Skip to main content
Erschienen in: Osteoporosis International 10/2012

01.10.2012 | Original Article

Hip fracture incidence is decreasing in the high incidence area of Oslo, Norway

verfasst von: R. Ø. Støen, L. Nordsletten, H. E. Meyer, J. F. Frihagen, J. A. Falch, C. M. Lofthus

Erschienen in: Osteoporosis International | Ausgabe 10/2012

Einloggen, um Zugang zu erhalten

Abstract

Summary

This study reports a significant decrease in age-adjusted incidence rates of hip fracture for women in Oslo, Norway, even compared with data from 1978/1979. Use of bisphosphonate may explain up to one third of the decline in the incidence.

Introduction

The aims of the present study were to report the current incidence of hip fractures in Oslo and to estimate the influence of bisphosphonates on the current incidence.

Methods

Using the electronic diagnosis registers and lists from the operating theaters of the hospitals of Oslo, all patients with ICD-10 codes S72.0 and S72.1 (hip fracture) in 2007 were identified. Medical records of all identified patients were reviewed to verify the diagnosis. Age- and gender-specific annual incidence rates were calculated using the population of Oslo on January 1, 2007 as the population at risk. Data on the use of bisphosphonates were obtained from official registers.

Results

A total number of 1,005 hip fractures, 712 (71%) in women, were included. The age-adjusted fracture rates per 10,000 for the age group >50 years were 82.0 for women and 39.1 for men in 2007, compared with 110.8 and 41.4 in 1996/1997, 116.5 and 42.9 in 1988/1989, and 97.5 and 34.5 in 1978/1979, respectively. It was estimated that the use of bisphosphonates may explain up to 13% of the decline in incidence in women aged 60–69 years and up to 34% in women aged 70–79 years.

