Skip to main content
Erschienen in: Journal of General Internal Medicine 10/2008

01.10.2008 | Original Article

How Do Community Practitioners Decide Whether to Prescribe Antibiotics for Acute Respiratory Tract Infections?

verfasst von: Robert S. Wigton, MD, MS, Carol A. Darr, PhD, Kitty K. Corbett, PhD, MPH, Devin R. Nickol, MD, Ralph Gonzales, MD, MSPH

Erschienen in: Journal of General Internal Medicine | Ausgabe 10/2008

Einloggen, um Zugang zu erhalten

Abstract

BACKGROUND

Overuse of antibiotics in the treatment of acute respiratory tract infection (ARI) contributes to the growing problem of antibiotic-resistant infections.

OBJECTIVE

To identify factors that influence community practitioners to prescribe antibiotics and examine how they differ from the recommendations of the Centers for Disease Control and Prevention (CDC) guideline for treatment of ARI.

DESIGN

Paper case vignette study using a fractional factorial design.

PARTICIPANTS

One hundred one community practitioners and eight faculty members.

MAIN MEASUREMENTS

We asked community practitioners to estimate how likely they would be to prescribe antibiotics in each of 20 cases of ARI and then used multiple regression to infer the importance weights of each of nine clinical findings. We then compared practitioners’ weights with those of a panel of eight faculty physicians who evaluated the cases following the CDC guidelines rather than their own judgments.

MAIN RESULTS

Practitioners prescribed antibiotics in 44.5% of cases, over twice the percentage treated by the panel using the CDC guidelines (20%). In deciding to prescribe antibiotic treatment, practitioners gave little or no weight to patient factors such as whether the patients wanted antibiotics. Although weighting patterns differed among practitioners, the majority (72%) gave the greatest weight to duration of illness. When illness duration was short, the rate of prescribing (20.1%) was the same as the rate of the faculty panel (20%).

