The online version of this article (doi:10.1007/s00330-016-4419-y) contains supplementary material, which is available to authorized users.
We studied the feasibility of high-resolution T2-weighted cervical cancer imaging on an ultra-high-field 7.0-T magnetic resonance imaging (MRI) system using an endorectal antenna of 4.7-mm thickness.
A feasibility study on 20 stage IB1–IIB cervical cancer patients was conducted. All underwent pre-treatment 1.5-T MRI. At 7.0-T MRI, an external transmit/receive array with seven dipole antennae and a single endorectal monopole receive antenna were used. Discomfort levels were assessed. Following individualised phase-based B1 + shimming, T2-weighted turbo spin echo sequences were completed.
Patients had stage IB1 (n = 9), IB2 (n = 4), IIA1 (n = 1) or IIB (n = 6) cervical cancer. Discomfort (ten-point scale) was minimal at placement and removal of the endorectal antenna with a median score of 1 (range, 0–5) and 0 (range, 0–2) respectively. Its use did not result in adverse events or pre-term session discontinuation. To demonstrate feasibility, T2-weighted acquisitions from 7.0-T MRI are presented in comparison to 1.5-T MRI. Artefacts on 7.0-T MRI were due to motion, locally destructive B1 interference, excessive B1 under the external antennae and SENSE reconstruction.
High-resolution T2-weighted 7.0-T MRI of stage IB1–IIB cervical cancer is feasible. The addition of an endorectal antenna is well tolerated by patients.
• High resolution T 2 -weighted 7.0-T MRI of the inner female pelvis is challenging
• We demonstrate a feasible approach for T 2 -weighted 7.0-T MRI of cervical cancer
• An endorectal monopole receive antenna is well tolerated by participants
• The endorectal antenna did not lead to adverse events or session discontinuation
FIGO Committee on Gynecologic Oncology (2014) FIGO staging for carcinoma of the vulva, cervix, and corpus uteri. Int J Gynaecol Obstet 125:97–98 CrossRef
Quinn M, Benedet J, Odicino F et al (2006) Carcinoma of the cervix uteri. FIGO 26th Annual Report on the Results of Treatment in Gynecological Cancer. Int J Gynecol Obstet 95(Suppl 1):S43–S103 CrossRef
Qin Y, Peng Z, Lou J et al (2009) Discrepancies between clinical staging and pathological findings of operable cervical carcinoma with stage IB-IIB: a retrospective analysis of 818 patients. Aust NZJ Obstet Gynaecol 49:542–544 CrossRef
Guideline cervical cancer, version 3.0, subsection; diagnostics. Available at www.oncoline.nl, a website from the Integraal kankercentrum Nederland (IKNL). Accessed 15 January 2014
NCCN Clinical practice guideline in oncology. Cervical cancer. Version 3.2013. Available at www.nccn.org. Accessed 20 January 2014
Ertürk MA, El-Sharkawy AM, Bottomley PA (2008) Interventional loopless antenna at 7 T. Magn Reson Med 68:980–988 CrossRef
National Cancer Institute, US department of health and human services. Common Terminology Criteria for Adverse Events (CTCAE), version 4.03. Available at http://evs.nci.nih.gov. Accessed 31 May 2013
International Commission on Non-Ionizing Radiation Protection (2004) Medical magnetic resonance (MR) procedures: protection of patients. Health Phys 87:197–216 CrossRef
Kalleveen IM, Hoogendam JP, Raaijmakers AJ et al. (2015) Boosting SNR with an internal antenna and external antennae in the human cervix uteri in TSE at 7 T. Available at http://www.ismrm.org/14/program_files/EP05.htm. Accessed 27 November 2015
deSouza NM, McIndoe GA, Soutter WP et al (1998) Value of magnetic resonance imaging with an endovaginal receiver coil in the pre-operative assessment of Stage I and IIa cervical neoplasia. BJOG 105:500–507 CrossRef
Colombo N, Carinelli S, Colombo A, Marini C, Rollo D, Sessa C (2012) Cervical cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Ann Oncol 23(Suppl 7):vii27–vii32 PubMed
- High-resolution T2-weighted cervical cancer imaging: a feasibility study on ultra-high-field 7.0-T MRI with an endorectal monopole antenna
Jacob P. Hoogendam
Irene M. L. Kalleveen
Catalina S. Arteaga de Castro
Alexander J. E. Raaijmakers
René H. M. Verheijen
Maurice A. A. J. van den Bosch
Dennis W. J. Klomp
Ronald P. Zweemer
Wouter B. Veldhuis
- Springer Berlin Heidelberg
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