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Current Cardiovascular Imaging Reports
Erschienen in: Current Cardiovascular Imaging Reports 1/2012

01.02.2012 | Cardiac Molecular Imaging (F Jaffer, Section Editor)

Imaging Cell Therapy for Myocardial Regeneration

verfasst von: Hualei Zhang, Hui Qiao, Victor A. Ferrari, Rong Zhou

Erschienen in: Current Cardiovascular Imaging Reports | Ausgabe 1/2012

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Abstract

Noninvasive or minimally invasive imaging techniques are essential for developing strategies and assessing outcomes of cell-based therapies for myocardial regeneration, also referred to as cellular cardiomyoplasty. Imaging-based monitoring of cell survival is useful for selection of optimal cell type and evaluating strategies to enhance engraftment. Imaging-derived surrogate end points including global and regional contractile function, myocardial blood flow, or perfusion and bioenergetics have been used in clinical trials or in relevant large animal models to evaluate the therapeutic effect and mechanisms of action of cellular cardiomyoplasty. New techniques are emerging to assess electrical integration of donor cells with host cardiomyocytes. This review will summarize and highlight important and informative findings revealed by imaging in clinical and preclinical cellular cardiomyoplasty studies over the past 3 years.
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Metadaten
Titel
Imaging Cell Therapy for Myocardial Regeneration
verfasst von
Hualei Zhang
Hui Qiao
Victor A. Ferrari
Rong Zhou
Publikationsdatum
01.02.2012
Verlag
Current Science Inc.
Erschienen in
Current Cardiovascular Imaging Reports / Ausgabe 1/2012
Print ISSN: 1941-9066
Elektronische ISSN: 1941-9074
DOI
https://doi.org/10.1007/s12410-011-9119-z

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