Skip to main content
Erschienen in: Clinical Orthopaedics and Related Research® 2/2014

01.02.2014 | Symposium: 2013 Hip Society Proceedings

High Rate of Infection After Aseptic Revision of Failed Metal-on-Metal Total Hip Arthroplasty

verfasst von: Cody C. Wyles, BS, Robert E. Van Demark III, MD, Rafael J. Sierra, MD, Robert T. Trousdale, MD

Erschienen in: Clinical Orthopaedics and Related Research® | Ausgabe 2/2014

Einloggen, um Zugang zu erhalten

Abstract

Background

Evidence suggests some metal-on-metal (MOM) THAs have higher rates of failure and subsequent revision than other bearing surfaces. However, there are few studies demonstrating how these patients fare after revision.

Questions/purposes

We asked: (1) What is the short-term survivorship of revision THA in patients whose index THAs employed MOM bearings? (2) What are the causes of failure of revision THA in these patients (ie, what are the indications for repeat revision)? (3) What are the most common complications after revisions of MOM THAs?

Methods

We identified 37 patients (24 women, 13 men; mean age, 55 years; 37 hips) revised for aseptic failure of primary stemmed MOM THAs. Reasons for revision included pain with loose components (n = 19), adverse reaction to metal debris (n = 8), periprosthetic fracture (n = 4), impingement (n = 3), dislocation (n = 2), and pain of unknown origin (n = 1). Minimum followup was 24 months (mean, 33 months; range, 24–81 months) postrevision, but 11 were not seen in the last 2 years as our routine followup is at 2 and 5 years. Clinical histories were reviewed for reasons for failure of the MOM THAs and complications associated with revision surgery.

Results

Survivorship free from further revision for any cause was 95% at 24 months and 92% at latest followup (24–81 months). There were three repeat revisions, all for periprosthetic infection, and all were treated with two-stage reimplantation. No other complications were observed.

Conclusions

We observed a higher-than-expected rate of infection after revision of MOM THAs. The infection rate was higher in this report than in an earlier series looking at revision THAs for other indications at our institution. As revision of MOM THA becomes more common, it will be important to continue monitoring postrevision outcomes and providing treatment strategies to mitigate complications for these patients.

