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Cancer Immunology, Immunotherapy

Erschienen in:

01.05.2005 | Opinion Paper

Harnessing host immune responses to preneoplasia: promise and challenges

verfasst von: Madhav V. Dhodapkar

Erschienen in: Cancer Immunology, Immunotherapy | Ausgabe 5/2005

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Abstract

Preneoplastic lesions are more common than clinical cancer and define a population at increased risk for the development of malignancy. Recent studies suggest that the immune system has the capacity to recognize these lesions, and enrichment of preneoplasia-specific immune effectors can be detected in the tumor bed of some preneoplastic lesions such as monoclonal gammopathies. Here, I discuss the promise and challenges of harnessing the immune response against preneoplasia. Approaches to boost the natural host response to these lesions may have a major impact on reducing net cancer burden.

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Titel: Harnessing host immune responses to preneoplasia: promise and challenges
verfasst von: Madhav V. Dhodapkar
Publikationsdatum: 01.05.2005
Verlag: Springer-Verlag
Erschienen in: Cancer Immunology, Immunotherapy / Ausgabe 5/2005
Print ISSN: 0340-7004
Elektronische ISSN: 1432-0851
DOI: https://doi.org/10.1007/s00262-004-0607-8

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