05.08.2023
Immediate Lymphatic Reconstruction in Breast Cancer Treatment: Clinical Trials and State of the Evidence
verfasst von:
Sergey G. Toshinskiy, Elizabeth A. Bailey, Graham S. Schwarz
Erschienen in:
Current Breast Cancer Reports
|
Ausgabe 3/2023
Einloggen, um Zugang zu erhalten
Abstract
Purpose of Review
Breast cancer-related lymphedema (BCRL) is a major contributor to morbidity in breast cancer survivors. Immediate lymphatic reconstruction (ILR) has emerged as a promising surgical option for prevention of BCRL. The purpose of this review is to critically evaluate recent literature on ILR in breast cancer patients.
Recent Findings
Short-term outcomes of ILR at most centers have shown low BCRL rates similar to those seen with sentinel lymph node biopsy. Some centers reporting more than 4-year follow-up have demonstrated up to 50–75% BCRL risk reduction following axillary lymph node dissection (ALND). Others have demonstrated equivocal results from ILR. ILR appears to be surgically and oncologically safe.
Summary
ILR continues to be a promising surgical technique to reduce the risk of BCRL following ALND. Ongoing evaluation is needed to characterize the extent of protective effect conferred by ILR.