Level of Evidence

Level IV, therapeutic study. See Instructions for Authors for a complete description of levels of evidence.
Literatur
1.
Zurück zum Zitat Barrett WP, Kindsfater KA, Lesko JP. Large-diameter modular metal-on-metal total hip arthroplasty: incidence of revision for adverse reaction to metallic debris. J Arthroplasty. 2012;27:976–983.e1.PubMed Barrett WP, Kindsfater KA, Lesko JP. Large-diameter modular metal-on-metal total hip arthroplasty: incidence of revision for adverse reaction to metallic debris. J Arthroplasty. 2012;27:976–983.e1.PubMed
2.
Zurück zum Zitat Cohen D. Revision rates for metal on metal hip joints are double that of other materials. BMJ. 2011;343:d5977.PubMedCrossRef Cohen D. Revision rates for metal on metal hip joints are double that of other materials. BMJ. 2011;343:d5977.PubMedCrossRef
3.
Zurück zum Zitat Evans EM, Freeman MA, Miller AJ, Vernon-Roberts B. Metal sensitivity as a cause of bone necrosis and loosening of the prosthesis in total joint replacement. J Bone Joint Surg Br. 1974;56:626–642.PubMed Evans EM, Freeman MA, Miller AJ, Vernon-Roberts B. Metal sensitivity as a cause of bone necrosis and loosening of the prosthesis in total joint replacement. J Bone Joint Surg Br. 1974;56:626–642.PubMed
4.
Zurück zum Zitat Grammatopolous G, Pandit H, Kwon YM, Gundle R, McLardy-Smith P, Beard DJ, Murray DW, Gill HS. Hip resurfacings revised for inflammatory pseudotumour have a poor outcome. J Bone Joint Surg Br. 2009;91:1019–1024.PubMedCrossRef Grammatopolous G, Pandit H, Kwon YM, Gundle R, McLardy-Smith P, Beard DJ, Murray DW, Gill HS. Hip resurfacings revised for inflammatory pseudotumour have a poor outcome. J Bone Joint Surg Br. 2009;91:1019–1024.PubMedCrossRef
5.
Zurück zum Zitat Gruber FW, Bock A, Trattnig S, Lintner F, Ritschl P. Cystic lesion of the groin due to metallosis: a rare long-term complication of metal-on-metal total hip arthroplasty. J Arthroplasty. 2007;22:923–927.PubMedCrossRef Gruber FW, Bock A, Trattnig S, Lintner F, Ritschl P. Cystic lesion of the groin due to metallosis: a rare long-term complication of metal-on-metal total hip arthroplasty. J Arthroplasty. 2007;22:923–927.PubMedCrossRef
6.
Zurück zum Zitat Hanssen AD, Rand JA. Evaluation and treatment of infection at the site of a total hip or knee arthroplasty. Instr Course Lect. 1999;48:111–122.PubMed Hanssen AD, Rand JA. Evaluation and treatment of infection at the site of a total hip or knee arthroplasty. Instr Course Lect. 1999;48:111–122.PubMed
7.
Zurück zum Zitat Huber M, Reinisch G, Trettenhahn G, Zweymuller K, Lintner F. Presence of corrosion products and hypersensitivity-associated reactions in periprosthetic tissue after aseptic loosening of total hip replacements with metal bearing surfaces. Acta Biomater. 2009;5:172–180.PubMedCrossRef Huber M, Reinisch G, Trettenhahn G, Zweymuller K, Lintner F. Presence of corrosion products and hypersensitivity-associated reactions in periprosthetic tissue after aseptic loosening of total hip replacements with metal bearing surfaces. Acta Biomater. 2009;5:172–180.PubMedCrossRef
8.
Zurück zum Zitat Huo MH, Stockton KG, Mont MA, Bucholz RW. What’s new in total hip arthroplasty? J Bone Joint Surg Am. 2012;94:1721–1727.PubMedCrossRef Huo MH, Stockton KG, Mont MA, Bucholz RW. What’s new in total hip arthroplasty? J Bone Joint Surg Am. 2012;94:1721–1727.PubMedCrossRef
9.
Zurück zum Zitat Jameson SS, Baker PN, Mason J, Porter ML, Deehan DJ, Reed MR. Independent predictors of revision following metal-on-metal hip resurfacing: a retrospective cohort study using National Joint Registry data. J Bone Joint Surg Br. 2012;94:746–754.PubMedCrossRef Jameson SS, Baker PN, Mason J, Porter ML, Deehan DJ, Reed MR. Independent predictors of revision following metal-on-metal hip resurfacing: a retrospective cohort study using National Joint Registry data. J Bone Joint Surg Br. 2012;94:746–754.PubMedCrossRef
10.
Zurück zum Zitat Judd KT, Noiseux N. Concomitant infection and local metal reaction in patients undergoing revision of metal on metal total hip arthroplasty. Iowa Orthop J. 2011;31:59–63.PubMedCentralPubMed Judd KT, Noiseux N. Concomitant infection and local metal reaction in patients undergoing revision of metal on metal total hip arthroplasty. Iowa Orthop J. 2011;31:59–63.PubMedCentralPubMed
