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Erschienen in: Der Urologe 2/2017

02.02.2017 | Szintigrafie | CME

Harnwegsinfekte bei Kindern

verfasst von: E. Lellig, M. Apfelbeck, J. Straub, A. Karl, S. Tritschler, C. G. Stief, M. Riccabona

Erschienen in: Die Urologie | Ausgabe 2/2017

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Zusammenfassung

Harnwegsinfekte (HWI) sind die häufigsten bakteriellen Infektionen im Kindesalter. Diese imponieren jedoch häufig mit unspezifischen Symptomen wie Trinkschwäche, Unterbauchschmerzen oder einer neu aufgetretenen Enuresis nocturna. Die Art der Uringewinnung spielt eine entscheidende Rolle zur Diagnosesicherung. Bei nicht toilettentrainierten Kindern sollte die Uringewinnung mittels Katheterurin oder suprapubischer Punktion erfolgen. Bei toilettentrainierten Kindern ist Mittelstrahlurin zur mikrobiologischen Untersuchung ausreichend. Die rasche Einleitung einer antibiotischen Therapie ist essenziell zur Verhinderung von Parenchymnarben der Nieren. Mittel der Wahl sind hierbei Cephalosporine der 3. Generation. Viele Kinder mit rezidivierenden HWI weisen einen vesikoureteralen Reflux (VUR) auf. Die Vorgehensweise zur Diagnosesicherung eines VUR wird in den einzelnen Ländern unterschiedlich gehandhabt. In Deutschland wird überwiegend die „Bottom-up“-Strategie verfolgt. Diese beinhaltet zunächst die Durchführung eines Miktionszystourethrogramms und im Falle eines Refluxnachweises im Anschluss den Ausschluss oder Nachweis von Parenchymnarben mittels DMSA-Szintigraphie.
Literatur
1.
Zurück zum Zitat Hoberman A et al (1993) Prevalence of urinary tract infection in febrile infants. J Pediatr 123(1):17–23CrossRefPubMed Hoberman A et al (1993) Prevalence of urinary tract infection in febrile infants. J Pediatr 123(1):17–23CrossRefPubMed
2.
Zurück zum Zitat Shaikh N et al (2008) Prevalence of urinary tract infection in childhood: a meta-analysis. Pediatr Infect Dis J 27(4):302–308CrossRefPubMed Shaikh N et al (2008) Prevalence of urinary tract infection in childhood: a meta-analysis. Pediatr Infect Dis J 27(4):302–308CrossRefPubMed
3.
Zurück zum Zitat Hellstrom A et al (1991) Association between urinary symptoms at 7 years old and previous urinary tract infection. Arch Dis Child 66(2):232–234CrossRefPubMedPubMedCentral Hellstrom A et al (1991) Association between urinary symptoms at 7 years old and previous urinary tract infection. Arch Dis Child 66(2):232–234CrossRefPubMedPubMedCentral
4.
Zurück zum Zitat Marild S, Jodal U (1998) Incidence rate of first-time symptomatic urinary tract infection in children under 6 years of age. Acta Paediatr 87(5):549–552CrossRefPubMed Marild S, Jodal U (1998) Incidence rate of first-time symptomatic urinary tract infection in children under 6 years of age. Acta Paediatr 87(5):549–552CrossRefPubMed
5.
Zurück zum Zitat Winberg J et al (1974) Epidemiology of symptomatic urinary tract infection in childhood. Acta Paediatr Scand Suppl 252:1–20CrossRef Winberg J et al (1974) Epidemiology of symptomatic urinary tract infection in childhood. Acta Paediatr Scand Suppl 252:1–20CrossRef
6.
Zurück zum Zitat McCracken GH Jr. (1984) Recurrent urinary tract infections in children. Pediatr Infect Dis 3(3 Suppl):S28–S30CrossRefPubMed McCracken GH Jr. (1984) Recurrent urinary tract infections in children. Pediatr Infect Dis 3(3 Suppl):S28–S30CrossRefPubMed
7.
Zurück zum Zitat Hoberman A et al (2003) Imaging studies after a first febrile urinary tract infection in young children. N Engl J Med 348(3):195–202CrossRefPubMed Hoberman A et al (2003) Imaging studies after a first febrile urinary tract infection in young children. N Engl J Med 348(3):195–202CrossRefPubMed
