Religa, G., Huang, J., Roy, K., Dawkins, K.D., Mohr, F.: Five-year outcomes in patients with left main disease treated with either percutaneous coronary intervention or coronary artery bypass grafting in the SYNTAX trial. Circulation 129(23), 2388–2394 (2014) CrossRefPubMed
16.
Zurück zum Zitat Statistisches, B.: Bevoelkerung und Erwerbstaetigkeit. Bev”lkerungsfortschreibung. Statistisches Bundesamt, Wiesbaden (2013) Statistisches, B.: Bevoelkerung und Erwerbstaetigkeit. Bev”lkerungsfortschreibung. Statistisches Bundesamt, Wiesbaden (2013)
17.
Zurück zum Zitat Elixhauser, A., Steiner, C., Harris, D.R., Coffey, R.M.: Comorbidity measures for use with administrative data. Med. Care 36(1), 8–27 (1998) CrossRefPubMed Elixhauser, A., Steiner, C., Harris, D.R., Coffey, R.M.: Comorbidity measures for use with administrative data. Med. Care 36(1), 8–27 (1998) CrossRefPubMed
18.
Zurück zum Zitat Quan, H., Sundararajan, V., Halfon, P., Fong, A., Burnand, B., Luthi, J.C., Saunders, L.D., Beck, C.A., Feasby, T.E., Ghali, W.A.: Coding algorithms for defining comorbidities in ICD-9-CM and ICD-10 administrative data. Med. Care 43(11), 1130–1139 (2005) CrossRefPubMed Quan, H., Sundararajan, V., Halfon, P., Fong, A., Burnand, B., Luthi, J.C., Saunders, L.D., Beck, C.A., Feasby, T.E., Ghali, W.A.: Coding algorithms for defining comorbidities in ICD-9-CM and ICD-10 administrative data. Med. Care 43(11), 1130–1139 (2005) CrossRefPubMed
19.
Zurück zum Zitat van Walraven, C., Austin, P.C., Jennings, A., Quan, H., Forster, A.J.: A modification of the Elixhauser comorbidity measures into a point system for hospital death using administrative data. Med. Care 47(6), 626–633 (2009) CrossRefPubMed van Walraven, C., Austin, P.C., Jennings, A., Quan, H., Forster, A.J.: A modification of the Elixhauser comorbidity measures into a point system for hospital death using administrative data. Med. Care 47(6), 626–633 (2009) CrossRefPubMed
20.
Zurück zum Zitat Kappetein, A.P., Head, S.J., Morice, M.C., Banning, A.P., Serruys, P.W., Mohr, F.W., Dawkins, K.D., Mack, M.J.: Treatment of complex coronary artery disease in patients with diabetes: 5-year results comparing outcomes of bypass surgery and percutaneous coronary intervention in the SYNTAX trial. Eur. J. Cardiothorac. Surg. 43(5), 1006–1013 (2013) CrossRefPubMed Kappetein, A.P., Head, S.J., Morice, M.C., Banning, A.P., Serruys, P.W., Mohr, F.W., Dawkins, K.D., Mack, M.J.: Treatment of complex coronary artery disease in patients with diabetes: 5-year results comparing outcomes of bypass surgery and percutaneous coronary intervention in the SYNTAX trial. Eur. J. Cardiothorac. Surg. 43(5), 1006–1013 (2013) CrossRefPubMed
21.
Zurück zum Zitat Serruys, P.W., Ong, A.T., van Herwerden, L.A., Sousa, J.E., Jatene, A., Bonnier, J.J., Schonberger, J.P., Buller, N., Bonser, R., Disco, C., Backx, B., Hugenholtz, P.G., Firth, B.G., Unger, F.: Five-year outcomes after coronary stenting versus bypass surgery for the treatment of multivessel disease: the final analysis of the Arterial Revascularization Therapies Study (ARTS) randomized trial. J. Am. Coll. Cardiol. 46(4), 575–581 (2005) CrossRefPubMed Serruys, P.W., Ong, A.T., van Herwerden, L.A., Sousa, J.E., Jatene, A., Bonnier, J.J., Schonberger, J.P., Buller, N., Bonser, R., Disco, C., Backx, B., Hugenholtz, P.G., Firth, B.G., Unger, F.: Five-year outcomes after coronary stenting versus bypass surgery for the treatment of multivessel disease: the final analysis of the Arterial Revascularization Therapies Study (ARTS) randomized trial. J. Am. Coll. Cardiol. 46(4), 575–581 (2005) CrossRefPubMed
22.
Zurück zum Zitat Tazaki, J., Shiomi, H., Morimoto, T., Imai, M., Yamaji, K., Sakata, R., Okabayashi, H., Hanyu, M., Shimamoto, M., Nishiwaki, N., Komiya, T., Kimura, T.: Three-year outcome after percutaneous coronary intervention and coronary artery bypass grafting in patients with triple-vessel coronary artery disease: observations from the CREDO-Kyoto PCI/CABG registry cohort-2. EuroIntervention 9(4), 437–445 (2013) CrossRefPubMed Tazaki, J., Shiomi, H., Morimoto, T., Imai, M., Yamaji, K., Sakata, R., Okabayashi, H., Hanyu, M., Shimamoto, M., Nishiwaki, N., Komiya, T., Kimura, T.: Three-year outcome after percutaneous coronary intervention and coronary artery bypass grafting in patients with triple-vessel coronary artery disease: observations from the CREDO-Kyoto PCI/CABG registry cohort-2. EuroIntervention 9(4), 437–445 (2013) CrossRefPubMed
23.
