Skip to main content
Erschienen in: European Spine Journal 6/2021

22.02.2021 | Original Article

Identifying factors influencing mortality in patients aged over 65 following an acute type II odontoid process fracture. A retrospective cohort study

verfasst von: Timothy Lukins, Lana Nguyen, Mitchell A. Hansen, Richard D. Ferch

Erschienen in: European Spine Journal | Ausgabe 6/2021

Einloggen, um Zugang zu erhalten

Abstract

Objective

Compare short-term mortality rates following operative and nonoperative management of geriatric patients following an acute type II odontoid process fracture.

Methods

One hundred forty-one patients with a type II odontoid fracture were identified from a single centre between 2002 and 2018. Patient demographics, details of injury and management, plus mortality data were collected. The incidence of mortality at 3 and 12 months was calculated, and a multivariate model built which included the treatment modality variable and allowed adjustment for six individual confounders.

Results

Of the 141 patients with a type II odontoid process fracture, 39 were managed operatively, while 102 were managed nonoperatively. Relative to the nonoperative group, the operative group was younger (79.0 ± 7.0 vs. 83.7 ± 7.6), more likely to have odontoid angulation > 15° (74.4% vs. 43.1%, p < 0.01), and a greater proportion having fracture displacement > 2 mm (74.4% vs. 31.4%, p < 0.01). Both groups were comparable for gender, comorbidities, and associated injuries. On univariate analysis of treatment modality, the odds ratio of 3-month mortality with nonoperative management was 2.55 (95% CI: 0.82–7.92; p = 0.08), whilst at 12-months it was 3.12 (95% CI: 1.11–8.69; p = 0.02). On multivariate analysis of 12-month mortality, however, treatment modality was not found to be significant. This multivariate analysis suggested that increasing age, male gender, and injury severity were significant predictors of 12-month mortality.