8.
Zurück zum Zitat Shaikh N et al (2016) Early antibiotic treatment for pediatric febrile urinary tract infection and renal scarring. JAMA Pediatr 170(9):848–854CrossRefPubMed Shaikh N et al (2016) Early antibiotic treatment for pediatric febrile urinary tract infection and renal scarring. JAMA Pediatr 170(9):848–854CrossRefPubMed
9.
Zurück zum Zitat Shaw KN et al (1998) Prevalence of urinary tract infection in febrile young children in the emergency department. Pediatrics 102(2):e16CrossRefPubMed Shaw KN et al (1998) Prevalence of urinary tract infection in febrile young children in the emergency department. Pediatrics 102(2):e16CrossRefPubMed
10.
Zurück zum Zitat Zorc JJ et al (2005) Clinical and demographic factors associated with urinary tract infection in young febrile infants. Pediatrics 116(3):644–648CrossRefPubMed Zorc JJ et al (2005) Clinical and demographic factors associated with urinary tract infection in young febrile infants. Pediatrics 116(3):644–648CrossRefPubMed
11.
Zurück zum Zitat Shaikh N et al (2007) Does this child have a urinary tract infection? JAMA 298(24):2895–2904CrossRefPubMed Shaikh N et al (2007) Does this child have a urinary tract infection? JAMA 298(24):2895–2904CrossRefPubMed
12.
Zurück zum Zitat Pryles CV et al (1959) Comparative bacteriologic study of urine obtained from children by percutaneous suprapubic aspiration of the bladder and by catheter. Pediatrics 24:983–991PubMed Pryles CV et al (1959) Comparative bacteriologic study of urine obtained from children by percutaneous suprapubic aspiration of the bladder and by catheter. Pediatrics 24:983–991PubMed
13.
Zurück zum Zitat Hardy JD, Furnell PM, Brumfitt W (1976) Comparison of sterile bag, clean catch and suprapubic aspiration in the diagnosis of urinary infection in early childhood. Br J Urol 48(4):279–283CrossRefPubMed Hardy JD, Furnell PM, Brumfitt W (1976) Comparison of sterile bag, clean catch and suprapubic aspiration in the diagnosis of urinary infection in early childhood. Br J Urol 48(4):279–283CrossRefPubMed
14.
Zurück zum Zitat Tosif S et al (2012) Contamination rates of different urine collection methods for the diagnosis of urinary tract infections in young children: an observational cohort study. J Paediatr Child Health 48(8):659–664CrossRefPubMed Tosif S et al (2012) Contamination rates of different urine collection methods for the diagnosis of urinary tract infections in young children: an observational cohort study. J Paediatr Child Health 48(8):659–664CrossRefPubMed
15.
Zurück zum Zitat Wingerter S, Bachur R (2011) Risk factors for contamination of catheterized urine specimens in febrile children. Pediatr Emerg Care 27(1):1–4CrossRefPubMed Wingerter S, Bachur R (2011) Risk factors for contamination of catheterized urine specimens in febrile children. Pediatr Emerg Care 27(1):1–4CrossRefPubMed
16.
Zurück zum Zitat Roberts KB (2000) The AAP practice parameter on urinary tract infections in febrile infants and young children. American Academy of Pediatrics. Am Fam Physician 62(8):1815–1822PubMed Roberts KB (2000) The AAP practice parameter on urinary tract infections in febrile infants and young children. American Academy of Pediatrics. Am Fam Physician 62(8):1815–1822PubMed
17.
Zurück zum Zitat Al-Orifi F et al (2000) Urine culture from bag specimens in young children: are the risks too high? J Pediatr 137(2):221–226CrossRefPubMed Al-Orifi F et al (2000) Urine culture from bag specimens in young children: are the risks too high? J Pediatr 137(2):221–226CrossRefPubMed
