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Erschienen in:

29.07.2022 | Hypoxämie | CME

Sauerstoff in der Akuttherapie

verfasst von: Prof. Dr. med. Jens Gottlieb

Erschienen in: Zeitschrift für Pneumologie | Ausgabe 6/2022

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Zusammenfassung

Sauerstoff (O2) ist ein Arzneimittel und soll in der Akuttherapie bei Vorliegen einer Hypoxämie ärztlich verordnet und dokumentiert, regelmäßig überwacht und reevaluiert werden. Zur Überwachung dient in der Akutmedizin die Pulsoxymetrie, bei Risikopatienten sind arterielle Blutgase zu bestimmen. Sowohl eine Hypoxämie als auch eine Hyperoxämie sind bei akut Kranken zu vermeiden. Es sollten Zielbereiche der O2-Sättigung (SpO2 [pulsoxymetrisch gemessene O2-Sättigung]) festgelegt werden. Diese hängen vom Hyperkapnierisiko und vom Beatmungsstatus ab: spontan atmende Patienten ohne bzw. mit Hyperkapnierisiko: Ziel‑SpO2 = 92–96 % bzw. 88–92 %, beatmete Patienten: arterielle O2-Sättigung zwischen 92 und 96 %. Die Zielbereiche gelten bis auf wenige Ausnahmen für alle Erwachsenen unabhängig von der Diagnose. Die O2-Applikationssysteme werden nach Patientensicherheit und -komfort ausgewählt. Bei Beendigung der O2-Gabe kann es bei vulnerablen Menschen zur Reboundhypoxämie kommen.
Literatur
2.
Zurück zum Zitat Kelly AM, McAlpine R, Kyle E (2001) How accurate are pulse oximeters in patients with acute exacerbations of chronic obstructive airways disease? Respir Med 95(5):336–340PubMedCrossRef Kelly AM, McAlpine R, Kyle E (2001) How accurate are pulse oximeters in patients with acute exacerbations of chronic obstructive airways disease? Respir Med 95(5):336–340PubMedCrossRef
3.
Zurück zum Zitat Ebmeier SJ, Barker M, Bacon M, Beasley RC, Bellomo R, Knee Chong C et al (2018) A two centre observational study of simultaneous pulse oximetry and arterial oxygen saturation recordings in intensive care unit patients. Anaesth Intensive Care 46(3):297–303PubMedCrossRef Ebmeier SJ, Barker M, Bacon M, Beasley RC, Bellomo R, Knee Chong C et al (2018) A two centre observational study of simultaneous pulse oximetry and arterial oxygen saturation recordings in intensive care unit patients. Anaesth Intensive Care 46(3):297–303PubMedCrossRef
4.
Zurück zum Zitat Bleyer AJ, Vidya S, Russell GB, Jones CM, Sujata L, Daeihagh P et al (2011) Longitudinal analysis of one million vital signs in patients in an academic medical center. Resuscitation 82(11):1387–1392PubMedCrossRef Bleyer AJ, Vidya S, Russell GB, Jones CM, Sujata L, Daeihagh P et al (2011) Longitudinal analysis of one million vital signs in patients in an academic medical center. Resuscitation 82(11):1387–1392PubMedCrossRef
5.
6.
Zurück zum Zitat Hafner S, Beloncle F, Koch A, Radermacher P, Asfar P (2015) Hyperoxia in intensive care, emergency, and peri-operative medicine: Dr. Jekyll or Mr. Hyde? A 2015 update. Ann Intensive Care 5(1):42PubMedPubMedCentralCrossRef Hafner S, Beloncle F, Koch A, Radermacher P, Asfar P (2015) Hyperoxia in intensive care, emergency, and peri-operative medicine: Dr. Jekyll or Mr. Hyde? A 2015 update. Ann Intensive Care 5(1):42PubMedPubMedCentralCrossRef
7.
Zurück zum Zitat Chu DK, Kim LHY, Young PJ, Zamiri N, Almenawer SA, Jaeschke R et al (2018) Mortality and morbidity in acutely ill adults treated with liberal versus conservative oxygen therapy (IOTA): a systematic review and meta-analysis. Lancet 391(10131):1693–1705PubMedCrossRef Chu DK, Kim LHY, Young PJ, Zamiri N, Almenawer SA, Jaeschke R et al (2018) Mortality and morbidity in acutely ill adults treated with liberal versus conservative oxygen therapy (IOTA): a systematic review and meta-analysis. Lancet 391(10131):1693–1705PubMedCrossRef
8.
