Erschienen in:
01.11.2010 | Review
IgG4-Related Sclerosing Disease: A Novel Mimic of Inflammatory Bowel Disease
verfasst von:
Neeraj Narula, Monica Vasudev, John K. Marshall
Erschienen in:
Digestive Diseases and Sciences
|
Ausgabe 11/2010
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Abstract
High levels of IgG4-positive plasma cells are commonly seen in autoimmune pancreatitis. It has recently become evident that autoimmune pancreatitis is one component of a larger multi-system disease. IgG4-positive plasma cells have been identified in many extrapancreatic tissues, including the colon, biliary tract, liver, and lungs, and thus the term “IgG4-related sclerosing disease” has been proposed. Awareness of IgG4-related sclerosing disease is important, as it has been shown to mimic other conditions like malignancy. This review discusses IgG4-related colitis and its potential for mimicking inflammatory bowel disease.