18.
Zurück zum Zitat Committee on Quality Improvement. Subcommittee on Urinary Tract Infection (1999) Practice parameter: the diagnosis, treatment, and evaluation of the initial urinary tract infection in febrile infants and young children. American Academy of Pediatrics. Pediatrics 103(4 Pt 1):843–852 Committee on Quality Improvement. Subcommittee on Urinary Tract Infection (1999) Practice parameter: the diagnosis, treatment, and evaluation of the initial urinary tract infection in febrile infants and young children. American Academy of Pediatrics. Pediatrics 103(4 Pt 1):843–852
19.
Zurück zum Zitat Weathers WT, Wenzl JE (1969) Suprapubic aspiration of the bladder. Perforation of a viscus other than the bladder. Am J Dis Child 117(5):590–592CrossRefPubMed Weathers WT, Wenzl JE (1969) Suprapubic aspiration of the bladder. Perforation of a viscus other than the bladder. Am J Dis Child 117(5):590–592CrossRefPubMed
20.
Zurück zum Zitat Estrada CR Jr. et al (2009) Nomograms for predicting annual resolution rate of primary vesicoureteral reflux: results from 2,462 children. J Urol 182(4):1535–1541CrossRefPubMed Estrada CR Jr. et al (2009) Nomograms for predicting annual resolution rate of primary vesicoureteral reflux: results from 2,462 children. J Urol 182(4):1535–1541CrossRefPubMed
21.
Zurück zum Zitat Berger C et al (2013) Positioning irrigation of contrast cystography for diagnosis of occult vesicoureteric reflux: association with technetium-99 m dimercaptosuccinic acid scans. J Pediatr Urol 9(6 Pt A):846–850CrossRefPubMed Berger C et al (2013) Positioning irrigation of contrast cystography for diagnosis of occult vesicoureteric reflux: association with technetium-99 m dimercaptosuccinic acid scans. J Pediatr Urol 9(6 Pt A):846–850CrossRefPubMed
22.
Zurück zum Zitat Chang SL, Shortliffe LD (2006) Pediatric urinary tract infections. Pediatr Clin North Am 53(3):379–400CrossRefPubMed Chang SL, Shortliffe LD (2006) Pediatric urinary tract infections. Pediatr Clin North Am 53(3):379–400CrossRefPubMed
23.
Zurück zum Zitat Gaspari RJ et al (2005) Antibiotic resistance trends in paediatric uropathogens. Int J Antimicrob Agents 26(4):267–271CrossRefPubMed Gaspari RJ et al (2005) Antibiotic resistance trends in paediatric uropathogens. Int J Antimicrob Agents 26(4):267–271CrossRefPubMed
24.
Zurück zum Zitat Lutter SA et al (2005) Antibiotic resistance patterns in children hospitalized for urinary tract infections. Arch Pediatr Adolesc Med 159(10):924–928CrossRefPubMed Lutter SA et al (2005) Antibiotic resistance patterns in children hospitalized for urinary tract infections. Arch Pediatr Adolesc Med 159(10):924–928CrossRefPubMed
26.
Zurück zum Zitat Ronald A (2002) The etiology of urinary tract infection: traditional and emerging pathogens. Am J Med 113(Suppl 1 A):14–19CrossRef Ronald A (2002) The etiology of urinary tract infection: traditional and emerging pathogens. Am J Med 113(Suppl 1 A):14–19CrossRef
27.
Zurück zum Zitat Weber LT, Benz MR (2010) Harnwegsinfektionen im Kindesalter. Diagnostik und Therapie. Kinder Jugendmed 10:211–218 Weber LT, Benz MR (2010) Harnwegsinfektionen im Kindesalter. Diagnostik und Therapie. Kinder Jugendmed 10:211–218
28.
Zurück zum Zitat Beetz R, Wagenlehner F (2013) Diagnostics and therapy of urinary tract infections. Urologe A 52(1):21–32CrossRefPubMed Beetz R, Wagenlehner F (2013) Diagnostics and therapy of urinary tract infections. Urologe A 52(1):21–32CrossRefPubMed
29.