Zurück zum Zitat Edmark L, Kostova-Aherdan K, Enlund M, Hedenstierna G (2003) Optimal oxygen concentration during induction of general anesthesia. Anesthesiology 98(1):28–33PubMedCrossRef Edmark L, Kostova-Aherdan K, Enlund M, Hedenstierna G (2003) Optimal oxygen concentration during induction of general anesthesia. Anesthesiology 98(1):28–33PubMedCrossRef
9.
Zurück zum Zitat Sackner MA, Landa J, Hirsch J, Zapata A (1975) Pulmonary effects of oxygen breathing. A 6‑hour study in normal men. Ann Intern Med 82(1):40–43PubMedCrossRef Sackner MA, Landa J, Hirsch J, Zapata A (1975) Pulmonary effects of oxygen breathing. A 6‑hour study in normal men. Ann Intern Med 82(1):40–43PubMedCrossRef
10.
Zurück zum Zitat Downs JB, Smith RA (1999) Increased inspired oxygen concentration may delay diagnosis and treatment of significant deterioration in pulmonary function. Crit Care Med 27(12):2844–2846PubMedCrossRef Downs JB, Smith RA (1999) Increased inspired oxygen concentration may delay diagnosis and treatment of significant deterioration in pulmonary function. Crit Care Med 27(12):2844–2846PubMedCrossRef
11.
Zurück zum Zitat Beasley R, Aldington S, Robinson G (2007) Is it time to change the approach to oxygen therapy in the breathless patient? Thorax 62(10):840–841PubMedPubMedCentralCrossRef Beasley R, Aldington S, Robinson G (2007) Is it time to change the approach to oxygen therapy in the breathless patient? Thorax 62(10):840–841PubMedPubMedCentralCrossRef
12.
Zurück zum Zitat Austin MA, Wills KE, Blizzard L, Walters EH, Wood-Baker R (2010) Effect of high flow oxygen on mortality in chronic obstructive pulmonary disease patients in prehospital setting: randomised controlled trial. BMJ 341:c5462PubMedPubMedCentralCrossRef Austin MA, Wills KE, Blizzard L, Walters EH, Wood-Baker R (2010) Effect of high flow oxygen on mortality in chronic obstructive pulmonary disease patients in prehospital setting: randomised controlled trial. BMJ 341:c5462PubMedPubMedCentralCrossRef
14.
Zurück zum Zitat Askie LM, Darlow BA, Finer N, Schmidt B, Stenson B, Tarnow-Mordi W et al (2018) Association between oxygen saturation targeting and death or disability in extremely preterm infants in the neonatal oxygenation prospective meta-analysis collaboration. JAMA 319(21):2190–2201PubMedPubMedCentralCrossRef Askie LM, Darlow BA, Finer N, Schmidt B, Stenson B, Tarnow-Mordi W et al (2018) Association between oxygen saturation targeting and death or disability in extremely preterm infants in the neonatal oxygenation prospective meta-analysis collaboration. JAMA 319(21):2190–2201PubMedPubMedCentralCrossRef
15.
Zurück zum Zitat Maitland K, Kiguli S, Olupot-Olupot P, Hamaluba M, Thomas K, Alaroker F et al (2021) Randomised controlled trial of oxygen therapy and high-flow nasal therapy in African children with pneumonia. Intensive Care Med 47(5):566–576PubMedPubMedCentralCrossRef Maitland K, Kiguli S, Olupot-Olupot P, Hamaluba M, Thomas K, Alaroker F et al (2021) Randomised controlled trial of oxygen therapy and high-flow nasal therapy in African children with pneumonia. Intensive Care Med 47(5):566–576PubMedPubMedCentralCrossRef
16.
Zurück zum Zitat Wyss-Dunant E (1955) Acclimatization shock; studies in the Himalaya mountains. Minerva Med 46(21):675–685PubMed Wyss-Dunant E (1955) Acclimatization shock; studies in the Himalaya mountains. Minerva Med 46(21):675–685PubMed
17.