CONCLUSIONS

Based on hypothetical cases of ARI, community practitioners prescribed antibiotics at twice the rate of faculty following CDC practice guidelines. Practitioners were most strongly influenced by duration of illness. The effect of duration was strongest when accompanied by fever or productive cough, suggesting that these situations would be important areas for practitioner education and further clinical studies.
Anhänge
Nur mit Berechtigung zugänglich
Literatur
1.
Zurück zum Zitat Roumie CL, Halasa NB, Grijalva CG, Edwards KM, Zhu Y, Dittus RS, Griffin MR. Trends in antibiotic prescribing for adults in the United States-1995 to 2002. J Gen Intern Med. 2005;20:697–702.PubMedCrossRef Roumie CL, Halasa NB, Grijalva CG, Edwards KM, Zhu Y, Dittus RS, Griffin MR. Trends in antibiotic prescribing for adults in the United States-1995 to 2002. J Gen Intern Med. 2005;20:697–702.PubMedCrossRef
2.
Zurück zum Zitat Gonzales R, Barrett PH Jr, Crane LA, Steiner JF. Factors associated with antibiotic use for acute bronchitis. J Gen Intern Med. 1998;13(8)541–8. Aug.PubMedCrossRef Gonzales R, Barrett PH Jr, Crane LA, Steiner JF. Factors associated with antibiotic use for acute bronchitis. J Gen Intern Med. 1998;13(8)541–8. Aug.PubMedCrossRef
3.
Zurück zum Zitat Gonzales R, Barrett PH, Steiner JF. The relation between purulent manifestations and antibiotic treatment of upper respiratory tract infections. J Gen Intern Med. 1999;14:151–6.PubMedCrossRef Gonzales R, Barrett PH, Steiner JF. The relation between purulent manifestations and antibiotic treatment of upper respiratory tract infections. J Gen Intern Med. 1999;14:151–6.PubMedCrossRef
4.
Zurück zum Zitat Macfarlane J, Holmes W, Macfarlane R, Britten N. Influence of patients’ expectations on antibiotic management of acute lower respiratory tract illness in general practice: questionnaire study. BMJ. 1997;315(7117)1211–4. Nov 8.PubMed Macfarlane J, Holmes W, Macfarlane R, Britten N. Influence of patients’ expectations on antibiotic management of acute lower respiratory tract illness in general practice: questionnaire study. BMJ. 1997;315(7117)1211–4. Nov 8.PubMed
5.
Zurück zum Zitat Scott JG, Cohen D, DiCicco-Bloom B, Orzano AJ, Jaen CR, Crabtree BF. Antibiotic use in acute respiratory infections and the ways patients pressure physicians for a prescription. J Fam Pract. 2001;50(10)853–8. Oct, Erratum in: J Fam Pract 2001 Dec;50(12):1077.PubMed Scott JG, Cohen D, DiCicco-Bloom B, Orzano AJ, Jaen CR, Crabtree BF. Antibiotic use in acute respiratory infections and the ways patients pressure physicians for a prescription. J Fam Pract. 2001;50(10)853–8. Oct, Erratum in: J Fam Pract 2001 Dec;50(12):1077.PubMed
6.
Zurück zum Zitat Steinman MA, Landefeld CS, Gonzales R. Predictors of broad-spectrum antibiotic prescribing for acute respiratory tract infections in adult primary care. JAMA. 2003;289:719–25.PubMedCrossRef Steinman MA, Landefeld CS, Gonzales R. Predictors of broad-spectrum antibiotic prescribing for acute respiratory tract infections in adult primary care. JAMA. 2003;289:719–25.PubMedCrossRef
7.
Zurück zum Zitat Little DR, Mann PL, Godbout CJ. How family physicians distinguish acute sinusitis from upper respiratory tract infection: a retrospective analysis. J Am Board Fam Pract. 2000;13:101–6.PubMed Little DR, Mann PL, Godbout CJ. How family physicians distinguish acute sinusitis from upper respiratory tract infection: a retrospective analysis. J Am Board Fam Pract. 2000;13:101–6.PubMed
8.
Zurück zum Zitat Williams JW, Simel DL. Does this patient have sinusitis? Diagnosing acute sinusitis by history and physical examination. JAMA. 1993;270:1242–6.PubMedCrossRef Williams JW, Simel DL. Does this patient have sinusitis? Diagnosing acute sinusitis by history and physical examination. JAMA. 1993;270:1242–6.PubMedCrossRef
9.
Zurück zum Zitat Dosh SA, Hickner JM, Mainous AG, Ebell MH. Predictors of antibiotic prescribing for nonspecific upper respiratory infections, acute bronchitis, and acute sinusitis. An UPRNet study. Upper Peninsula Research Network. J Fam Pract. 2000;49(5)407–14. May.PubMed Dosh SA, Hickner JM, Mainous AG, Ebell MH. Predictors of antibiotic prescribing for nonspecific upper respiratory infections, acute bronchitis, and acute sinusitis. An UPRNet study. Upper Peninsula Research Network. J Fam Pract. 2000;49(5)407–14. May.PubMed
10.
