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Erschienen in: Clinical Research in Cardiology 12/2018

24.05.2018 | Original Paper

ICD lead type and RV lead position in CRT-D recipients

verfasst von: Alexander P. Benz, Mate Vamos, Julia W. Erath, Peter Bogyi, Gabor Z. Duray, Stefan H. Hohnloser

Erschienen in: Clinical Research in Cardiology | Ausgabe 12/2018

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Abstract

Background

Data on preferred ICD lead type and optimal RV lead position in patients undergoing CRT-D implantation are limited.

Objectives

To compare dual- versus single-coil ICD leads and non-apical versus apical RV lead position and their impact on clinical parameters and survival in CRT-D recipients.

Methods

A total of 563 consecutive patients with advanced heart failure and indication for CRT-D implantation were enrolled in two European tertiary centers. Endpoints were improvement in NYHA functional class, changes in echo- and electrocardiographic parameters, and all-cause and cardiovascular mortality.

Results

In this retrospective analysis, a total of 313 (56%) dual- and 250 (44%) single-coil ICD leads were used. RV leads were placed non-apically in 262 (47%) and apically in 296 (53%) patients, respectively. Over a mean follow-up of 41 ± 34 months, all-cause mortality and cardiovascular mortality were similar for patients with dual- versus single-coil ICD lead (adjusted HR 0.81, 95% CI 0.58–1.12 and aHR 1.22, 95% CI 0.73–2.04) and non-apical versus apical RV lead position (aHR 0.98, 95% CI 0.71–1.36 and aHR 0.76, 95% CI 0.44–1.31). Non-apical RV lead position was associated with greater reduction in QRS duration after CRT implantation (− 14.4 ± 32.1 vs. − 4.3 ± 34.3 ms, p < 0.001).

Conclusions

We found no association between ICD lead type or RV lead position and outcomes in CRT-D recipients. Non-apical RV lead position was associated with larger reduction in QRS duration.
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Literatur
7.
Zurück zum Zitat Gold MR, Daubert J-C, Abraham WT et al (2013) Implantable defibrillators improve survival in patients with mildly symptomatic heart failure receiving cardiac resynchronization therapy: analysis of the long-term follow-up of remodeling in systolic left ventricular dysfunction (REVERSE). Circulation 6:1163–1168. https://doi.org/10.1161/CIRCEP.113.000570 CrossRefPubMed Gold MR, Daubert J-C, Abraham WT et al (2013) Implantable defibrillators improve survival in patients with mildly symptomatic heart failure receiving cardiac resynchronization therapy: analysis of the long-term follow-up of remodeling in systolic left ventricular dysfunction (REVERSE). Circulation 6:1163–1168. https://​doi.​org/​10.​1161/​CIRCEP.​113.​000570 CrossRefPubMed
11.
18.
Zurück zum Zitat Gold MR, Olsovsky MR, Pelini MA, Peters RW, Shorofsky SR (1998) Comparison of single- and dual-coil active pectoral defibrillation lead systems. J Am Coll Cardiol 31(6):1391–1394CrossRef Gold MR, Olsovsky MR, Pelini MA, Peters RW, Shorofsky SR (1998) Comparison of single- and dual-coil active pectoral defibrillation lead systems. J Am Coll Cardiol 31(6):1391–1394CrossRef
22.
Zurück zum Zitat Wilkoff BL, Cook JR, Epstein AE et al (2002) Dual-chamber pacing or ventricular backup pacing in patients with an implantable defibrillator: the Dual Chamber and VVI Implantable Defibrillator (DAVID) Trial. JAMA 288(24):3115–3123CrossRef Wilkoff BL, Cook JR, Epstein AE et al (2002) Dual-chamber pacing or ventricular backup pacing in patients with an implantable defibrillator: the Dual Chamber and VVI Implantable Defibrillator (DAVID) Trial. JAMA 288(24):3115–3123CrossRef
Metadaten
Titel
ICD lead type and RV lead position in CRT-D recipients
verfasst von
Alexander P. Benz
Mate Vamos
Julia W. Erath
Peter Bogyi
Gabor Z. Duray
Stefan H. Hohnloser
Publikationsdatum
24.05.2018
Verlag
Springer Berlin Heidelberg
Erschienen in
Clinical Research in Cardiology / Ausgabe 12/2018
Print ISSN: 1861-0684
Elektronische ISSN: 1861-0692
DOI
https://doi.org/10.1007/s00392-018-1286-3

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