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International Journal of Legal Medicine
Erschienen in:

19.10.2017 | Case Report

Histological criteria for age determination of fatal venous thromboembolism

verfasst von: Valeria Maffeis, Lorenzo Nicolè, Claudio Rago, Ambrogio Fassina

Erschienen in: International Journal of Legal Medicine | Ausgabe 3/2018

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Abstract

In clinical and forensic practice, fatal thromboembolism is a major problem, particularly in a patient with no pre-existing risk factors. Out of a recent case, we discuss here the criteria for age determination of venous thrombi in a 46-year-old female with concomitant deep vein thrombosis in the common femoral left vein and in the right heart and fatal pulmonary embolism. At autopsy, histopathology and immunohistochemistry evidenced the different composition of thrombi in different sites and permitted to define the different timing. We discuss and review the histopathological criteria for age estimation of venous thrombi starting from the case and in relation to the acquired and inherited thrombophilic risk factors. The appropriateness of clinical management is also discussed.
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Metadaten
Titel
Histological criteria for age determination of fatal venous thromboembolism
verfasst von
Valeria Maffeis
Lorenzo Nicolè
Claudio Rago
Ambrogio Fassina
Publikationsdatum
19.10.2017
Verlag
Springer Berlin Heidelberg
Erschienen in
International Journal of Legal Medicine / Ausgabe 3/2018
Print ISSN: 0937-9827
Elektronische ISSN: 1437-1596
DOI
https://doi.org/10.1007/s00414-017-1705-4

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