Zurück zum Zitat Sorum PC, Stewart TR, Mullet E, et al. Does choosing a treatment depend on making a diagnosis? US and French physicians’ decision making about acute otitis media. Med Decis Making. 2002;22(5)394–402. Sep-Oct.PubMedCrossRef Sorum PC, Stewart TR, Mullet E, et al. Does choosing a treatment depend on making a diagnosis? US and French physicians’ decision making about acute otitis media. Med Decis Making. 2002;22(5)394–402. Sep-Oct.PubMedCrossRef
11.
Zurück zum Zitat Wigton RS, Poses RM, Collins M, Cebul RD. Teaching old dogs new tricks: using cognitive feedback to improve physicians’ diagnostic judgments on simulated cases. Acad Med. 1990;65(9)S5–6.PubMedCrossRef Wigton RS, Poses RM, Collins M, Cebul RD. Teaching old dogs new tricks: using cognitive feedback to improve physicians’ diagnostic judgments on simulated cases. Acad Med. 1990;65(9)S5–6.PubMedCrossRef
12.
Zurück zum Zitat Gonzalez-Vallejo C, Sorum PC, Stewart TR, Chessare JB, Mumpower JL. Physicians’ diagnostic judgments and treatment decisions for acute otitis media in children. Med Decis. 12. Gonzalez-Vallejo C, Sorum PC, Stewart TR, Chessare JB, Mumpower JL. Physicians’ diagnostic judgments and treatment decisions for acute otitis media in children. Med Decis. 12.
13.
Zurück zum Zitat Murray S, Del Mar C, O’Rourke P. Predictors of an antibiotic prescription by GP’s for respiratory tract infections: a pilot. Fam Pract. 2000;17:386–8.PubMedCrossRef Murray S, Del Mar C, O’Rourke P. Predictors of an antibiotic prescription by GP’s for respiratory tract infections: a pilot. Fam Pract. 2000;17:386–8.PubMedCrossRef
14.
Zurück zum Zitat Linder JA, Singer DE. Desire for antibiotics and antibiotic prescribing for adults with upper respiratory tract infections. J Gen Intern Med. 2003;18(10)795–801. Oct.PubMedCrossRef Linder JA, Singer DE. Desire for antibiotics and antibiotic prescribing for adults with upper respiratory tract infections. J Gen Intern Med. 2003;18(10)795–801. Oct.PubMedCrossRef
15.
Zurück zum Zitat Butler CC, Rollnick S, Pill R, Maggs-Rapport F, Stott N. Understanding the culture of prescribing: qualitative study of general practitioners’ and patients’ perceptions of antibiotics for sore throats. BMJ. 1998;317(7159)637–42. Sep 5.PubMed Butler CC, Rollnick S, Pill R, Maggs-Rapport F, Stott N. Understanding the culture of prescribing: qualitative study of general practitioners’ and patients’ perceptions of antibiotics for sore throats. BMJ. 1998;317(7159)637–42. Sep 5.PubMed
16.
Zurück zum Zitat Avorn J, Soumerai SB. Improving drug-therapy decisions through educational outreach. A randomized controlled trial of academically based “detailing”. N Engl J Med. 1983;308:1457–63.PubMed Avorn J, Soumerai SB. Improving drug-therapy decisions through educational outreach. A randomized controlled trial of academically based “detailing”. N Engl J Med. 1983;308:1457–63.PubMed
17.
Zurück zum Zitat Plackett RL, Burman JP. The design of optimum multifactorial experiments. Biometrika. 1946;33:305–25.CrossRef Plackett RL, Burman JP. The design of optimum multifactorial experiments. Biometrika. 1946;33:305–25.CrossRef
18.
Zurück zum Zitat Gonzales R, Corbett KK, Leeman-Castillo BA, et al. The “minimizing antibiotic resistance in Colorado” project: impact of patient education in improving antibiotic use in private office practices. Health Serv Res. 2005;40(1)101–16. Feb.PubMedCrossRef Gonzales R, Corbett KK, Leeman-Castillo BA, et al. The “minimizing antibiotic resistance in Colorado” project: impact of patient education in improving antibiotic use in private office practices. Health Serv Res. 2005;40(1)101–16. Feb.PubMedCrossRef
19.
Zurück zum Zitat Gonzales R, Bartlett JG, Besser RE, et al. Principles of appropriate antibiotic use for treatment of acute respiratory tract infections in adults: background, specific aims, and methods. Ann Intern Med. 2001;134(6)479–86. Mar 20.PubMed Gonzales R, Bartlett JG, Besser RE, et al. Principles of appropriate antibiotic use for treatment of acute respiratory tract infections in adults: background, specific aims, and methods. Ann Intern Med. 2001;134(6)479–86. Mar 20.PubMed
20.
Zurück zum Zitat Gonzales R, Bartlett JG, Besser RE, et al. Principles of appropriate antibiotic use for treatment of uncomplicated acute bronchitis: background. Ann Intern Med. 2001;134(6)521–9. Mar 20.PubMed Gonzales R, Bartlett JG, Besser RE, et al. Principles of appropriate antibiotic use for treatment of uncomplicated acute bronchitis: background. Ann Intern Med. 2001;134(6)521–9. Mar 20.PubMed