11.
Zurück zum Zitat Korovessis P, Petsinis G, Repanti M, Repantis T. Metallosis after contemporary metal-on-metal total hip arthroplasty: five to nine-year follow-up. J Bone Joint Surg Am. 2006;88:1183–1191.PubMedCrossRef Korovessis P, Petsinis G, Repanti M, Repantis T. Metallosis after contemporary metal-on-metal total hip arthroplasty: five to nine-year follow-up. J Bone Joint Surg Am. 2006;88:1183–1191.PubMedCrossRef
12.
Zurück zum Zitat Kwon YM, Thomas P, Summer B, Pandit H, Taylor A, Beard D, Murray DW, Gill HS. Lymphocyte proliferation responses in patients with pseudotumors following metal-on-metal hip resurfacing arthroplasty. J Orthop Res. 2010;28:444–450.PubMed Kwon YM, Thomas P, Summer B, Pandit H, Taylor A, Beard D, Murray DW, Gill HS. Lymphocyte proliferation responses in patients with pseudotumors following metal-on-metal hip resurfacing arthroplasty. J Orthop Res. 2010;28:444–450.PubMed
13.
Zurück zum Zitat Maezawa K, Nozawa M, Matsuda K, Sugimoto M, Shitoto K, Kurosawa H. Serum chromium levels before and after revision surgery for loosened metal-on-metal total hip arthroplasty. J Arthroplasty. 2009;24:549–553.PubMedCrossRef Maezawa K, Nozawa M, Matsuda K, Sugimoto M, Shitoto K, Kurosawa H. Serum chromium levels before and after revision surgery for loosened metal-on-metal total hip arthroplasty. J Arthroplasty. 2009;24:549–553.PubMedCrossRef
14.
Zurück zum Zitat Mikhael MM, Hanssen AD, Sierra RJ. Failure of metal-on-metal total hip arthroplasty mimicking hip infection: a report of two cases. J Bone Joint Surg Am. 2009;91:443–446.PubMedCrossRef Mikhael MM, Hanssen AD, Sierra RJ. Failure of metal-on-metal total hip arthroplasty mimicking hip infection: a report of two cases. J Bone Joint Surg Am. 2009;91:443–446.PubMedCrossRef
15.
Zurück zum Zitat Milosev I, Kovac S, Trebse R, Levasic V, Pisot V. Comparison of ten-year survivorship of hip prostheses with use of conventional polyethylene, metal-on-metal, or ceramic-on-ceramic bearings. J Bone Joint Surg Am. 2012;94:1756–1763.PubMedCrossRef Milosev I, Kovac S, Trebse R, Levasic V, Pisot V. Comparison of ten-year survivorship of hip prostheses with use of conventional polyethylene, metal-on-metal, or ceramic-on-ceramic bearings. J Bone Joint Surg Am. 2012;94:1756–1763.PubMedCrossRef
16.
Zurück zum Zitat Milosev I, Trebse R, Kovac S, Cor A, Pisot V. Survivorship and retrieval analysis of Sikomet metal-on-metal total hip replacements at a mean of seven years. J Bone Joint Surg Am. 2006;88:1173–1182.PubMedCrossRef Milosev I, Trebse R, Kovac S, Cor A, Pisot V. Survivorship and retrieval analysis of Sikomet metal-on-metal total hip replacements at a mean of seven years. J Bone Joint Surg Am. 2006;88:1173–1182.PubMedCrossRef
17.
Zurück zum Zitat Molli RG, Lombardi AV Jr, Berend KR, Adams JB, Sneller MA. Metal-on-metal vs metal-on-improved polyethylene bearings in total hip arthroplasty. J Arthroplasty. 2011;26:8–13.PubMedCrossRef Molli RG, Lombardi AV Jr, Berend KR, Adams JB, Sneller MA. Metal-on-metal vs metal-on-improved polyethylene bearings in total hip arthroplasty. J Arthroplasty. 2011;26:8–13.PubMedCrossRef
18.
Zurück zum Zitat Munro JT, Masri BA, Duncan CP, Garbuz DS. High Complication Rate After Revision of Large-head Metal-on-metal Total Hip Arthroplasty. Clin Orthop Relat Res. 2013 April 10 [Epub ahead of print]. Munro JT, Masri BA, Duncan CP, Garbuz DS. High Complication Rate After Revision of Large-head Metal-on-metal Total Hip Arthroplasty. Clin Orthop Relat Res. 2013 April 10 [Epub ahead of print].
19.
Zurück zum Zitat Pandit H, Glyn-Jones S, McLardy-Smith P, Gundle R, Whitwell D, Gibbons CL, Ostlere S, Athanasou N, Gill HS, Murray DW. Pseudotumours associated with metal-on-metal hip resurfacings. J Bone Joint Surg Br. 2008;90:847–851.PubMedCrossRef Pandit H, Glyn-Jones S, McLardy-Smith P, Gundle R, Whitwell D, Gibbons CL, Ostlere S, Athanasou N, Gill HS, Murray DW. Pseudotumours associated with metal-on-metal hip resurfacings. J Bone Joint Surg Br. 2008;90:847–851.PubMedCrossRef
20.
