Erschienen in:
01.06.2005 | Poster Presentation
Hypermethylation of cyclin D2 and DAP kinase is associated with the lobular subtype of breast cancer
verfasst von:
U Lehmann, P Ahrens, LU Wingen, B Schlegelberger, F Länger, H Kreipe
Erschienen in:
Breast Cancer Research
|
Sonderheft 2/2005
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Excerpt
Promoter hypermethylation is a common inactivation mechanism in the development and progression of neoplastic transformation. For mammary carcinoma numerous genes have been described to be silenced due to aberrant methylation, some of them already in intraductal carcinomas. Much less is known about the association of hypermethylation events with the different histological subtypes of breast cancer. …