Erschienen in:
14.12.2017 | Case Report
HIV-associated opsoclonus-myoclonus-ataxia syndrome: early infection, immune reconstitution syndrome or secondary to other diseases? Case report and literature review
verfasst von:
Bruno F. Guedes, Márcio A. A. Vieira Filho, Clarice Listik, Rafael B. Carra, Cristiane B. Pereira, Emanuelle R. da Silva, Hélio R. Gomes, José E. Vidal
Erschienen in:
Journal of NeuroVirology
|
Ausgabe 1/2018
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Abstract
Opsoclonus-myoclonus-ataxia (OMA) syndrome is a debilitating autoimmune neurological disorder. Post-infectious opsoclonus-myoclonus-ataxia syndrome has been described with varying bacterial, spirochetal, and viral infections including several patients with HIV. However, specific immunopathological mechanisms that may lead to opsoclonus-myoclonus in HIV-positive patients are unknown.
We report a case of HIV-associated opsoclonus-myoclonus and early HIV infection. A review of published literature shows opsoclonus-myoclonus can occur during early infection, in immune reconstitution syndrome or in association with other infections, especially tuberculosis.