Conclusions

The incidence of hip fractures in women in Oslo has decreased significantly during the last decade and is now at a lower level than in 1978/1979. This reduction was not evident in men. The incidence of hip fractures in Oslo is, however, still the highest in the world.
Literatur
1.
Zurück zum Zitat Osnes EK, Lofthus CM, Meyer HE, Falch JA, Nordsletten L, Cappelen I, Kristiansen IS (2004) Consequences of hip fracture on activities of daily life and residential needs. Osteoporos Int 15:567–574PubMedCrossRef Osnes EK, Lofthus CM, Meyer HE, Falch JA, Nordsletten L, Cappelen I, Kristiansen IS (2004) Consequences of hip fracture on activities of daily life and residential needs. Osteoporos Int 15:567–574PubMedCrossRef
2.
Zurück zum Zitat Lu-Yao GL, Keller RB, Littenberg B, Wennberg JE (1994) Outcomes after displaced fractures of the femoral neck. A meta-analysis of one hundred and six published reports. J Bone Joint Surg Am 76:15–25PubMed Lu-Yao GL, Keller RB, Littenberg B, Wennberg JE (1994) Outcomes after displaced fractures of the femoral neck. A meta-analysis of one hundred and six published reports. J Bone Joint Surg Am 76:15–25PubMed
3.
Zurück zum Zitat Shi N, Foley K, Lenhart G, Badamgarav E (2009) Direct healthcare costs of hip, vertebral, and non-hip, non-vertebral fractures. Bone 45:1084–1090PubMedCrossRef Shi N, Foley K, Lenhart G, Badamgarav E (2009) Direct healthcare costs of hip, vertebral, and non-hip, non-vertebral fractures. Bone 45:1084–1090PubMedCrossRef
4.
Zurück zum Zitat Lofthus CM, Osnes EK, Falch JA, Kaastad TS, Kristiansen IS, Nordsletten L, Stensvold I, Meyer HE (2001) Epidemiology of hip fractures in Oslo, Norway. Bone 29:413–418PubMedCrossRef Lofthus CM, Osnes EK, Falch JA, Kaastad TS, Kristiansen IS, Nordsletten L, Stensvold I, Meyer HE (2001) Epidemiology of hip fractures in Oslo, Norway. Bone 29:413–418PubMedCrossRef
5.
Zurück zum Zitat Leslie WD, O’Donnell S, Jean S, Lagace C, Walsh P, Bancej C, Morin S, Hanley DA, Papaioannou A, for the Osteoporosis Surveillance Expert Working Group (2009) Trends in hip fracture rates in Canada. JAMA 302:883–889PubMedCrossRef Leslie WD, O’Donnell S, Jean S, Lagace C, Walsh P, Bancej C, Morin S, Hanley DA, Papaioannou A, for the Osteoporosis Surveillance Expert Working Group (2009) Trends in hip fracture rates in Canada. JAMA 302:883–889PubMedCrossRef
6.
Zurück zum Zitat Ahlborg HG, Rosengren BE, Jarvinen TL, Rogmark C, Nilsson JA, Sernbo I, Karlsson MK (2010) Prevalence of osteoporosis and incidence of hip fracture in women—secular trends over 30 years. BMC Musculoskelet Disord 11:48PubMedCrossRef Ahlborg HG, Rosengren BE, Jarvinen TL, Rogmark C, Nilsson JA, Sernbo I, Karlsson MK (2010) Prevalence of osteoporosis and incidence of hip fracture in women—secular trends over 30 years. BMC Musculoskelet Disord 11:48PubMedCrossRef
8.
Zurück zum Zitat Lyles KW, Colon-Emeric CS, Magaziner JS, Adachi JD, Pieper CF, Mautalen C, Hyldstrup L, Recknor C, Nordsletten L, Moore KA, Lavecchia C, Zhang J, Mesenbrink P, Hodgson PK, Abrams K, Orloff JJ, Horowitz Z, Eriksen EF, Boonen S (2007) Zoledronic acid and clinical fractures and mortality after hip fracture. N Engl J Med 357:1799–1809PubMedCrossRef Lyles KW, Colon-Emeric CS, Magaziner JS, Adachi JD, Pieper CF, Mautalen C, Hyldstrup L, Recknor C, Nordsletten L, Moore KA, Lavecchia C, Zhang J, Mesenbrink P, Hodgson PK, Abrams K, Orloff JJ, Horowitz Z, Eriksen EF, Boonen S (2007) Zoledronic acid and clinical fractures and mortality after hip fracture. N Engl J Med 357:1799–1809PubMedCrossRef
9.
Zurück zum Zitat Wells GA, Cranney A, Peterson J, Boucher M, Shea B, Robinson V, Coyle D, Tugwell P (2008) Alendronate for the primary and secondary prevention of osteoporotic fractures in postmenopausal women. Cochrane Database Syst Rev CD001155. Wells GA, Cranney A, Peterson J, Boucher M, Shea B, Robinson V, Coyle D, Tugwell P (2008) Alendronate for the primary and secondary prevention of osteoporotic fractures in postmenopausal women. Cochrane Database Syst Rev CD001155.
