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Erschienen in: Graefe's Archive for Clinical and Experimental Ophthalmology 12/2016

24.08.2016 | Cataract

Impact of allergy and atopy on the risk of pseudophakic cystoid macular edema

verfasst von: Friederike Schaub, Werner Adler, Meike C. Koenig, Philip Enders, Rafael S. Grajewski, Claus Cursiefen, Ludwig M. Heindl

Erschienen in: Graefe's Archive for Clinical and Experimental Ophthalmology | Ausgabe 12/2016

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Abstract

Purpose

To assess the risk of pseudophakic cystoid macular edema (PCME) following cataract surgery in patients with allergies and/or atopic disorders.

Patients and methods

Medical records of 3,850 consecutive eyes that underwent cataract surgery were retrospectively reviewed for prevalence of allergies and atopic status and development of PCME. Patients with any known risk factors for PCME were excluded. Macular examination was performed using spectral-domain optical coherence tomography (SD-OCT) before and at 4, 8, 12, 16, 24, and 36 weeks after surgery. If both eyes in one patient underwent cataract surgery, one eye was randomly selected. Odds ratios and confidence intervals were estimated.

Results

Out of 240 patients enrolled in this series, 65 patients (27.1 %) showed positive allergic status, 19 patients (7.9 %) suffered from atopic syndromes, and 11 (4.6 %) showed both (allergies and atopic diseases). PCME occurred in eight patients (12.3 %) of the allergy cohort, whereas no patient (0 %) of the atopy cohort developed PCME. The risk of PCME was comparable in patients with allergies or atopic diseases to patients without allergies or atopy (allergy: p = 0.635; odds ratio (OR) 1.303, 95 % confidence interval (CI) 0.461–3.398; atopy: p = 0.234; OR 0.000, 95 % CI 0–1.815).

Conclusion

Positive status of allergy or atopy does not seem to increase the risk of PCME. Therefore, postoperative treatment after cataract surgery does not have to be modified in allergic or atopic patients.
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Metadaten
Titel
Impact of allergy and atopy on the risk of pseudophakic cystoid macular edema
verfasst von
Friederike Schaub
Werner Adler
Meike C. Koenig
Philip Enders
Rafael S. Grajewski
Claus Cursiefen
Ludwig M. Heindl
Publikationsdatum
24.08.2016
Verlag
Springer Berlin Heidelberg
Erschienen in
Graefe's Archive for Clinical and Experimental Ophthalmology / Ausgabe 12/2016
Print ISSN: 0721-832X
Elektronische ISSN: 1435-702X
DOI
https://doi.org/10.1007/s00417-016-3474-z

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