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Erschienen in: Die Pathologie 1/2022

29.09.2022 | Hauptreferate: Hauptprogramm der DGP

Histiocytic and dendritic cell neoplasms

verfasst von: Prof. Dr. Dr. h.c. Stefano A. Pileri, Federica Melle, BS, PhD, Giovanna Motta, BS, PhD, Valentina Tabanelli, MD

Erschienen in: Die Pathologie | Sonderheft 1/2022

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Abstract

Background

Histiocytic and dendritic cell neoplasms (HDCNs) represent very rare tumors, which have been the subject of debate during the last few years.

Objectives

We aimed to provide a comprehensive review of the subject.

Materials and methods

The experience gained by the authors in large international studies and as a national reference center has been summarized to highlight the characteristics of each entity.

Results

The clinical, morphologic, phenotypic, and molecular data of the different entities included under the heading of HDCNs are extensively discussed.

Conclusion

Currently, HDCNs are classified in the group of orphan diseases for which a standardized therapy is lacking. An international registry would facilitate expansion and dissemination of knowledge of these diseases and improve their treatment.
Literatur
1.
Zurück zum Zitat Pileri SA, Grogan TM, Harris NL et al (2002) Tumors of histiocytes and accessory dendritic cells: an immunohistochemical approach to classification from the International Lymphoma Study Group based on 61 cases. Histopathology 41:1–29CrossRef Pileri SA, Grogan TM, Harris NL et al (2002) Tumors of histiocytes and accessory dendritic cells: an immunohistochemical approach to classification from the International Lymphoma Study Group based on 61 cases. Histopathology 41:1–29CrossRef
2.
Zurück zum Zitat Facchetti F, Pileri SA, Lorenzi L et al (2017) Histiocytic and dendritic cell neoplasms: what have we learnt by studying 67 cases. Virchows Arch 471:467–489CrossRef Facchetti F, Pileri SA, Lorenzi L et al (2017) Histiocytic and dendritic cell neoplasms: what have we learnt by studying 67 cases. Virchows Arch 471:467–489CrossRef
3.
Zurück zum Zitat Swerdlow SH, Campo E, Harris NL, Jaffe ES, Pileri SA, Stein H, Thiele J (2017) WHO classification of tumour of haematopoietic and lymphoid tissues, 4th edn. IARC Press, Lyon Swerdlow SH, Campo E, Harris NL, Jaffe ES, Pileri SA, Stein H, Thiele J (2017) WHO classification of tumour of haematopoietic and lymphoid tissues, 4th edn. IARC Press, Lyon
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Zurück zum Zitat Alaggio R, Amador C, Anagnostopoulos I et al (2022) The 5th edition of the World Health Organization classification of haematolymphoid tumours: lymphoid neoplasms. Leukemia 36:1703–1719CrossRef Alaggio R, Amador C, Anagnostopoulos I et al (2022) The 5th edition of the World Health Organization classification of haematolymphoid tumours: lymphoid neoplasms. Leukemia 36:1703–1719CrossRef
Metadaten
Titel
Histiocytic and dendritic cell neoplasms
verfasst von
Prof. Dr. Dr. h.c. Stefano A. Pileri
Federica Melle, BS, PhD
Giovanna Motta, BS, PhD
Valentina Tabanelli, MD
Publikationsdatum
29.09.2022
Verlag
Springer Medizin
Erschienen in
Die Pathologie / Ausgabe Sonderheft 1/2022
Print ISSN: 2731-7188
Elektronische ISSN: 2731-7196
DOI
https://doi.org/10.1007/s00292-022-01116-x

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