10.
Zurück zum Zitat Siris ES, Selby PL, Saag KG, Borgstrom F, Herings RM, Silverman SL (2009) Impact of osteoporosis treatment adherence on fracture rates in North America and Europe. Am J Med 122:3–13CrossRef Siris ES, Selby PL, Saag KG, Borgstrom F, Herings RM, Silverman SL (2009) Impact of osteoporosis treatment adherence on fracture rates in North America and Europe. Am J Med 122:3–13CrossRef
11.
Zurück zum Zitat Devold HM, Doung GM, Tverdal A, Furu K, Meyer HE, Falch JA, Sogaard AJ (2010) Prescription of anti-osteoporosis drugs during 2004–2007—a nationwide register study in Norway. Eur J Clin Pharmacol 66:299–306PubMedCrossRef Devold HM, Doung GM, Tverdal A, Furu K, Meyer HE, Falch JA, Sogaard AJ (2010) Prescription of anti-osteoporosis drugs during 2004–2007—a nationwide register study in Norway. Eur J Clin Pharmacol 66:299–306PubMedCrossRef
12.
Zurück zum Zitat Falch JA, Ilebekk A, Slungaard U (1985) Epidemiology of hip fractures in Norway. Acta Orthop Scand 56:12–16PubMedCrossRef Falch JA, Ilebekk A, Slungaard U (1985) Epidemiology of hip fractures in Norway. Acta Orthop Scand 56:12–16PubMedCrossRef
13.
Zurück zum Zitat Falch JA, Kaastad TS, Bohler G, Espeland J, Sundsvold OJ (1993) Secular increase and geographical differences in hip fracture incidence in Norway. Bone 14:643–645PubMedCrossRef Falch JA, Kaastad TS, Bohler G, Espeland J, Sundsvold OJ (1993) Secular increase and geographical differences in hip fracture incidence in Norway. Bone 14:643–645PubMedCrossRef
16.
Zurück zum Zitat Falch JA (1996) Meyer HE [Bone mineral density measured by dual X-ray absorptiometry. A reference material from Oslo]. Tidsskr Nor Laegeforen 116:2299–2302PubMed Falch JA (1996) Meyer HE [Bone mineral density measured by dual X-ray absorptiometry. A reference material from Oslo]. Tidsskr Nor Laegeforen 116:2299–2302PubMed
17.
Zurück zum Zitat Kanis JA, Johnell O, Oden A, Jonsson B, De LC, Dawson A (2000) Risk of hip fracture according to the World Health Organization criteria for osteopenia and osteoporosis. Bone 27:585–590PubMedCrossRef Kanis JA, Johnell O, Oden A, Jonsson B, De LC, Dawson A (2000) Risk of hip fracture according to the World Health Organization criteria for osteopenia and osteoporosis. Bone 27:585–590PubMedCrossRef
18.
Zurück zum Zitat Black DM, Thompson DE, Bauer DC, Ensrud K, Musliner T, Hochberg MC, Nevitt MC, Suryawanshi S, Cummings SR (2000) Fracture risk reduction with alendronate in women with osteoporosis: the Fracture Intervention Trial. FIT Research Group. J Clin Endocrinol Metab 85:4118–4124PubMedCrossRef Black DM, Thompson DE, Bauer DC, Ensrud K, Musliner T, Hochberg MC, Nevitt MC, Suryawanshi S, Cummings SR (2000) Fracture risk reduction with alendronate in women with osteoporosis: the Fracture Intervention Trial. FIT Research Group. J Clin Endocrinol Metab 85:4118–4124PubMedCrossRef
19.
Zurück zum Zitat Armitage P, Berry G (1994) Statistical methods in medical research. Armitage P, Berry G (1994) Statistical methods in medical research.
20.
Zurück zum Zitat Icks A, Haastert B, Wildner M, Becker C, Meyer G (2008) Hip fracture incidence in Germany: analysis of the national hospital discharge registry 2004. Dtsch Med Wochenschr 133:125–128PubMedCrossRef Icks A, Haastert B, Wildner M, Becker C, Meyer G (2008) Hip fracture incidence in Germany: analysis of the national hospital discharge registry 2004. Dtsch Med Wochenschr 133:125–128PubMedCrossRef
21.