21.
Zurück zum Zitat Hickner JM, Bartlett JG, Besser RE, et al. Principles of appropriate antibiotic use for acute rhinosinusitis in adults: background. Ann Intern Med. 2001;134(6)498–505. Mar 20.PubMed Hickner JM, Bartlett JG, Besser RE, et al. Principles of appropriate antibiotic use for acute rhinosinusitis in adults: background. Ann Intern Med. 2001;134(6)498–505. Mar 20.PubMed
22.
Zurück zum Zitat Cooksey RW. Judgment Analysis: Theory, Methods, and Applications. Academic Press; 1996. Cooksey RW. Judgment Analysis: Theory, Methods, and Applications. Academic Press; 1996.
23.
Zurück zum Zitat Wigton RS. Use of linear models to analyze physicians’ decisions. Journal of Medical Decision Making. 1988;8:241–52.CrossRef Wigton RS. Use of linear models to analyze physicians’ decisions. Journal of Medical Decision Making. 1988;8:241–52.CrossRef
24.
Zurück zum Zitat Ward JI, Cherry JD, Chang SJ, et al. Efficacy of an acellular pertussis vaccine among adolescents and adults. N Engl J Med. 2005;353(15)1555–63. Oct 13.PubMedCrossRef Ward JI, Cherry JD, Chang SJ, et al. Efficacy of an acellular pertussis vaccine among adolescents and adults. N Engl J Med. 2005;353(15)1555–63. Oct 13.PubMedCrossRef
25.
Zurück zum Zitat Heckerling PS, Tape TG, Wigton RS, et al. Clinical prediction rule for pulmonary infiltrates. Ann Intern Med. 1990;113:664–70.PubMed Heckerling PS, Tape TG, Wigton RS, et al. Clinical prediction rule for pulmonary infiltrates. Ann Intern Med. 1990;113:664–70.PubMed
26.
Zurück zum Zitat Metlay JP, Kapoor WN, Fine MJ. Does this patient have community-acquired pneumonia? Diagnosing pneumonia by history and physical examination. JAMA. 1997;278(17)1440–5. Nov 5.PubMedCrossRef Metlay JP, Kapoor WN, Fine MJ. Does this patient have community-acquired pneumonia? Diagnosing pneumonia by history and physical examination. JAMA. 1997;278(17)1440–5. Nov 5.PubMedCrossRef
27.
Zurück zum Zitat Diehr P, Wood RW, Bushyhead J, Krueger L, Wolcott B, Tompkins RK. Prediction of pneumonia in outpatients with acute cough-a statistical approach. J Chronic Dis. 1984;37(3)215–25.PubMedCrossRef Diehr P, Wood RW, Bushyhead J, Krueger L, Wolcott B, Tompkins RK. Prediction of pneumonia in outpatients with acute cough-a statistical approach. J Chronic Dis. 1984;37(3)215–25.PubMedCrossRef
28.
Zurück zum Zitat Wenzel RP, Fowler AA. Clinical practice. Acute bronchitis. N Engl J Med. 2006;355(20)2125–30. 16.PubMedCrossRef Wenzel RP, Fowler AA. Clinical practice. Acute bronchitis. N Engl J Med. 2006;355(20)2125–30. 16.PubMedCrossRef
29.
Zurück zum Zitat Braman SS. Chronic cough due to chronic bronchitis: ACCP evidence-based clinical practice guidelines. Chest. 2006;129(1 Suppl)104S–15S.PubMedCrossRef Braman SS. Chronic cough due to chronic bronchitis: ACCP evidence-based clinical practice guidelines. Chest. 2006;129(1 Suppl)104S–15S.PubMedCrossRef
30.
Zurück zum Zitat Kirwan JR, Chaput de Saintonge DM, Joyce CRB, Holmes J, Currey HLF. Inability of rheumatologists to describe their true policies for assessing rheumatoid arthritis. Ann Rheum Dis. 1986;45:156–61.PubMedCrossRef Kirwan JR, Chaput de Saintonge DM, Joyce CRB, Holmes J, Currey HLF. Inability of rheumatologists to describe their true policies for assessing rheumatoid arthritis. Ann Rheum Dis. 1986;45:156–61.PubMedCrossRef
31.
Zurück zum Zitat Bradley CP. Uncomfortable prescribing decisions: a critical incident study. BMJ. 1992;304(6822)294–6. PMID: 1739831, Feb 1.PubMedCrossRef Bradley CP. Uncomfortable prescribing decisions: a critical incident study. BMJ. 1992;304(6822)294–6. PMID: 1739831, Feb 1.PubMedCrossRef
Metadaten
Titel
How Do Community Practitioners Decide Whether to Prescribe Antibiotics for Acute Respiratory Tract Infections?
verfasst von
Robert S. Wigton, MD, MS
Carol A. Darr, PhD
Kitty K. Corbett, PhD, MPH
Devin R. Nickol, MD
Ralph Gonzales, MD, MSPH
Publikationsdatum
01.10.2008
Verlag
Springer-Verlag
Erschienen in
Journal of General Internal Medicine / Ausgabe 10/2008
Print ISSN: 0884-8734
Elektronische ISSN: 1525-1497
DOI
https://doi.org/10.1007/s11606-008-0707-9

Weitere Artikel der Ausgabe 10/2008

Journal of General Internal Medicine 10/2008 Zur Ausgabe

Leitlinien kompakt für die Innere Medizin

Mit medbee Pocketcards sicher entscheiden.

Seit 2022 gehört die medbee GmbH zum Springer Medizin Verlag

Update Innere Medizin

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.