Conclusion

In contrast to the findings of a number of previous studies, operative management may not influence survival at 3- and 12-months.
Literatur
3.
Zurück zum Zitat Anderson LD, D’Alonzo RT (1974) Fractures of the odontoid process of the axis. J Bone Joint Surg Am 56(8):1663–1674CrossRef Anderson LD, D’Alonzo RT (1974) Fractures of the odontoid process of the axis. J Bone Joint Surg Am 56(8):1663–1674CrossRef
6.
Zurück zum Zitat Chiba K, Fujimura Y, Toyama Y, Fujii E, Nakanishi T, Hirabayashi K (1996) Treatment protocol for fractures of the odontoid process. J Spinal Disord 9(4):267–276CrossRef Chiba K, Fujimura Y, Toyama Y, Fujii E, Nakanishi T, Hirabayashi K (1996) Treatment protocol for fractures of the odontoid process. J Spinal Disord 9(4):267–276CrossRef
7.
Zurück zum Zitat Chapman J, Smith JS, Kopjar B, Vaccaro AR, Arnold P, Shaffrey CI, Fehlings MG (2013) The AOSpine North America geriatric odontoid fracture mortality study: a retrospective review of mortality outcomes for operative versus nonoperative treatment of 322 patients with long-term follow-up. Spine (Phila Pa 1976) 38(13):1098–1104. https://doi.org/10.1097/BRS.0b013e318286f0cfCrossRef Chapman J, Smith JS, Kopjar B, Vaccaro AR, Arnold P, Shaffrey CI, Fehlings MG (2013) The AOSpine North America geriatric odontoid fracture mortality study: a retrospective review of mortality outcomes for operative versus nonoperative treatment of 322 patients with long-term follow-up. Spine (Phila Pa 1976) 38(13):1098–1104. https://​doi.​org/​10.​1097/​BRS.​0b013e318286f0cf​CrossRef
13.
Zurück zum Zitat Smith JS, Kepler CK, Kopjar B, Harrop JS, Arnold P, Chapman JR, Fehlings MG, Vaccaro AR, Shaffrey CI (2013) Effect of type II odontoid fracture nonunion on outcome among elderly patients treated without surgery: based on the AOSpine North America geriatric odontoid fracture study. Spine (Phila Pa 1976) 38(26):2240–2246. https://doi.org/10.1097/BRS.0000000000000009CrossRef Smith JS, Kepler CK, Kopjar B, Harrop JS, Arnold P, Chapman JR, Fehlings MG, Vaccaro AR, Shaffrey CI (2013) Effect of type II odontoid fracture nonunion on outcome among elderly patients treated without surgery: based on the AOSpine North America geriatric odontoid fracture study. Spine (Phila Pa 1976) 38(26):2240–2246. https://​doi.​org/​10.​1097/​BRS.​0000000000000009​CrossRef
14.
Zurück zum Zitat Vaccaro AR, Kepler CK, Kopjar B, Chapman J, Shaffrey C, Arnold P, Gokaslan Z, Brodke D, France J, Dekutoski M, Sasso R, Yoon ST, Bono C, Harrop J, Fehlings MG (2013) Functional and quality-of-life outcomes in geriatric patients with type-II dens fracture. J Bone Joint Surg Am 95(8):729–735. https://doi.org/10.2106/JBJS.K.01636CrossRefPubMed Vaccaro AR, Kepler CK, Kopjar B, Chapman J, Shaffrey C, Arnold P, Gokaslan Z, Brodke D, France J, Dekutoski M, Sasso R, Yoon ST, Bono C, Harrop J, Fehlings MG (2013) Functional and quality-of-life outcomes in geriatric patients with type-II dens fracture. J Bone Joint Surg Am 95(8):729–735. https://​doi.​org/​10.​2106/​JBJS.​K.​01636CrossRefPubMed
16.
Zurück zum Zitat Baker S, O’Neill B, Haddon WJ, Long W (1974) The injury severity score: a method for describing patients with multiple injuries and evaluating emergency care. J Trauma Acute Care Surg 14(3):187–196CrossRef Baker S, O’Neill B, Haddon WJ, Long W (1974) The injury severity score: a method for describing patients with multiple injuries and evaluating emergency care. J Trauma Acute Care Surg 14(3):187–196CrossRef
19.
Zurück zum Zitat StataCorp, (2019) Stata Statistical Software, 16th edn. StataCorp LLC, College Station StataCorp, (2019) Stata Statistical Software, 16th edn. StataCorp LLC, College Station
21.
Zurück zum Zitat Smith HE, Kerr SM, Maltenfort M, Chaudhry S, Norton R, Albert TJ, Harrop J, Hilibrand AS, Anderson DG, Kopjar B, Brodke DS, Wang JC, Fehlings MG, Chapman JR, Patel A, Arnold PM, Vaccaro AR (2008) Early complications of surgical versus conservative treatment of isolated type II odontoid fractures in octogenarians: a retrospective cohort study. J Spinal Disord Tech 21(8):535–539. https://doi.org/10.1097/BSD.0b013e318163570bCrossRefPubMed Smith HE, Kerr SM, Maltenfort M, Chaudhry S, Norton R, Albert TJ, Harrop J, Hilibrand AS, Anderson DG, Kopjar B, Brodke DS, Wang JC, Fehlings MG, Chapman JR, Patel A, Arnold PM, Vaccaro AR (2008) Early complications of surgical versus conservative treatment of isolated type II odontoid fractures in octogenarians: a retrospective cohort study. J Spinal Disord Tech 21(8):535–539. https://​doi.​org/​10.​1097/​BSD.​0b013e318163570b​CrossRefPubMed
Metadaten
Titel
Identifying factors influencing mortality in patients aged over 65 following an acute type II odontoid process fracture. A retrospective cohort study
verfasst von
Timothy Lukins
Lana Nguyen
Mitchell A. Hansen
Richard D. Ferch
Publikationsdatum
22.02.2021
Verlag
Springer Berlin Heidelberg
Erschienen in
European Spine Journal / Ausgabe 6/2021
Print ISSN: 0940-6719
Elektronische ISSN: 1432-0932
DOI
https://doi.org/10.1007/s00586-020-06694-z

Weitere Artikel der Ausgabe 6/2021

European Spine Journal 6/2021 Zur Ausgabe

Arthropedia

Grundlagenwissen der Arthroskopie und Gelenkchirurgie. Erweitert durch Fallbeispiele, Videos und Abbildungen. 
» Jetzt entdecken

Update Orthopädie und Unfallchirurgie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.