Zurück zum Zitat Thiem, A., Attmann, T., Cremer, J.: Moderne Koronarchirurgie in Zusammenhang mit der SYNTAX-Studie und aktuellen Leitlinien. Herz 36(8), 669–676 (2011) CrossRefPubMed Thiem, A., Attmann, T., Cremer, J.: Moderne Koronarchirurgie in Zusammenhang mit der SYNTAX-Studie und aktuellen Leitlinien. Herz 36(8), 669–676 (2011) CrossRefPubMed
24.
Zurück zum Zitat Maier, W., Camici, P., Windecker, S., Pfiffner, D., Wijns, W., Meier, B.: The European registry of cardiac catheter interventions 1997. Eur. Heart J. 23(24), 1903–1907 (2002) CrossRefPubMed Maier, W., Camici, P., Windecker, S., Pfiffner, D., Wijns, W., Meier, B.: The European registry of cardiac catheter interventions 1997. Eur. Heart J. 23(24), 1903–1907 (2002) CrossRefPubMed
25.
Zurück zum Zitat van Buuren, F., Horstkotte, D.: 24th report about the statistics of the heart catheterization laboratory in the German Federal Republic. Results of the joint inquiry of the Commission for Clinical Cardiology and of the Working Groups for Interventional Cardiology and Angiology of the German Society for Cardiology and Circulatory Research in the year 2007. Kardiologie 3, 512–518 (2009) CrossRef van Buuren, F., Horstkotte, D.: 24th report about the statistics of the heart catheterization laboratory in the German Federal Republic. Results of the joint inquiry of the Commission for Clinical Cardiology and of the Working Groups for Interventional Cardiology and Angiology of the German Society for Cardiology and Circulatory Research in the year 2007. Kardiologie 3, 512–518 (2009) CrossRef
26.
Zurück zum Zitat Hoffmann, F., Icks, A.: Unterschiede in der Versichertenstruktur von Krankenkassen und deren Auswirkungen für die Versorgungsforschung: Ergebnisse des Bertelsmann-Gesundheitsmonitors. Gesundheitswesen 74(5), 291–297 (2012) CrossRefPubMed Hoffmann, F., Icks, A.: Unterschiede in der Versichertenstruktur von Krankenkassen und deren Auswirkungen für die Versorgungsforschung: Ergebnisse des Bertelsmann-Gesundheitsmonitors. Gesundheitswesen 74(5), 291–297 (2012) CrossRefPubMed
27.
Zurück zum Zitat Go, A.S., Mozaffarian, D., Roger, V.L., Benjamin, E.J., Berry, J.D., Borden, W.B., Bravata, D.M., Dai, S., Ford, E.S., Fox, C.S., Franco, S., Fullerton, H.J., Gillespie, C., Hailpern, S.M., Heit, J.A., Howard, V.J., Huffman, M.D., Kissela, B.M., Kittner, S.J., Lackland, D.T., Lichtman, J.H., Lisabeth, L.D., Magid, D., Marcus, G.M., Marelli, A., Matchar, D.B., McGuire, D.K., Mohler, E.R., Moy, C.S., Mussolino, M.E., Nichol, G., Paynter, N.P., Schreiner, P.J., Sorlie, P.D., Stein, J., Turan, T.N., Virani, S.S., Wong, N.D., Woo, D., Turner, M.B.: Heart disease and stroke statistics–2013 update: a report from the American Heart Association. Circulation 127(1), e6–e245 (2013) CrossRefPubMed Go, A.S., Mozaffarian, D., Roger, V.L., Benjamin, E.J., Berry, J.D., Borden, W.B., Bravata, D.M., Dai, S., Ford, E.S., Fox, C.S., Franco, S., Fullerton, H.J., Gillespie, C., Hailpern, S.M., Heit, J.A., Howard, V.J., Huffman, M.D., Kissela, B.M., Kittner, S.J., Lackland, D.T., Lichtman, J.H., Lisabeth, L.D., Magid, D., Marcus, G.M., Marelli, A., Matchar, D.B., McGuire, D.K., Mohler, E.R., Moy, C.S., Mussolino, M.E., Nichol, G., Paynter, N.P., Schreiner, P.J., Sorlie, P.D., Stein, J., Turan, T.N., Virani, S.S., Wong, N.D., Woo, D., Turner, M.B.: Heart disease and stroke statistics–2013 update: a report from the American Heart Association. Circulation 127(1), e6–e245 (2013) CrossRefPubMed
28.
Zurück zum Zitat Lange, C.: Daten und Fakten: Ergebnisse der Studie “Gesundheit in Deutschland aktuell 2010”. Berlin (2012) Lange, C.: Daten und Fakten: Ergebnisse der Studie “Gesundheit in Deutschland aktuell 2010”. Berlin (2012)
29.
