The online version of this article (doi:10.1007/s00330-016-4419-y) contains supplementary material, which is available to authorized users.
We studied the feasibility of high-resolution T2-weighted cervical cancer imaging on an ultra-high-field 7.0-T magnetic resonance imaging (MRI) system using an endorectal antenna of 4.7-mm thickness.
A feasibility study on 20 stage IB1–IIB cervical cancer patients was conducted. All underwent pre-treatment 1.5-T MRI. At 7.0-T MRI, an external transmit/receive array with seven dipole antennae and a single endorectal monopole receive antenna were used. Discomfort levels were assessed. Following individualised phase-based B1+ shimming, T2-weighted turbo spin echo sequences were completed.
Patients had stage IB1 (n = 9), IB2 (n = 4), IIA1 (n = 1) or IIB (n = 6) cervical cancer. Discomfort (ten-point scale) was minimal at placement and removal of the endorectal antenna with a median score of 1 (range, 0–5) and 0 (range, 0–2) respectively. Its use did not result in adverse events or pre-term session discontinuation. To demonstrate feasibility, T2-weighted acquisitions from 7.0-T MRI are presented in comparison to 1.5-T MRI. Artefacts on 7.0-T MRI were due to motion, locally destructive B1 interference, excessive B1 under the external antennae and SENSE reconstruction.
High-resolution T2-weighted 7.0-T MRI of stage IB1–IIB cervical cancer is feasible. The addition of an endorectal antenna is well tolerated by patients.
• High resolution T2-weighted 7.0-T MRI of the inner female pelvis is challenging
• We demonstrate a feasible approach for T2-weighted 7.0-T MRI of cervical cancer
• An endorectal monopole receive antenna is well tolerated by participants
• The endorectal antenna did not lead to adverse events or session discontinuation
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- High-resolution T2-weighted cervical cancer imaging: a feasibility study on ultra-high-field 7.0-T MRI with an endorectal monopole antenna
Jacob P. Hoogendam
Irene M. L. Kalleveen
Catalina S. Arteaga de Castro
Alexander J. E. Raaijmakers
René H. M. Verheijen
Maurice A. A. J. van den Bosch
Dennis W. J. Klomp
Ronald P. Zweemer
Wouter B. Veldhuis
- Springer Berlin Heidelberg
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