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03.06.2020 | Research Article | Ausgabe 4/2020

International Journal of Clinical Pharmacy 4/2020

Impact of a pharmacist-administered deprescribing intervention on nursing home residents: a randomized controlled trial

Zeitschrift:
International Journal of Clinical Pharmacy > Ausgabe 4/2020
Autoren:
Cathy Balsom, Nicole Pittman, Renee King, Debbie Kelly
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Abstract

Background Polypharmacy is prevalent among long-term care residents in Canada, with 48.4% receiving ten or more different medications and 40.7% chronically prescribed potentially inappropriate medications. Objective We implemented a pharmacist-administered deprescribing program in a long-term care facility to determine if the number of medications taken per resident could be reduced. Setting: A long-term care facility in Newfoundland and Labrador, Canada from February 2017 to February 2018. Method: Residents were randomized to receive either a deprescribing-focused medication review by a pharmacist or usual care. Main outcome measure Change in the number of medications at 3 and 6 months. Results Forty-five residents enrolled in the study (n = 22 intervention, n = 23 control). Seventy-eight deprescribing recommendations were made, and 85.1% were successfully implemented. The average number of medications taken by residents in the intervention group was 2.68 less than the control group (p < 0.02; 95% CI − 4.284, − 1.071) at 3 months and 2.88 less (p = 0.02, 95% CI − 4.543, − 1.112) at 6 months. In 14.9% of cases, a medication had to be restarted after deprescribing was attempted because symptoms returned. Conclusion: A pharmacist-led deprescribing intervention can reduce the number of unnecessary and potentially harmful medications taken by LTC residents.

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