Zurück zum Zitat Farkouh, M.E., Domanski, M., Sleeper, L.A., Siami, F.S., Dangas, G., Mack, M., Yang, M., Cohen, D.J., Rosenberg, Y., Solomon, S.D., Desai, A.S., Gersh, B.J., Magnuson, E.A., Lansky, A., Boineau, R., Weinberger, J., Ramanathan, K., Sousa, J.E., Rankin, J., Bhargava, B., Buse, J., Hueb, W., Smith, C.R., Muratov, V., Bansilal, S., King 3rd, S., Bertrand, M., Fuster, V., Investigators, F.T.: Strategies for multivessel revascularization in patients with diabetes. N. Engl. J. Med. 367(25), 2375–2384 (2012). doi: 10.​1056/​NEJMoa1211585 CrossRefPubMed Farkouh, M.E., Domanski, M., Sleeper, L.A., Siami, F.S., Dangas, G., Mack, M., Yang, M., Cohen, D.J., Rosenberg, Y., Solomon, S.D., Desai, A.S., Gersh, B.J., Magnuson, E.A., Lansky, A., Boineau, R., Weinberger, J., Ramanathan, K., Sousa, J.E., Rankin, J., Bhargava, B., Buse, J., Hueb, W., Smith, C.R., Muratov, V., Bansilal, S., King 3rd, S., Bertrand, M., Fuster, V., Investigators, F.T.: Strategies for multivessel revascularization in patients with diabetes. N. Engl. J. Med. 367(25), 2375–2384 (2012). doi: 10.​1056/​NEJMoa1211585 CrossRefPubMed
31.
Zurück zum Zitat Nam, C.W., Mangiacapra, F., Entjes, R., Chung, I.S., Sels, J.W., Tonino, P.A., de Bruyne, B., Pijls, N.H., Fearon, W.F.: Functional SYNTAX score for risk assessment in multivessel coronary artery disease. J. Am. Coll. Cardiol. 58(12), 1211–1218 (2011) CrossRefPubMed Nam, C.W., Mangiacapra, F., Entjes, R., Chung, I.S., Sels, J.W., Tonino, P.A., de Bruyne, B., Pijls, N.H., Fearon, W.F.: Functional SYNTAX score for risk assessment in multivessel coronary artery disease. J. Am. Coll. Cardiol. 58(12), 1211–1218 (2011) CrossRefPubMed
32.
Zurück zum Zitat Pijls, N.H., van Schaardenburgh, P., Manoharan, G., Boersma, E., Bech, J.W., Van’t Veer, M., Bar, F., Hoorntje, J., Koolen, J., Wijns, W., de Bruyne, B.: Percutaneous coronary intervention of functionally nonsignificant stenosis: 5-year follow-up of the DEFER study. J. Am. Coll. Cardiol. 49(21), 2105–2111 (2007) CrossRefPubMed Pijls, N.H., van Schaardenburgh, P., Manoharan, G., Boersma, E., Bech, J.W., Van’t Veer, M., Bar, F., Hoorntje, J., Koolen, J., Wijns, W., de Bruyne, B.: Percutaneous coronary intervention of functionally nonsignificant stenosis: 5-year follow-up of the DEFER study. J. Am. Coll. Cardiol. 49(21), 2105–2111 (2007) CrossRefPubMed
33.
Zurück zum Zitat Nashef, S.A., Roques, F., Michel, P., Gauducheau, E., Lemeshow, S., Salamon, R.: European system for cardiac operative risk evaluation (EuroSCORE) 1. Eur. J. Cardiothorac. Surg. 16(1), 9–13 (1999) CrossRefPubMed Nashef, S.A., Roques, F., Michel, P., Gauducheau, E., Lemeshow, S., Salamon, R.: European system for cardiac operative risk evaluation (EuroSCORE) 1. Eur. J. Cardiothorac. Surg. 16(1), 9–13 (1999) CrossRefPubMed
34.
Zurück zum Zitat Nilsson, J., Algotsson, L., Hoglund, P., Luhrs, C., Brandt, J.: Comparison of 19 pre-operative risk stratification models in open-heart surgery 1. Eur. Heart J. 27(7), 867–874 (2006) CrossRefPubMed Nilsson, J., Algotsson, L., Hoglund, P., Luhrs, C., Brandt, J.: Comparison of 19 pre-operative risk stratification models in open-heart surgery 1. Eur. Heart J. 27(7), 867–874 (2006) CrossRefPubMed
Metadaten
Titel
Guidelines versus reality: is coronary stent application in three-vessel disease standard or the exception?
verfasst von
Roland Linder
J. Zeidler
F. Verheyen
J.-M. Graf von der Schulenburg
A. Haverich
T. Schilling
Publikationsdatum
19.08.2017
Verlag
Springer Berlin Heidelberg
Erschienen in
The European Journal of Health Economics / Ausgabe 6/2018
Print ISSN: 1618-7598
Elektronische ISSN: 1618-7601
DOI
https://doi.org/10.1007/s10198-017-0924-4

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