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01.12.2015 | Study protocol | Ausgabe 1/2015 Open Access

BMC Musculoskeletal Disorders 1/2015

HOPE-trial: hemiarthroplasty compared to total hip arthroplasty for displaced femoral neck fractures in the elderly-elderly, a randomized controlled trial

BMC Musculoskeletal Disorders > Ausgabe 1/2015
Olof Sköldenberg, Ghazi Chammout, Sebastian Mukka, Olle Muren, Hans Nåsell, Carl-Johan Hedbeck, Mats Salemyr
Wichtige Hinweise

Competing interest

The authors declare that they have no competing interests.

Authors’ contributions

OS initiated the study, designed the study, wrote the manuscript, supervised GC and SM and is the principal investigator of the study. GC initiated the study, designed the study and wrote the manuscript. SM wrote the first draft of the manuscript. MS and OM helped design the study and wrote the manuscript. HS and C-JH wrote the manuscript. All authors read and approved the final manuscript.



A femoral neck fracture (FNF) is a common cause of suffering and premature death in the elderly population. Optimizing the treatment for improved outcome and a reduced need for secondary surgery is important both for the patient and the society. The choice of primary total or hemiarthroplasty in patients over eighty years are controversial. We hypothesized that total hip arthroplasty has an equal or better outcome in patient-reported outcome compared with hemiarthroplasty.


A prospective, randomized, single-blinded trial will be conducted. We will include 120 patients, 80 years of age and over with an acute (<36 h) displaced femoral neck fracture. The patients will be randomized in a 1:1 ratio to either total hip arthroplasty or hemiarthroplasty. The primary endpoints are Harris hip Score and EQ-5D. Secondary endpoints include pain measured with visual analogue scale, surgical time, reoperations, complications and radiological measurement of erosion in patients operated with hemiarthroplasty. Follow-up will be performed postoperatively after three months, 1, 2, 4 and 10 years.


To our knowledge, this is the first randomized controlled trial comparing total hip arthroplasty and hemiarthroplasty for displaced femoral neck fracture in patients age 80 years and over.

Trial registration NCT02246335
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