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01.12.2011 | Case report | Ausgabe 1/2011 Open Access

Journal of Medical Case Reports 1/2011

Half-dose verteporfin photodynamic therapy for bullous variant of central serous chorioretinopathy: a case report

Journal of Medical Case Reports > Ausgabe 1/2011
Winnie WK Ng, Zenith HY Wu, Timothy YY Lai
Wichtige Hinweise

Electronic supplementary material

The online version of this article (doi:10.​1186/​1752-1947-5-208) contains supplementary material, which is available to authorized users.

Competing interests

The authors declare that TYYL has received honorium for lecture fees and serving in the advisory board of Novartis Pharmapeutical Inc. The other authors (WWKN, ZHYW) have no competing interests.

Authors' contributions

WWKN interpreted the patient data and wrote the first draft of the manuscript. ZHYW had a role in writing a final draft of the manuscript and in the preparation of clinical images. TYYL performed the treatment and follow-up on the patient, and was a major contributor to the writing of the manuscript. All authors read and approved the final manuscript.



Central serous chorioretinopathy is characterized by serous neurosensory detachment of the macula and it usually resolves spontaneously with good visual prognosis. In some patients, however, the serous retinal detachment might be very extensive and can result in bullous exudative retinal detachment. We evaluated the use of half-dose verteporfin photodynamic therapy for the treatment of bullous retinal detachment in idiopathic central serous chorioretinopathy.

Case presentation

We report the case of a 51-year-old Chinese man who presented with blurred vision in his right eye and superior visual field defect due to bullous variant of central serous chorioretinopathy. No improvement in vision and retinal detachment was noted after three months of observation and a short course of oral acetazolamide. He was then treated with half-dose verteporfin photodynamic therapy and his visual acuity improved from 20/70 to 20/25 within one month of treatment. Three months after photodynamic therapy, there was complete resolution of sub-retinal fluid and bullous retinal detachment. No recurrence of central serous chorioretinopathy was noted in three years of follow-up.


We report the beneficial effect of photodynamic therapy with half-dose verteporfin as a treatment option for bullous retinal detachment caused by central serous chorioretinopathy.

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