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Hormones and Cancer

Hormones and Cancer OnlineFirst articles


Prevalence of Histological Characteristics of Breast Cancer in Rwanda in Relation to Age and Tumor Stages

Breast cancer is a complex disease, and it is the most common cause of morbidity and mortality among women worldwide. In Sub-Saharan Africa, the clinical characteristics and tumor profiles of breast cancer are still unknown. In the present study …

05.08.2020 | Original Paper

Outcome of Clinical Genetic Testing in Patients with Features Suggestive for Hereditary Predisposition to PTH-Mediated Hypercalcemia

Primary hyperparathyroidism (pHPT) is associated with familial syndromes such as multiple endocrine neoplasia type 1 (MEN1), 2A (MEN2A), MEN-like syndromes (CDKN1B), and CDC73-related disorder (hyperparathyroidism – jaw tumor syndrome (HPJT)).

06.07.2020 | Original Paper

Nuclear PDCD4 Expression Defines a Subset of Luminal B-Like Breast Cancers with Good Prognosis

The hormone receptor-positive (estrogen and/or progesterone receptor (PR)-positive) and HER2-negative breast cancer (BC) subtype is a biologically heterogeneous entity that includes luminal A-like (LumA-like) and luminal B-like (LumB-like) …

17.06.2020 | Review

The Thyroid Tumor Microenvironment: Potential Targets for Therapeutic Intervention and Prognostication

Thyroid cancer is the most common endocrine malignancy and incidences are rising rapidly, in both pediatric and adult populations. Many thyroid tumors are successfully treated which results in low mortality rates, but there is often a significant …

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Major areas of interest in cancer biology include:

-Cancer causation, metabolism, and hormone-dependence

-Disease progression, prevention, treatment, and resistance

-Translational studies dealing with novel therapeutic agents

-Hormone receptors and their co-regulatory molecules

-Hormonally infl uenced signaling pathways

-Nuclear and Steroid Hormone Receptors

-Adrenal, pituitary, and thyroid hormones

-Vitamin D

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