Zurück zum Zitat van der Post J, Noordzij LA, de Kam ML, Blauw GJ, Cohen AF, van Gerven JM (2002) Evaluation of tests of central nervous system performance after hypoxemia for a model for cognitive impairment. J Psychopharmacol 16(4):337–343PubMedCrossRef van der Post J, Noordzij LA, de Kam ML, Blauw GJ, Cohen AF, van Gerven JM (2002) Evaluation of tests of central nervous system performance after hypoxemia for a model for cognitive impairment. J Psychopharmacol 16(4):337–343PubMedCrossRef
18.
Zurück zum Zitat Neill WA (1969) Effects of arterial hypoxemia and hyperoxia on oxygen availability for myocardial metabolism. Patients with and without coronary heart disease. Am J Cardiol 24(2):166–171PubMedCrossRef Neill WA (1969) Effects of arterial hypoxemia and hyperoxia on oxygen availability for myocardial metabolism. Patients with and without coronary heart disease. Am J Cardiol 24(2):166–171PubMedCrossRef
20.
Zurück zum Zitat Uronis H, McCrory DC, Samsa G, Currow D, Abernethy A (2011) Symptomatic oxygen for non-hypoxaemic chronic obstructive pulmonary disease. Cochrane Database Syst Rev 6:CD6429 Uronis H, McCrory DC, Samsa G, Currow D, Abernethy A (2011) Symptomatic oxygen for non-hypoxaemic chronic obstructive pulmonary disease. Cochrane Database Syst Rev 6:CD6429
21.
Zurück zum Zitat Uronis HE, Currow DC, McCrory DC, Samsa GP, Abernethy AP (2008) Oxygen for relief of dyspnoea in mildly- or non-hypoxaemic patients with cancer: a systematic review and meta-analysis. Br J Cancer 98(2):294–299PubMedPubMedCentralCrossRef Uronis HE, Currow DC, McCrory DC, Samsa GP, Abernethy AP (2008) Oxygen for relief of dyspnoea in mildly- or non-hypoxaemic patients with cancer: a systematic review and meta-analysis. Br J Cancer 98(2):294–299PubMedPubMedCentralCrossRef
22.
Zurück zum Zitat Pedersen T, Nicholson A, Hovhannisyan K, Moller AM, Smith AF, Lewis SR (2014) Pulse oximetry for perioperative monitoring. Cochrane Database Syst Rev 3:CD2013 Pedersen T, Nicholson A, Hovhannisyan K, Moller AM, Smith AF, Lewis SR (2014) Pulse oximetry for perioperative monitoring. Cochrane Database Syst Rev 3:CD2013
23.
Zurück zum Zitat Zavorsky GS, Cao J, Mayo NE, Gabbay R, Murias JM (2007) Arterial versus capillary blood gases: a meta-analysis. Respir Physiol Neurobiol 155(3):268–279PubMedCrossRef Zavorsky GS, Cao J, Mayo NE, Gabbay R, Murias JM (2007) Arterial versus capillary blood gases: a meta-analysis. Respir Physiol Neurobiol 155(3):268–279PubMedCrossRef
24.
Zurück zum Zitat Magnet FS, Majorski DS, Callegari J, Schwarz SB, Schmoor C, Windisch W et al (2017) Capillary PO2 does not adequately reflect arterial PO2 in hypoxemic COPD patients. Int J Chron Obstruct Pulmon Dis 12:2647–2653PubMedPubMedCentralCrossRef Magnet FS, Majorski DS, Callegari J, Schwarz SB, Schmoor C, Windisch W et al (2017) Capillary PO2 does not adequately reflect arterial PO2 in hypoxemic COPD patients. Int J Chron Obstruct Pulmon Dis 12:2647–2653PubMedPubMedCentralCrossRef
25.
Zurück zum Zitat Ekkernkamp E, Welte L, Schmoor C, Huttmann SE, Dreher M, Windisch W et al (2015) Spot check analysis of gas exchange: invasive versus noninvasive methods. Respiration 89(4):294–303PubMedCrossRef Ekkernkamp E, Welte L, Schmoor C, Huttmann SE, Dreher M, Windisch W et al (2015) Spot check analysis of gas exchange: invasive versus noninvasive methods. Respiration 89(4):294–303PubMedCrossRef
26.
