Erschienen in:
01.03.2020 | Invited Commentary
Hyaluronate Carboxymethylcellulose-Based Bioresorbable Membrane Facilitates a Two-Stage Pancreaticoduodenectomy: Unnecessarily Necessary?
verfasst von:
Sudip Sanyal, Dileep N. Lobo
Erschienen in:
World Journal of Surgery
|
Ausgabe 3/2020
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Excerpt
Yamazaki et al. [
1] have presented an interesting retrospective cohort study on the safety and feasibility of the use of a hyaluronate carboxymethylcellulose (HCM)-based bioresorbable membrane to reduce adhesions at the second stage of a two-stage pancreaticoduodenectomy performed 4–8 weeks after the initial resection. The authors have reported reduced adhesions, thereby facilitating the second-stage reconstruction. There was also formation of good granulation tissue around the exteriorised pancreatic fistula despite the presence of the HCM-based membrane. The authors used operative duration and blood loss at the second stage as markers for the efficacy of the HCM-based membrane, but found no difference between the HCM-based membrane group (
n = 61) and the historical control group in which the HCM-based membrane was not used (
n = 145) in the rate of pancreatic fistula formation. …