Zurück zum Zitat Pandit H, Vlychou M, Whitwell D, Crook D, Luqmani R, Ostlere S, Murray DW, Athanasou NA. Necrotic granulomatous pseudotumours in bilateral resurfacing hip arthroplasties: evidence for a type IV immune response. Virchows Arch. 2008;453:529–534.PubMedCrossRef Pandit H, Vlychou M, Whitwell D, Crook D, Luqmani R, Ostlere S, Murray DW, Athanasou NA. Necrotic granulomatous pseudotumours in bilateral resurfacing hip arthroplasties: evidence for a type IV immune response. Virchows Arch. 2008;453:529–534.PubMedCrossRef
21.
Zurück zum Zitat Park YS, Moon YW, Lim SJ, Yang JM, Ahn G, Choi YL. Early osteolysis following second-generation metal-on-metal hip replacement. J Bone Joint Surg Am. 2005;87:1515–1521.PubMedCrossRef Park YS, Moon YW, Lim SJ, Yang JM, Ahn G, Choi YL. Early osteolysis following second-generation metal-on-metal hip replacement. J Bone Joint Surg Am. 2005;87:1515–1521.PubMedCrossRef
22.
Zurück zum Zitat Petrie RS, Hanssen AD, Osmon DR, Ilstrup D. Metal-backed patellar component failure in total knee arthroplasty: a possible risk for late infection. Am J Orthop (Belle Mead NJ). 1998;27:172–176.PubMed Petrie RS, Hanssen AD, Osmon DR, Ilstrup D. Metal-backed patellar component failure in total knee arthroplasty: a possible risk for late infection. Am J Orthop (Belle Mead NJ). 1998;27:172–176.PubMed
23.
Zurück zum Zitat Quesada MJ, Marker DR, Mont MA. Metal-on-metal hip resurfacing: advantages and disadvantages. J Arthroplasty. 2008;23:69–73.PubMedCrossRef Quesada MJ, Marker DR, Mont MA. Metal-on-metal hip resurfacing: advantages and disadvantages. J Arthroplasty. 2008;23:69–73.PubMedCrossRef
24.
Zurück zum Zitat Rajpura A, Porter ML, Gambhir AK, Freemont AJ, Board TN. Clinical experience of revision of metal on metal hip arthroplasty for aseptic lymphocyte dominated vasculitis associated lesions (ALVAL). Hip Int. 2011;21:43–51.PubMedCrossRef Rajpura A, Porter ML, Gambhir AK, Freemont AJ, Board TN. Clinical experience of revision of metal on metal hip arthroplasty for aseptic lymphocyte dominated vasculitis associated lesions (ALVAL). Hip Int. 2011;21:43–51.PubMedCrossRef
25.
Zurück zum Zitat Sehatzadeh S, Kaulback K, Levin L. Metal-on-metal hip resurfacing arthroplasty: an analysis of safety and revision rates. Ont Health Technol Assess Ser. 2012;12:1–63. Sehatzadeh S, Kaulback K, Levin L. Metal-on-metal hip resurfacing arthroplasty: an analysis of safety and revision rates. Ont Health Technol Assess Ser. 2012;12:1–63.
26.
Zurück zum Zitat Willert HG, Buchhorn GH, Fayyazi A, Flury R, Windler M, Koster G, Lohmann CH. Metal-on-metal bearings and hypersensitivity in patients with artificial hip joints: a clinical and histomorphological study. J Bone Joint Surg Am. 2005;87:28–36.PubMedCrossRef Willert HG, Buchhorn GH, Fayyazi A, Flury R, Windler M, Koster G, Lohmann CH. Metal-on-metal bearings and hypersensitivity in patients with artificial hip joints: a clinical and histomorphological study. J Bone Joint Surg Am. 2005;87:28–36.PubMedCrossRef
27.
Zurück zum Zitat Zijlstra WP, Cheung J, Sietsma MS, van Raay JJ, Deutman R. No superiority of cemented metal-on-metal vs metal-on-polyethylene THA at 5-year follow-up. Orthopedics. 2009;32:479.PubMedCrossRef Zijlstra WP, Cheung J, Sietsma MS, van Raay JJ, Deutman R. No superiority of cemented metal-on-metal vs metal-on-polyethylene THA at 5-year follow-up. Orthopedics. 2009;32:479.PubMedCrossRef
Metadaten
Titel
High Rate of Infection After Aseptic Revision of Failed Metal-on-Metal Total Hip Arthroplasty
verfasst von
Cody C. Wyles, BS
Robert E. Van Demark III, MD
Rafael J. Sierra, MD
Robert T. Trousdale, MD
Publikationsdatum
01.02.2014
Verlag
Springer US
Erschienen in
Clinical Orthopaedics and Related Research® / Ausgabe 2/2014
Print ISSN: 0009-921X
Elektronische ISSN: 1528-1132
DOI
https://doi.org/10.1007/s11999-013-3157-6

Weitere Artikel der Ausgabe 2/2014

Clinical Orthopaedics and Related Research® 2/2014 Zur Ausgabe

Symposium: 2013 Hip Society Proceedings

Editorial Comment: Symposium: 2013 Hip Society Proceedings

Arthropedia

Grundlagenwissen der Arthroskopie und Gelenkchirurgie. Erweitert durch Fallbeispiele, Videos und Abbildungen. 
» Jetzt entdecken

Update Orthopädie und Unfallchirurgie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.