Zurück zum Zitat Lim BL, Kelly AM (2010) A meta-analysis on the utility of peripheral venous blood gas analyses in exacerbations of chronic obstructive pulmonary disease in the emergency department. Eur J Emerg Med 17(5):246–248PubMedCrossRef Lim BL, Kelly AM (2010) A meta-analysis on the utility of peripheral venous blood gas analyses in exacerbations of chronic obstructive pulmonary disease in the emergency department. Eur J Emerg Med 17(5):246–248PubMedCrossRef
27.
Zurück zum Zitat Byrne AL, Bennett M, Chatterji R, Symons R, Pace NL, Thomas PS (2014) Peripheral venous and arterial blood gas analysis in adults: are they comparable? A systematic review and meta-analysis. Respirology 19(2):168–175PubMedCrossRef Byrne AL, Bennett M, Chatterji R, Symons R, Pace NL, Thomas PS (2014) Peripheral venous and arterial blood gas analysis in adults: are they comparable? A systematic review and meta-analysis. Respirology 19(2):168–175PubMedCrossRef
28.
Zurück zum Zitat Bingheng LJC, Yu C, Yijuan Y (2019) Comparison of peripheral venous and arterial blood gas in patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD): a metaanalysis. Notfall Rettungsmed 22:620–627CrossRef Bingheng LJC, Yu C, Yijuan Y (2019) Comparison of peripheral venous and arterial blood gas in patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD): a metaanalysis. Notfall Rettungsmed 22:620–627CrossRef
29.
Zurück zum Zitat Bloom BM, Grundlingh J, Bestwick JP, Harris T (2014) The role of venous blood gas in the emergency department: a systematic review and meta-analysis. Eur J Emerg Med 21(2):81–88PubMedCrossRef Bloom BM, Grundlingh J, Bestwick JP, Harris T (2014) The role of venous blood gas in the emergency department: a systematic review and meta-analysis. Eur J Emerg Med 21(2):81–88PubMedCrossRef
31.
Zurück zum Zitat Costello RW, Liston R, McNicholas WT (1995) Compliance at night with low flow oxygen therapy: a comparison of nasal cannulae and Venturi face masks. Thorax 50(4):405–406PubMedPubMedCentralCrossRef Costello RW, Liston R, McNicholas WT (1995) Compliance at night with low flow oxygen therapy: a comparison of nasal cannulae and Venturi face masks. Thorax 50(4):405–406PubMedPubMedCentralCrossRef
32.
Zurück zum Zitat Nolan KM, Winyard JA, Goldhill DR (1993) Comparison of nasal cannulae with face mask for oxygen administration to postoperative patients. Br J Anaesth 70(4):440–442PubMedCrossRef Nolan KM, Winyard JA, Goldhill DR (1993) Comparison of nasal cannulae with face mask for oxygen administration to postoperative patients. Br J Anaesth 70(4):440–442PubMedCrossRef
33.
Zurück zum Zitat Eastwood GM, O’Connell B, Gardner A, Considine J (2008) Evaluation of nasopharyngeal oxygen, nasal prongs and facemask oxygen therapy devices in adult patients: a randomised crossover trial. Anaesth Intensive Care 36(5):691–694PubMedCrossRef Eastwood GM, O’Connell B, Gardner A, Considine J (2008) Evaluation of nasopharyngeal oxygen, nasal prongs and facemask oxygen therapy devices in adult patients: a randomised crossover trial. Anaesth Intensive Care 36(5):691–694PubMedCrossRef
34.
Zurück zum Zitat Stausholm K, Rosenberg-Adamsen S, Skriver M, Kehlet H, Rosenberg J (1995) Comparison of three devices for oxygen administration in the late postoperative period. Br J Anaesth 74(5):607–609PubMedCrossRef Stausholm K, Rosenberg-Adamsen S, Skriver M, Kehlet H, Rosenberg J (1995) Comparison of three devices for oxygen administration in the late postoperative period. Br J Anaesth 74(5):607–609PubMedCrossRef
35.
Zurück zum Zitat Ayhan H, Iyigun E, Tastan S, Orhan ME, Ozturk E (2009) Comparison of two different oxygen delivery methods in the early postoperative period: randomized trial. J Adv Nurs 65(6):1237–1247PubMedCrossRef Ayhan H, Iyigun E, Tastan S, Orhan ME, Ozturk E (2009) Comparison of two different oxygen delivery methods in the early postoperative period: randomized trial. J Adv Nurs 65(6):1237–1247PubMedCrossRef
36.
