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Erschienen in: Clinical Rheumatology 8/2019

28.03.2019 | Original Article

Hypertension is associated with increased age at the onset of psoriasis and a higher body mass index in psoriatic disease

verfasst von: Rubén Queiro, Andrés Lorenzo, Patricia Tejón, Estefanía Pardo, Pablo Coto

Erschienen in: Clinical Rheumatology | Ausgabe 8/2019

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Abstract

Background and aims

High blood pressure (HBP) is a common comorbidity in psoriatic disease. Some studies indicate a higher prevalence of HBP among arthritis patients, in relation to psoriasis alone, within the psoriatic spectrum. Our objective was to study the prevalence of HBP in both types of patients as well as to analyse the factors associated with it.

Methods

A cross-sectional observational study of 600 patients with psoriatic disease attended in a multidisciplinary clinic of a reference centre. We first analysed the frequency of this comorbidity and then the factors associated with it using conditional logistic regression. The significant factors in this first model were introduced in a multivariate model using a backward step approach.

Results

A total of 144 patients were hypertensive (24%). Of patients with arthritis, 86/290 (29.7%) had HBP, compared with 58/310 (18.7%) with psoriasis (OR 1.7 95%, CI 1.25–2.50, p = 0.003). Hypertension was independently associated with higher age at onset of psoriasis (OR 1.04, 95%CI 1.03–1.06, p < 0.001) and a higher body mass index (OR 1.13, 95%CI, 1.06–1.22, p < 0.001).

Conclusions

HBP is more prevalent in patients with arthritis within the spectrum of psoriatic disease. Patients with a higher body mass index and those with later-onset psoriasis are more prone to this comorbidity.

Key Points

• The factors of psoriatic disease associated with HBP are little known.
• HBP is more prevalent in patients with arthritis within the spectrum of psoriatic disease.
• In patients with psoriatic disease, for each point of increase in the body mass index, the risk of HBP increases by 13%.
• For each year of onset of psoriasis above 40 years, the risk of HBP increases by 4%.
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Metadaten
Titel
Hypertension is associated with increased age at the onset of psoriasis and a higher body mass index in psoriatic disease
verfasst von
Rubén Queiro
Andrés Lorenzo
Patricia Tejón
Estefanía Pardo
Pablo Coto
Publikationsdatum
28.03.2019
Verlag
Springer London
Erschienen in
Clinical Rheumatology / Ausgabe 8/2019
Print ISSN: 0770-3198
Elektronische ISSN: 1434-9949
DOI
https://doi.org/10.1007/s10067-019-04519-z

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