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Erschienen in: The journal of nutrition, health & aging 8/2019

24.06.2019

Higher Vitamin D Levels are Associated with Better Attentional Functions: Data from the NorCog Register

verfasst von: J. Zugic Soares, R. Pettersen, J. Saltyte Benth, A. B. Knapskog, G. Selbæk, N. Bogdanovic

Erschienen in: The journal of nutrition, health & aging | Ausgabe 8/2019

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Abstract

Objectives

The aim of this cross-sectional study was to evaluate which cognitive domains are mostly affected in persons with vitamin D insufficiency or deficiency, defined as 25(OH)D < 50 nmol/l and < 25 nmol/l, respectively.

Methods

Data were collected from the Norwegian register for persons assessed for cognitive symptoms (NorCog). 580 persons aged ≥ 65 years were included. The following cognitive and neuropsychiatric tests were used: Mini Mental State Examination, Norwegian Revised Version (MMSE-NR), the Clock Drawing test, the Trail Making Test A and B, the 10-word memory test and the figure copying test from CERAD — immediate and delayed recall, The Controlled Oral Word Association Test -FAS and Boston Naming test. Neuropsychiatric symptoms were assessed by Neuropsychiatric Inventory—Questionnaire and Cornell Scale for Depression in Dementia.

Results

Vitamin D-insufficiency was found in approx. 30 % of the study cohort. After adjustment for relevant covariates, higher serum 25(OH)D levels were associated with higher score on MMSE-NR (p=0.032) and 10-word Memory Test, immediate recall (p=0.038), as well as faster execution of Trail Making Test A and B (p=0.038 and p=0.021, respectively). Other tests were not significantly associated with 25(OH)D levels.

Conclusion

Higher vitamin D levels appear to be associated with better cognition, especially in areas of executive function and mental flexibility.
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Metadaten
Titel
Higher Vitamin D Levels are Associated with Better Attentional Functions: Data from the NorCog Register
verfasst von
J. Zugic Soares
R. Pettersen
J. Saltyte Benth
A. B. Knapskog
G. Selbæk
N. Bogdanovic
Publikationsdatum
24.06.2019
Verlag
Springer Paris
Erschienen in
The journal of nutrition, health & aging / Ausgabe 8/2019
Print ISSN: 1279-7707
Elektronische ISSN: 1760-4788
DOI
https://doi.org/10.1007/s12603-019-1220-z

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