Erschienen in:
24.09.2019 | Sarcoma
If Active Surveillance is the Standard of Care for Desmoid Patients, When Should Intervention be Considered?
verfasst von:
Rebecca A. Gladdy, MD, PhD, FRCSC, FACS, Abha A. Gupta, MD, MSc, FRCPC
Erschienen in:
Annals of Surgical Oncology
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Ausgabe 13/2019
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Excerpt
In this issue, experts at Royal Marsden Hospital report the outcomes for a large cohort of patients with desmoid tumor (DT) who did not undergo intervention at the time of their initial diagnosis.
1 In the management of DT patients, understanding in whom to intervene and when are seminal questions that are not yet resolved. What has been clarified in DT clinical care is that the need for upfront surgery has evolved, at most, to second-line consideration after a period of observation.
2 In this vein, the current report describes 584 DT patients during an 18-year period, 168 of whom were managed with active surveillance. Most of these patients did not need any form of additional treatment during the follow-up period. The main indications in those treated were tumor progression, pain, or both, which occurred within 2.5 years after diagnosis. …