Zurück zum Zitat Holt G, Smith R, Duncan K, Hutchison JD, Gregori A (2008) Gender differences in epidemiology and outcome after hip fracture: evidence from the Scottish Hip Fracture Audit. J Bone Joint Surg Br 90:480–483PubMedCrossRef Holt G, Smith R, Duncan K, Hutchison JD, Gregori A (2008) Gender differences in epidemiology and outcome after hip fracture: evidence from the Scottish Hip Fracture Audit. J Bone Joint Surg Br 90:480–483PubMedCrossRef
22.
Zurück zum Zitat Moayyeri A, Soltani A, Larijani B, Naghavi M, Alaeddini F, Abolhassani F (2006) Epidemiology of hip fracture in Iran: results from the Iranian multicenter study on accidental injuries. Osteoporos Int 17:1252–1257PubMedCrossRef Moayyeri A, Soltani A, Larijani B, Naghavi M, Alaeddini F, Abolhassani F (2006) Epidemiology of hip fracture in Iran: results from the Iranian multicenter study on accidental injuries. Osteoporos Int 17:1252–1257PubMedCrossRef
23.
Zurück zum Zitat El MA, Koumba BA, Jroundi I, Achemlal L, Bezza A, Tazi MA (2005) Epidemiology of hip fractures in 2002 in Rabat, Morocco. Osteoporos Int 16:597–602CrossRef El MA, Koumba BA, Jroundi I, Achemlal L, Bezza A, Tazi MA (2005) Epidemiology of hip fractures in 2002 in Rabat, Morocco. Osteoporos Int 16:597–602CrossRef
24.
Zurück zum Zitat Hagino H, Katagiri H, Okano T, Yamamoto K, Teshima R (2005) Increasing incidence of hip fracture in Tottori Prefecture, Japan: trend from 1986 to 2001. Osteoporos Int 16:1963–1968PubMedCrossRef Hagino H, Katagiri H, Okano T, Yamamoto K, Teshima R (2005) Increasing incidence of hip fracture in Tottori Prefecture, Japan: trend from 1986 to 2001. Osteoporos Int 16:1963–1968PubMedCrossRef
25.
Zurück zum Zitat Soveid M, Serati AR, Masoompoor M (2005) Incidence of hip fracture in Shiraz, Iran. Osteoporos Int 16:1412–1416PubMedCrossRef Soveid M, Serati AR, Masoompoor M (2005) Incidence of hip fracture in Shiraz, Iran. Osteoporos Int 16:1412–1416PubMedCrossRef
26.
Zurück zum Zitat de Pina MF, Alves SM, Barbosa M, Barros H (2008) Hip fractures cluster in space: an epidemiological analysis in Portugal. Osteoporos Int 19:1797–1804PubMedCrossRef de Pina MF, Alves SM, Barbosa M, Barros H (2008) Hip fractures cluster in space: an epidemiological analysis in Portugal. Osteoporos Int 19:1797–1804PubMedCrossRef
27.
Zurück zum Zitat Chie WC, Yang RS, Liu JP, Tsai KS (2004) High incidence rate of hip fracture in Taiwan: estimated from a nationwide health insurance database. Osteoporos Int 15:998–1002PubMedCrossRef Chie WC, Yang RS, Liu JP, Tsai KS (2004) High incidence rate of hip fracture in Taiwan: estimated from a nationwide health insurance database. Osteoporos Int 15:998–1002PubMedCrossRef
28.
Zurück zum Zitat Abolhassani F, Moayyeri A, Naghavi M, Soltani A, Larijani B, Shalmani HT (2006) Incidence and characteristics of falls leading to hip fracture in Iranian population. Bone 39:408–413PubMedCrossRef Abolhassani F, Moayyeri A, Naghavi M, Soltani A, Larijani B, Shalmani HT (2006) Incidence and characteristics of falls leading to hip fracture in Iranian population. Bone 39:408–413PubMedCrossRef
29.
Zurück zum Zitat Kannus P, Parkkari J, Niemi S, Pasanen M, Palvanen M, Jarvinen M, Vuori I (2000) Prevention of hip fracture in elderly people with use of a hip protector. N Engl J Med 343:1506–1513PubMedCrossRef Kannus P, Parkkari J, Niemi S, Pasanen M, Palvanen M, Jarvinen M, Vuori I (2000) Prevention of hip fracture in elderly people with use of a hip protector. N Engl J Med 343:1506–1513PubMedCrossRef
30.
Zurück zum Zitat Gale CR, Martyn CN, Kellingray S, Eastell R, Cooper C (2001) Intrauterine programming of adult body composition. J Clin Endocrinol Metab 86:267–272PubMedCrossRef Gale CR, Martyn CN, Kellingray S, Eastell R, Cooper C (2001) Intrauterine programming of adult body composition. J Clin Endocrinol Metab 86:267–272PubMedCrossRef
31.