Zurück zum Zitat Siemieniuk RAC, Chu DK, Kim LH, Guell-Rous MR, Alhazzani W, Soccal PM et al (2018) Oxygen therapy for acutely ill medical patients: a clinical practice guideline. BMJ 363:k4169PubMedCrossRef Siemieniuk RAC, Chu DK, Kim LH, Guell-Rous MR, Alhazzani W, Soccal PM et al (2018) Oxygen therapy for acutely ill medical patients: a clinical practice guideline. BMJ 363:k4169PubMedCrossRef
37.
Zurück zum Zitat Kopsaftis Z, Carson-Chahhoud KV, Austin MA, Wood-Baker R (2020) Oxygen therapy in the pre-hospital setting for acute exacerbations of chronic obstructive pulmonary disease. Cochrane Database Syst Rev 1:CD5534PubMed Kopsaftis Z, Carson-Chahhoud KV, Austin MA, Wood-Baker R (2020) Oxygen therapy in the pre-hospital setting for acute exacerbations of chronic obstructive pulmonary disease. Cochrane Database Syst Rev 1:CD5534PubMed
39.
Zurück zum Zitat Girardis M, Busani S, Damiani E, Donati A, Rinaldi L, Marudi A et al (2016) Effect of conservative vs conventional oxygen therapy on mortality among patients in an intensive care unit: the oxygen-ICU randomized clinical trial. JAMA 316(15):1583–1589PubMedCrossRef Girardis M, Busani S, Damiani E, Donati A, Rinaldi L, Marudi A et al (2016) Effect of conservative vs conventional oxygen therapy on mortality among patients in an intensive care unit: the oxygen-ICU randomized clinical trial. JAMA 316(15):1583–1589PubMedCrossRef
40.
Zurück zum Zitat Panwar R, Hardie M, Bellomo R, Barrot L, Eastwood GM, Young PJ et al (2016) Conservative versus liberal oxygenation targets for mechanically ventilated patients. A pilot multicenter randomized controlled trial. Am J Respir Crit Care Med 193(1):43–51PubMedCrossRef Panwar R, Hardie M, Bellomo R, Barrot L, Eastwood GM, Young PJ et al (2016) Conservative versus liberal oxygenation targets for mechanically ventilated patients. A pilot multicenter randomized controlled trial. Am J Respir Crit Care Med 193(1):43–51PubMedCrossRef
41.
Zurück zum Zitat Asfar P, Schortgen F, Boisrame-Helms J, Charpentier J, Guerot E, Megarbane B et al (2017) Hyperoxia and hypertonic saline in patients with septic shock (HYPERS2S): a two-by-two factorial, multicentre, randomised, clinical trial. Lancet Respir Med 5(3):180–190PubMedCrossRef Asfar P, Schortgen F, Boisrame-Helms J, Charpentier J, Guerot E, Megarbane B et al (2017) Hyperoxia and hypertonic saline in patients with septic shock (HYPERS2S): a two-by-two factorial, multicentre, randomised, clinical trial. Lancet Respir Med 5(3):180–190PubMedCrossRef
42.
Zurück zum Zitat Barrot L, Asfar P, Mauny F, Winiszewski H, Montini F, Badie J et al (2020) Liberal or conservative oxygen therapy for acute respiratory distress syndrome. N Engl J Med 382(11):999–1008PubMedCrossRef Barrot L, Asfar P, Mauny F, Winiszewski H, Montini F, Badie J et al (2020) Liberal or conservative oxygen therapy for acute respiratory distress syndrome. N Engl J Med 382(11):999–1008PubMedCrossRef
43.
Zurück zum Zitat ICU-ROX Investigators and the Australian and New Zealand Intensive Care Society Clinical Trials Group, Mackle D, Bellomo R, Bailey M et al (2020) Conservative oxygen therapy during mechanical ventilation in the ICU. N Engl J Med 382(11):989–998CrossRef ICU-ROX Investigators and the Australian and New Zealand Intensive Care Society Clinical Trials Group, Mackle D, Bellomo R, Bailey M et al (2020) Conservative oxygen therapy during mechanical ventilation in the ICU. N Engl J Med 382(11):989–998CrossRef
44.
