Skip to main content
Erschienen in: Uro-News 7-8/2022

10.07.2022 | Harnwegsinfektionen | Fortbildung

Langzeitschäden mit ungewissen Folgen

Einfluss von Antibiotika auf das Mikrobiom des Urogenitaltrakts

verfasst von: Sarah Yeldan, Dr. med. Tim Schiereck, PD Dr. med. habil. Jennifer Kranz, PD Dr. med. habil. Laila Schneidewind, Dr. med. Lena Biehl, Prof. Dr. med. Igor Tsaur, Prof. Dr. med. Thomas Otto, Dr. med. Dimitri Barski

Erschienen in: Uro-News | Ausgabe 7-8/2022

Einloggen, um Zugang zu erhalten

Auszug

Auch früher steril geglaubte Organsysteme wie der Harntrakt haben eine Standortflora. Antibiotika könnten das Mikrobiom des Menschen also auch hier beeinflussen. Aus möglichen Folgen für die Gesundheit leiten sich Empfehlungen für den korrekten Einsatz von Antibiotika ab. …
Literatur
1.
Zurück zum Zitat Morgan XC et al. Chapter 12: Human microbiome analysis. PLoS Comput Biol 2012;8:e1002808 Morgan XC et al. Chapter 12: Human microbiome analysis. PLoS Comput Biol 2012;8:e1002808
2.
Zurück zum Zitat Schiereck T et al. Urinary bladder microbiome analysis and probiotic treatment options for women ith recurrent urinary tract infections. Urologe A 2022;61:41-51 Schiereck T et al. Urinary bladder microbiome analysis and probiotic treatment options for women ith recurrent urinary tract infections. Urologe A 2022;61:41-51
3.
Zurück zum Zitat Gottschick C et al. The urinary microbiota of men and women and its changes in women during bacterial vaginosis and antibiotic treatment. Microbiome 2017;5:99 Gottschick C et al. The urinary microbiota of men and women and its changes in women during bacterial vaginosis and antibiotic treatment. Microbiome 2017;5:99
4.
Zurück zum Zitat Price TK et al. The Clinical Urine Culture: Enhanced Techniques Improve Detection of Clinically Relevant Microorganisms. J Clin Microbiol 2016;54:1216-22 Price TK et al. The Clinical Urine Culture: Enhanced Techniques Improve Detection of Clinically Relevant Microorganisms. J Clin Microbiol 2016;54:1216-22
5.
Zurück zum Zitat Siddiqui H et al. Alterations of microbiota in urine from women with interstitial cystitis. BMC Microbiology 2012;12:205 Siddiqui H et al. Alterations of microbiota in urine from women with interstitial cystitis. BMC Microbiology 2012;12:205
6.
Zurück zum Zitat Gasiorek M et al. Utility of DNA Next-Generation Sequencing and Expanded Quantitative Urine Culture in Diagnosis and Management of Chronic or Persistent Lower Urinary Tract Symptoms. J Clin Microbiol 2019;58:e00204-19 Gasiorek M et al. Utility of DNA Next-Generation Sequencing and Expanded Quantitative Urine Culture in Diagnosis and Management of Chronic or Persistent Lower Urinary Tract Symptoms. J Clin Microbiol 2019;58:e00204-19
7.
Zurück zum Zitat Hilt EE et al. Urine is not sterile: Use of enhanced urine culture techniques to detect resident bacterial flora in the adult female bladder. J Clin Microbiol 2014;52:871-6 Hilt EE et al. Urine is not sterile: Use of enhanced urine culture techniques to detect resident bacterial flora in the adult female bladder. J Clin Microbiol 2014;52:871-6
8.
Zurück zum Zitat Pearce MM et al. The Female Urinary Microbiome: a Comparison of Women with and without Urgency Urinary Incontinence. mBio 2014;5:e01283-14 Pearce MM et al. The Female Urinary Microbiome: a Comparison of Women with and without Urgency Urinary Incontinence. mBio 2014;5:e01283-14
9.
Zurück zum Zitat Meštrović T et al. The Role of Gut, Vaginal, and Urinary Microbiome in Urinary Tract Infections: From Bench to Bedside. Diagnostics 2021;11:7 Meštrović T et al. The Role of Gut, Vaginal, and Urinary Microbiome in Urinary Tract Infections: From Bench to Bedside. Diagnostics 2021;11:7
10.
Zurück zum Zitat Amabebe E et al. Female Gut and Genital Tract Microbiota-Induced Crosstalk and Differential Effects of Short-Chain Fatty Acids on Immune Sequelae. Front Immunol 2020;11:2184 Amabebe E et al. Female Gut and Genital Tract Microbiota-Induced Crosstalk and Differential Effects of Short-Chain Fatty Acids on Immune Sequelae. Front Immunol 2020;11:2184
11.
Zurück zum Zitat Aira A et al. rUTI Resolution After FMT for Clostridioides difficile Infection: A Case Report. Infect Dis Ther 2021;10:1065-71 Aira A et al. rUTI Resolution After FMT for Clostridioides difficile Infection: A Case Report. Infect Dis Ther 2021;10:1065-71
12.
Zurück zum Zitat Tariq R et al. Fecal Microbiota Transplantation for Recurrent Clostridium difficile Infection Reduces Recurrent Urinary Tract Infection Frequency. Clin Infect Dis 2017;65:1745-7 Tariq R et al. Fecal Microbiota Transplantation for Recurrent Clostridium difficile Infection Reduces Recurrent Urinary Tract Infection Frequency. Clin Infect Dis 2017;65:1745-7