Zurück zum Zitat Bryce A et al (2016) Global prevalence of antibiotic resistance in paediatric urinary tract infections caused by Escherichia coli and association with routine use of antibiotics in primary care: systematic review and meta-analysis. BMJ 352:i939CrossRefPubMedPubMedCentral Bryce A et al (2016) Global prevalence of antibiotic resistance in paediatric urinary tract infections caused by Escherichia coli and association with routine use of antibiotics in primary care: systematic review and meta-analysis. BMJ 352:i939CrossRefPubMedPubMedCentral
30.
Zurück zum Zitat Coulthard MG et al (2014) Does prompt treatment of urinary tract infection in preschool children prevent renal scarring: mixed retrospective and prospective audits. Arch Dis Child 99(4):342–347CrossRefPubMed Coulthard MG et al (2014) Does prompt treatment of urinary tract infection in preschool children prevent renal scarring: mixed retrospective and prospective audits. Arch Dis Child 99(4):342–347CrossRefPubMed
31.
Zurück zum Zitat Oh MM et al (2012) The impact of therapeutic delay time on acute scintigraphic lesion and ultimate scar formation in children with first febrile UTI. Eur J Pediatr 171(3):565–570CrossRefPubMed Oh MM et al (2012) The impact of therapeutic delay time on acute scintigraphic lesion and ultimate scar formation in children with first febrile UTI. Eur J Pediatr 171(3):565–570CrossRefPubMed
32.
Zurück zum Zitat Byington CL, Rittichier KK, Bassett KE et al (2003) Serious bacterial infections in febrile infants younger than 90 days of age: the importance of ampicillin-resistant pathogens. Pediatrics 111:964 Byington CL, Rittichier KK, Bassett KE et al (2003) Serious bacterial infections in febrile infants younger than 90 days of age: the importance of ampicillin-resistant pathogens. Pediatrics 111:964
34.
Zurück zum Zitat Jepson RG, Williams G, Craig JC (2012) Cranberries for preventing urinary tract infections. Cochrane Database Syst Rev 10:CD001321PubMed Jepson RG, Williams G, Craig JC (2012) Cranberries for preventing urinary tract infections. Cochrane Database Syst Rev 10:CD001321PubMed
35.
Zurück zum Zitat Salo J et al (2012) Cranberry juice for the prevention of recurrences of urinary tract infections in children: a randomized placebo-controlled trial. Clin Infect Dis 54(3):340–346CrossRefPubMed Salo J et al (2012) Cranberry juice for the prevention of recurrences of urinary tract infections in children: a randomized placebo-controlled trial. Clin Infect Dis 54(3):340–346CrossRefPubMed
36.
Zurück zum Zitat Schwenger EM, Tejani AM, Loewen PS (2015) Probiotics for preventing urinary tract infections in adults and children. Cochrane Database Syst Rev 12:CD008772 Schwenger EM, Tejani AM, Loewen PS (2015) Probiotics for preventing urinary tract infections in adults and children. Cochrane Database Syst Rev 12:CD008772
37.
Zurück zum Zitat Stein R, Beetz R, Thüroff JW (2012) Kinderurologie in Klinik und PraxisCrossRef Stein R, Beetz R, Thüroff JW (2012) Kinderurologie in Klinik und PraxisCrossRef
38.
Zurück zum Zitat Wiswell TE, Geschke DW (1989) Risks from circumcision during the first month of life compared with those for uncircumcised boys. Pediatrics 83(6):1011–1015PubMed Wiswell TE, Geschke DW (1989) Risks from circumcision during the first month of life compared with those for uncircumcised boys. Pediatrics 83(6):1011–1015PubMed
Metadaten
Titel
Harnwegsinfekte bei Kindern
verfasst von
E. Lellig
M. Apfelbeck
J. Straub
A. Karl
S. Tritschler
C. G. Stief
M. Riccabona
Publikationsdatum
02.02.2017
Verlag
Springer Medizin
Erschienen in
Die Urologie / Ausgabe 2/2017
Print ISSN: 2731-7064
Elektronische ISSN: 2731-7072
DOI
https://doi.org/10.1007/s00120-016-0316-x

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