Erschienen in:
08.07.2018 | Original Article
Histological changes secondary to wire coil placement in breast tissue and lymph nodes
verfasst von:
Ignacio Pinilla-Pagnon, Belén Pérez-Mies, María Eugenia Reguero, Marco-Tulio Martinez, Miguel Chiva, Silvia Pérez-Rodrigo, Odile Ajuria Illarramendi, Maria Eugenia Rioja Martin, Maria Vicenta Collado, Maria Concepción Sanchez, Juan Manuel Rosa-Rosa, José Palacios
Erschienen in:
Virchows Archiv
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Ausgabe 3/2018
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Abstract
We describe the histological and immunohistochemical features of the changes produced by spiral coil localization wires in the breast parenchyma and lymph nodes of a total of 100 patients undergoing surgery for different breast lesions. Coil wires produced cystic lesions containing a hyaline, mucous-like, PAS-negative fluid. Cavities were lined by cells of variable morphology ranging from synovial-like cells (with a conspicuous epithelial appearance) to mononuclear or multinucleate histiocytic cells that expressed CD68, but were negative for keratins. CD3-positive/CD8-positive T lymphocytes predominated in the inflammatory reaction. Pathologists should be aware of these changes in order to differentiate coil-related lesions from other granulomatous or epithelial lesions, including mucocele-like and ductal carcinoma in situ lesions.