13.
Zurück zum Zitat Biehl LM et al. Fecal microbiota transplantation in a kidney transplant recipient with recurrent urinary tract infection. Infection 2018;46:871-4 Biehl LM et al. Fecal microbiota transplantation in a kidney transplant recipient with recurrent urinary tract infection. Infection 2018;46:871-4
14.
Zurück zum Zitat Ghani R et al. Disease Prevention Not Decolonization: A Model for Fecal Microbiota Transplantation in Patients Colonized With Multidrug-resistant Organisms. Clin Infect Dis 2021;72: 1444-7 Ghani R et al. Disease Prevention Not Decolonization: A Model for Fecal Microbiota Transplantation in Patients Colonized With Multidrug-resistant Organisms. Clin Infect Dis 2021;72: 1444-7
15.
Zurück zum Zitat Mulder M et al. The effect of antimicrobial drug use on the composition of the genitourinary microbiota in an elderly population. BMC Microbiol 2019;19:9 Mulder M et al. The effect of antimicrobial drug use on the composition of the genitourinary microbiota in an elderly population. BMC Microbiol 2019;19:9
16.
Zurück zum Zitat Vaughan MH et al. The Urinary Microbiome in Postmenopausal Women with Recurrent Urinary Tract Infections. J Urol 2021;206:1222-31 Vaughan MH et al. The Urinary Microbiome in Postmenopausal Women with Recurrent Urinary Tract Infections. J Urol 2021;206:1222-31
17.
Zurück zum Zitat Neugent ML et al. Recurrent urinary tract infection and estrogen shape the taxonomic ecology and functional potential of the postmenopausal urobiome. bioRxiv 2021; https://doi.org/hw3h Neugent ML et al. Recurrent urinary tract infection and estrogen shape the taxonomic ecology and functional potential of the postmenopausal urobiome. bioRxiv 2021; https://​doi.​org/​hw3h
18.
Zurück zum Zitat Jernberg C et al. Long-term impacts of antibiotic exposure on the human intestinal microbiota. Microbiology (Reading) 2010;156:3216-23 Jernberg C et al. Long-term impacts of antibiotic exposure on the human intestinal microbiota. Microbiology (Reading) 2010;156:3216-23
19.
Zurück zum Zitat Jernberg C et al. Long-term ecological impacts of antibiotic administration on the human intestinal microbiota. Isme J 2007;1:56-66 Jernberg C et al. Long-term ecological impacts of antibiotic administration on the human intestinal microbiota. Isme J 2007;1:56-66
20.
Zurück zum Zitat Cai T et al. Asymptomatic bacteriuria treatment is associated with a higher prevalence of antibiotic resistant strains in women with urinary tract infections. Clin Infect Dis 2015;61:1655-61 Cai T et al. Asymptomatic bacteriuria treatment is associated with a higher prevalence of antibiotic resistant strains in women with urinary tract infections. Clin Infect Dis 2015;61:1655-61
21.
Zurück zum Zitat Stewardson AJ et al. Effect of outpatient antibiotics for urinary tract infections on antimicrobial resistance among commensal Enterobacteriaceae: a multinational prospective cohort study. Clin Microbiol Infect 2018;24:972-9 Stewardson AJ et al. Effect of outpatient antibiotics for urinary tract infections on antimicrobial resistance among commensal Enterobacteriaceae: a multinational prospective cohort study. Clin Microbiol Infect 2018;24:972-9
22.
Zurück zum Zitat Wang J et al. Network of microbial and antibiotic interactions drive colonization and infection with multidrug-resistant organisms. Proc Natl Acad Sci USA 2017;114:10467-72 Wang J et al. Network of microbial and antibiotic interactions drive colonization and infection with multidrug-resistant organisms. Proc Natl Acad Sci USA 2017;114:10467-72
23.
Zurück zum Zitat Biehl LM et al. Longitudinal variability in the urinary microbiota of healthy premenopausal women and the relation to neighboring microbial communities: A pilot study. PLoS One 2022;17:e0262095 Biehl LM et al. Longitudinal variability in the urinary microbiota of healthy premenopausal women and the relation to neighboring microbial communities: A pilot study. PLoS One 2022;17:e0262095
Metadaten
Titel
Langzeitschäden mit ungewissen Folgen
Einfluss von Antibiotika auf das Mikrobiom des Urogenitaltrakts
verfasst von
Sarah Yeldan
Dr. med. Tim Schiereck
PD Dr. med. habil. Jennifer Kranz
PD Dr. med. habil. Laila Schneidewind
Dr. med. Lena Biehl
Prof. Dr. med. Igor Tsaur
Prof. Dr. med. Thomas Otto
Dr. med. Dimitri Barski
Publikationsdatum
10.07.2022
Verlag
Springer Medizin
Erschienen in
Uro-News / Ausgabe 7-8/2022
Print ISSN: 1432-9026
Elektronische ISSN: 2196-5676
DOI
https://doi.org/10.1007/s00092-022-4933-y

Weitere Artikel der Ausgabe 7-8/2022

Uro-News 7-8/2022 Zur Ausgabe

Industrieforum

Industrieforum

Update Urologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.