Zurück zum Zitat Barbateskovic M, Schjorring OL, Russo Krauss S, Jakobsen JC, Meyhoff CS, Dahl RM et al (2019) Higher versus lower fraction of inspired oxygen or targets of arterial oxygenation for adults admitted to the intensive care unit. Cochrane Database Syst Rev 2019(11):CD12631PubMedCentral Barbateskovic M, Schjorring OL, Russo Krauss S, Jakobsen JC, Meyhoff CS, Dahl RM et al (2019) Higher versus lower fraction of inspired oxygen or targets of arterial oxygenation for adults admitted to the intensive care unit. Cochrane Database Syst Rev 2019(11):CD12631PubMedCentral
45.
Zurück zum Zitat Young P, Mackle D, Bellomo R, Bailey M, Beasley R, Deane A et al (2020) Conservative oxygen therapy for mechanically ventilated adults with sepsis: a post hoc analysis of data from the intensive care unit randomized trial comparing two approaches to oxygen therapy (ICU-ROX). Intensive Care Med 46(1):17–26PubMedCrossRef Young P, Mackle D, Bellomo R, Bailey M, Beasley R, Deane A et al (2020) Conservative oxygen therapy for mechanically ventilated adults with sepsis: a post hoc analysis of data from the intensive care unit randomized trial comparing two approaches to oxygen therapy (ICU-ROX). Intensive Care Med 46(1):17–26PubMedCrossRef
46.
Zurück zum Zitat Berbenetz N, Wang Y, Brown J, Godfrey C, Ahmad M, Vital FM et al (2019) Non-invasive positive pressure ventilation (CPAP or bilevel NPPV) for cardiogenic pulmonary oedema. Cochrane Database Syst Rev 4:CD5351PubMed Berbenetz N, Wang Y, Brown J, Godfrey C, Ahmad M, Vital FM et al (2019) Non-invasive positive pressure ventilation (CPAP or bilevel NPPV) for cardiogenic pulmonary oedema. Cochrane Database Syst Rev 4:CD5351PubMed
47.
Zurück zum Zitat Osadnik CR, Tee VS, Carson-Chahhoud KV, Picot J, Wedzicha JA, Smith BJ (2017) Non-invasive ventilation for the management of acute hypercapnic respiratory failure due to exacerbation of chronic obstructive pulmonary disease. Cochrane Database Syst Rev 7:CD4104PubMed Osadnik CR, Tee VS, Carson-Chahhoud KV, Picot J, Wedzicha JA, Smith BJ (2017) Non-invasive ventilation for the management of acute hypercapnic respiratory failure due to exacerbation of chronic obstructive pulmonary disease. Cochrane Database Syst Rev 7:CD4104PubMed
48.
Zurück zum Zitat Cabello JB, Burls A, Emparanza JI, Bayliss SE, Quinn T (2016) Oxygen therapy for acute myocardial infarction. Cochrane Database Syst Rev 12:CD7160PubMed Cabello JB, Burls A, Emparanza JI, Bayliss SE, Quinn T (2016) Oxygen therapy for acute myocardial infarction. Cochrane Database Syst Rev 12:CD7160PubMed
49.
Zurück zum Zitat Burls A, Emparanza JI, Quinn T, Cabello JB (2010) Oxygen use in acute myocardial infarction: an online survey of health professionals’ practice and beliefs. Emerg Med J 27(4):283–286PubMedCrossRef Burls A, Emparanza JI, Quinn T, Cabello JB (2010) Oxygen use in acute myocardial infarction: an online survey of health professionals’ practice and beliefs. Emerg Med J 27(4):283–286PubMedCrossRef
50.
Zurück zum Zitat Holmberg MJ, Nicholson T, Nolan JP, Schexnayder S, Reynolds J, Nation K et al (2020) Oxygenation and ventilation targets after cardiac arrest: a systematic review and meta-analysis. Resuscitation 152:107–115PubMedCrossRef Holmberg MJ, Nicholson T, Nolan JP, Schexnayder S, Reynolds J, Nation K et al (2020) Oxygenation and ventilation targets after cardiac arrest: a systematic review and meta-analysis. Resuscitation 152:107–115PubMedCrossRef
51.
