High intake of dietary fibres has been associated with a reduced risk of DD. However, reports on which type of dietary fibre intake that is most beneficial have been conflicting. The aim of this study was to investigate the association between different dietary fibres and hospitalisation due to diverticular disease (DD) of the colon.
This was a major cohort study. The Swedish Mammography Cohort and the Cohort of Swedish Men were linked to the Swedish Inpatient Register and the Causes of Death Register. Data on the intake of dietary fibre were collected through questionnaires. The effect of intake (in quartiles) of different types of dietary fibre on the incidence of hospitalisation due to DD was investigated using multivariable Cox regression. Estimates were adjusted according to age, BMI, physical activity, co-morbidity, intake of corticosteroids, smoking, alcohol intake and education level.
Women with intake of fruit and vegetable fibres in the highest quartile (median 12.6 g/day) had a 30% decreased risk of hospitalisation compared to those with the lowest intake (4.1 g/day). Men within the highest quartile (10.3 g/day) had a 32% decreased risk compared to those with a low intake (2.9 g/day). High intake of fibres from cereals did not affect the risk.
A high intake of fruits and vegetables may reduce the risk of hospitalisation due to DD. Intake of cereals did not influence the risk.
Etzioni DA, Cannom RR, Ault GT, Beart RW Jr, Kaiser AM (2009) Diverticulitis in California from 1995 to 2006: increased rates of treatment for younger patients. Am Surg 75(10):981–985
Granlund J, Svensson T, Olen O, Hjern F, Pedersen NL, Magnusson PK, Schmidt PT (2012) The genetic influence on diverticular disease—a twin study. Alimentary Pharmacol Ther 35(9):1103–1107. https://doi.org/10.1111/j.1365-2036.2012.05069.x
Strate LL, Erichsen R, Baron JA, Mortensen J, Pedersen JK, Riis AH, Christensen K, Sorensen HT (2013) Heritability and familial aggregation of diverticular disease: a population-based study of twins and siblings. Gastroenterology 144(4):736–742.e731. https://doi.org/10.1053/j.gastro.2012.12.030(quiz e714)CrossRef
Aldoori W, Ryan-Harshman M (2002) Preventing diverticular disease. Review of recent evidence on high-fibre diets. Can Family Phys Med de Family Can 48:1632–1637
Aldoori WH, Giovannucci EL, Rockett HR, Sampson L, Rimm EB, Willett WC (1998) A prospective study of dietary fiber types and symptomatic diverticular disease in men. J Nutr 128(4):714–719 CrossRef
Painter NS, Burkitt DP (1971) Diverticular disease of the colon: a deficiency disease of Western civilization. Br Med J 2(5759):450–454 CrossRef
Peery AF, Barrett PR, Park D, Rogers AJ, Galanko JA, Martin CF, Sandler RS (2012) A high-fiber diet does not protect against asymptomatic diverticulosis. Gastroenterology 142(2):266–272.e261. https://doi.org/10.1053/j.gastro.2011.10.035CrossRef
Strate LL, Keeley BR, Cao Y, Wu K, Giovannucci EL, Chan AT (2017) Western dietary pattern increases, and prudent dietary pattern decreases, risk of incident diverticulitis in a prospective cohort study. Gastroenterology 152(5):1023–1030.e1022. https://doi.org/10.1053/j.gastro.2016.12.038CrossRef
Cao Y, Strate LL, Keeley BR, Tam I, Wu K, Giovannucci EL, Chan AT (2017) Meat intake and risk of diverticulitis among men. Gut. https://doi.org/10.1136/gutjnl-2016-313082
Lampe JW, Slavin JL, Melcher EA, Potter JD (1992) Effects of cereal and vegetable fiber feeding on potential risk factors for colon cancer. Cancer Epidemiol Biomarker Prev 1(3):207–211
Aldoori WH, Giovannucci EL, Rimm EB, Wing AL, Trichopoulos DV, Willett WC (1994) A prospective study of diet and the risk of symptomatic diverticular disease in men. Am J Clin Nutr 60(5):757–764 CrossRef
Messerer M, Johansson SE, Wolk A (2004) The validity of questionnaire-based micronutrient intake estimates is increased by including dietary supplement use in Swedish men. J Nutr 134(7):1800–1805 CrossRef
Wolk A, Ljung H, Vessby B, Hunter D, Willett WC (1998) Effect of additional questions about fat on the validity of fat estimates from a food frequency questionnaire. Study Group of MRS SWEA. Eur J Clin Nutr 52(3):186–192 CrossRef
Cox D (1972) Regression models and life tables (with discussion). J R Stat Soc B 32:187–220
von Elm E, Altman DG, Egger M, Pocock SJ, Gotzsche PC, Vandenbroucke JP (2007) The strengthening the reporting of observational studies in epidemiology (STROBE) statement: guidelines for reporting observational studies. Lancet 370(9596):1453–1457. https://doi.org/10.1016/s0140-6736(07)61602-xCrossRef
Aldoori WH (1997) The protective role of dietary fiber in diverticular disease. Adv Exp Med Biol 427:291–308 CrossRef
Miettinen TA, Tarpila S (1978) Fecal beta-sitosterol in patients with diverticular disease of the colon and in vegetarians. Scand J Gastroenterol 13(5):573–576 CrossRef
Brodribb AJ (1977) Treatment of symptomatic diverticular disease with a high-fibre diet. Lancet 1(8013):664–666 CrossRef
- High intake of dietary fibre from fruit and vegetables reduces the risk of hospitalisation for diverticular disease
Mahmood W. Mahmood
- Springer Berlin Heidelberg
- European Journal of Nutrition
Print ISSN: 1436-6207
Elektronische ISSN: 1436-6215