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Current Sexual Health Reports

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26.11.2021 | Male Sexual Dysfunction and Disorders (N Thirumavalavan, Section Editor)

Hypogonadism Following Sperm Extraction: a Scoping Review of the Current Literature

verfasst von: Carlos Munoz-Lopez, Scott D. Lundy, Sarah C. Vij

Erschienen in: Current Sexual Health Reports | Ausgabe 4/2021

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Abstract

Purpose of Review

Hypogonadism following sperm retrieval (SR) is a potential consequence of surgery and may result in significant medical burden in a young patient population. There is a paucity of peer-reviewed evidence to guide clinicians and patients on the risk of hypogonadism following SR. Here, we conduct a review to describe the current literature concerning hypogonadism after SR.

Recent Findings

Fifteen citations in four categories of peer-reviewed literature were identified: surgical technique, literature review, original basic science, and original clinical science.

Summary

For men undergoing TESE and microTESE, there is an initial reduction in serum testosterone following surgery, but this typically recovers by 12 months post-operatively. Hypogonadism following SR is seen most often in patients with Klinefelter’s syndrome (KS), although current studies are underpowered and subject to selection bias. Research is needed to better characterize the clinical burden of hypogonadism following surgery and reflect the clinical diversity among KS patients.

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Titel: Hypogonadism Following Sperm Extraction: a Scoping Review of the Current Literature
verfasst von: Carlos Munoz-Lopez
Scott D. Lundy
Sarah C. Vij
Publikationsdatum: 26.11.2021
Verlag: Springer US
Erschienen in: Current Sexual Health Reports / Ausgabe 4/2021
Print ISSN: 1548-3584
Elektronische ISSN: 1548-3592
DOI: https://doi.org/10.1007/s11930-021-00320-9

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Hypogonadism Following Sperm Extraction: a Scoping Review of the Current Literature