Zurück zum Zitat Wang CH, Chang WT, Huang CH, Tsai MS, Yu PH, Wang AY et al (2014) The effect of hyperoxia on survival following adult cardiac arrest: a systematic review and meta-analysis of observational studies. Resuscitation 85(9):1142–1148PubMedCrossRef Wang CH, Chang WT, Huang CH, Tsai MS, Yu PH, Wang AY et al (2014) The effect of hyperoxia on survival following adult cardiac arrest: a systematic review and meta-analysis of observational studies. Resuscitation 85(9):1142–1148PubMedCrossRef
52.
Zurück zum Zitat Alhazzani W, Moller MH, Arabi YM, Loeb M, Gong MN, Fan E et al (2020) Surviving sepsis campaign: guidelines on the management of critically ill adults with coronavirus disease 2019 (COVID-19). Intensive Care Med 46(5):854–887PubMedPubMedCentralCrossRef Alhazzani W, Moller MH, Arabi YM, Loeb M, Gong MN, Fan E et al (2020) Surviving sepsis campaign: guidelines on the management of critically ill adults with coronavirus disease 2019 (COVID-19). Intensive Care Med 46(5):854–887PubMedPubMedCentralCrossRef
53.
Zurück zum Zitat Cohen AS, Burns B, Goadsby PJ (2009) High-flow oxygen for treatment of cluster headache: a randomized trial. JAMA 302(22):2451–2457PubMedCrossRef Cohen AS, Burns B, Goadsby PJ (2009) High-flow oxygen for treatment of cluster headache: a randomized trial. JAMA 302(22):2451–2457PubMedCrossRef
54.
Zurück zum Zitat Bennett MH, French C, Schnabel A, Wasiak J, Kranke P, Weibel S (2015) Normobaric and hyperbaric oxygen therapy for the treatment and prevention of migraine and cluster headache. Cochrane Database Syst Rev 12:CD5219 Bennett MH, French C, Schnabel A, Wasiak J, Kranke P, Weibel S (2015) Normobaric and hyperbaric oxygen therapy for the treatment and prevention of migraine and cluster headache. Cochrane Database Syst Rev 12:CD5219
55.
Zurück zum Zitat Lewis SR, Baker PE, Parker R, Smith AF (2021) High-flow nasal cannulae for respiratory support in adult intensive care patients. Cochrane Database Syst Rev 3:CD10172PubMed Lewis SR, Baker PE, Parker R, Smith AF (2021) High-flow nasal cannulae for respiratory support in adult intensive care patients. Cochrane Database Syst Rev 3:CD10172PubMed
56.
Zurück zum Zitat Wen Z, Wang W, Zhang H, Wu C, Ding J, Shen M (2017) Is humidified better than non-humidified low-flow oxygen therapy? A systematic review and meta-analysis. J Adv Nurs 73(11):2522–2533PubMedCrossRef Wen Z, Wang W, Zhang H, Wu C, Ding J, Shen M (2017) Is humidified better than non-humidified low-flow oxygen therapy? A systematic review and meta-analysis. J Adv Nurs 73(11):2522–2533PubMedCrossRef
57.
Zurück zum Zitat Poiroux L, Piquilloud L, Seegers V, Le Roy C, Colonval K, Agasse C et al (2018) Effect on comfort of administering bubble-humidified or dry oxygen: the oxyrea non-inferiority randomized study. Ann Intensive Care 8(1):126PubMedPubMedCentralCrossRef Poiroux L, Piquilloud L, Seegers V, Le Roy C, Colonval K, Agasse C et al (2018) Effect on comfort of administering bubble-humidified or dry oxygen: the oxyrea non-inferiority randomized study. Ann Intensive Care 8(1):126PubMedPubMedCentralCrossRef
Metadaten
Titel
Sauerstoff in der Akuttherapie
verfasst von
Prof. Dr. med. Jens Gottlieb
Publikationsdatum
29.07.2022
Verlag
Springer Medizin
Erschienen in
Zeitschrift für Pneumologie / Ausgabe 6/2022
Print ISSN: 2731-7404
Elektronische ISSN: 2731-7412
DOI
https://doi.org/10.1007/s10405-022-00453-1

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