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14.08.2018 | Invited Review

ICUD-SIU International Consultation on Bladder Cancer 2017: management of non-muscle invasive bladder cancer

verfasst von: Leonardo L. Monteiro, J. Alfred Witjes, Piyush K. Agarwal, Christopher B. Anderson, Trinity J. Bivalacqua, Bernard H. Bochner, Joost L. Boormans, Sam S. Chang, Jose L. Domínguez-Escrig, James M. McKiernan, Colin Dinney, Guilherme Godoy, Girish S. Kulkarni, Paramananthan Mariappan, Michael A. O’Donnell, Cyrill A. Rentsch, Jay B. Shah, Eduardo Solsona, Robert S. Svatek, Antoine G. van der Heijden, F. Johannes P. van Valenberg, Wassim Kassouf

Erschienen in: World Journal of Urology | Ausgabe 1/2019

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Abstract

Purpose

To provide a summary of the Third International Consultation on Bladder Cancer recommendations for the management of non-muscle invasive bladder cancer (NMIBC).

Methods

A detailed review of the literature was performed focusing on original articles for the management of NMIBC. An international committee assessed and graded the articles based on the Oxford Centre for Evidence-based Medicine system. The entire spectrum of NMIBC was covered such as prognostic factors of recurrence and progression, risk stratification, staging, management of positive urine cytology with negative white light cystoscopy, indications of bladder and prostatic urethral biopsies, management of Ta low grade (LG) and high risk tumors (Ta high grade [HG], T1, carcinoma in situ [CIS]), impact of BCG strain and host on outcomes, management of complications of intravesical therapy, role of alternative therapies, indications for early cystectomy, surveillance strategies, and new treatments. The working group provides several recommendations on the management of NMIBC.

Results

Recommendations were summarized with regard to staging; management of primary and recurrent LG Ta and high risk disease, positive urine cytology with negative white light cystoscopy and prostatic urethral involvement; indications for timely cystectomy; and surveillance strategies.

Conclusion

NMIBC remains a common and challenging malignancy to manage. Accurate staging, grading, and risk stratification are critical determinants of the management and outcomes of these patients. Current tools for risk stratification are limited but informative, and should be used in clinical practice when determining diagnosis, surveillance, and treatment of NMIBC.

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Titel: ICUD-SIU International Consultation on Bladder Cancer 2017: management of non-muscle invasive bladder cancer
verfasst von: Leonardo L. Monteiro
J. Alfred Witjes
Piyush K. Agarwal
Christopher B. Anderson
Trinity J. Bivalacqua
Bernard H. Bochner
Joost L. Boormans
Sam S. Chang
Jose L. Domínguez-Escrig
James M. McKiernan
Colin Dinney
Guilherme Godoy
Girish S. Kulkarni
Paramananthan Mariappan
Michael A. O’Donnell
Cyrill A. Rentsch
Jay B. Shah
Eduardo Solsona
Robert S. Svatek
Antoine G. van der Heijden
F. Johannes P. van Valenberg
Wassim Kassouf
Publikationsdatum: 14.08.2018
Verlag: Springer Berlin Heidelberg
Erschienen in: World Journal of Urology / Ausgabe 1/2019
Print ISSN: 0724-4983
Elektronische ISSN: 1433-8726
DOI: https://doi.org/10.1007/s00345-018-2438-9

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ICUD-SIU International Consultation on Bladder Cancer 2017: management of non-muscle invasive bladder cancer

Abstract

Purpose

Methods

Results

Conclusion

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