Zurück zum Zitat Droyvold WB, Nilsen TI, Kruger O, Holmen TL, Krokstad S, Midthjell K, Holmen J (2006) Change in height, weight and body mass index: longitudinal data from the HUNT study in Norway. Int J Obes (Lond) 30:935–939CrossRef Droyvold WB, Nilsen TI, Kruger O, Holmen TL, Krokstad S, Midthjell K, Holmen J (2006) Change in height, weight and body mass index: longitudinal data from the HUNT study in Norway. Int J Obes (Lond) 30:935–939CrossRef
32.
Zurück zum Zitat Statistics Norway, NSD. National health survey 2008. 2009; NSD1327. Statistics Norway, NSD. National health survey 2008. 2009; NSD1327.
33.
Zurück zum Zitat Statistics Norway, NSD. National health survey 1998. 2009; NSD0415. Statistics Norway, NSD. National health survey 1998. 2009; NSD0415.
34.
Zurück zum Zitat Michaelsson K, Baron JA, Farahmand BY, Johnell O, Magnusson C, Persson PG, Persson I, Ljunghall S (1998) Hormone replacement therapy and risk of hip fracture: population based case–control study. BMJ 316:1858–1863PubMedCrossRef Michaelsson K, Baron JA, Farahmand BY, Johnell O, Magnusson C, Persson PG, Persson I, Ljunghall S (1998) Hormone replacement therapy and risk of hip fracture: population based case–control study. BMJ 316:1858–1863PubMedCrossRef
35.
Zurück zum Zitat Meyer HE, Lofthus CM, Sogaard AJ, Falch JA (2008) Change in the use of hormone replacement therapy and the incidence of fracture in Oslo. Osteoporos Int 5:827–830 Meyer HE, Lofthus CM, Sogaard AJ, Falch JA (2008) Change in the use of hormone replacement therapy and the incidence of fracture in Oslo. Osteoporos Int 5:827–830
36.
Zurück zum Zitat Lofthus CM, Frihagen F, Meyer HE, Nordsletten L, Melhuus K, Falch JA (2008) Epidemiology of distal forearm fractures in Oslo, Norway. Osteoporos Int 19:781–786PubMedCrossRef Lofthus CM, Frihagen F, Meyer HE, Nordsletten L, Melhuus K, Falch JA (2008) Epidemiology of distal forearm fractures in Oslo, Norway. Osteoporos Int 19:781–786PubMedCrossRef
37.
Zurück zum Zitat Cheng SY, Levy AR, Lefaivre KA, Guy P, Kuramoto L, Sobolev B (2011) Geographic trends in incidence of hip fractures: a comprehensive literature review. Osteoporos Int 10:2575–2586CrossRef Cheng SY, Levy AR, Lefaivre KA, Guy P, Kuramoto L, Sobolev B (2011) Geographic trends in incidence of hip fractures: a comprehensive literature review. Osteoporos Int 10:2575–2586CrossRef
38.
Zurück zum Zitat Brauer CA, Coca-Perraillon M, Cutler DM, Rosen AB (2009) Incidence and mortality of hip fractures in the United States. JAMA 302:1573–1579PubMedCrossRef Brauer CA, Coca-Perraillon M, Cutler DM, Rosen AB (2009) Incidence and mortality of hip fractures in the United States. JAMA 302:1573–1579PubMedCrossRef
39.
Zurück zum Zitat Lofthus CM, Cappelen I, Osnes EK, Falch JA, Kristiansen IS, Medhus AW, Nordsletten L, Meyer HE (2005) Local and national electronic databases in Norway demonstrate a varying degree of validity. J Clin Epidemiol 58:280–285PubMedCrossRef Lofthus CM, Cappelen I, Osnes EK, Falch JA, Kristiansen IS, Medhus AW, Nordsletten L, Meyer HE (2005) Local and national electronic databases in Norway demonstrate a varying degree of validity. J Clin Epidemiol 58:280–285PubMedCrossRef
Metadaten
Titel
Hip fracture incidence is decreasing in the high incidence area of Oslo, Norway
verfasst von
R. Ø. Støen
L. Nordsletten
H. E. Meyer
J. F. Frihagen
J. A. Falch
C. M. Lofthus
Publikationsdatum
01.10.2012
Verlag
Springer-Verlag
Erschienen in
Osteoporosis International / Ausgabe 10/2012
Print ISSN: 0937-941X
Elektronische ISSN: 1433-2965
DOI
https://doi.org/10.1007/s00198-011-1888-3

Weitere Artikel der Ausgabe 10/2012

Osteoporosis International 10/2012 Zur Ausgabe

Arthropedia

Grundlagenwissen der Arthroskopie und Gelenkchirurgie. Erweitert durch Fallbeispiele, Videos und Abbildungen. 
» Jetzt entdecken

Update Orthopädie und Unfallchirurgie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.