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Erschienen in: Pediatric Cardiology 8/2019

24.08.2019 | Original Article

Impact of Ethnicity on the Prevalence of Early Repolarization Pattern in Children: Comparison Between Caucasian and African Populations

verfasst von: Antonio Creta, Michele Arigliani, Giuseppe di Gioia, Roberta Lapenna, Fabio Quintarelli, Mario Fittipaldi, Vincenzo Antinolfi, Ranieri Bettini, Davide Costanzo, Alessandro Cruciani, Stefano Di Berardino, Riccardo Giorgino, Umberto Satriano, Giuseppe Mangiameli, Dario Sut, Marco Caricato, Paola Cogo, Alessandro Proclemer, Giovanni Mottini, Pier D. Lambiase, Rui Providência

Erschienen in: Pediatric Cardiology | Ausgabe 8/2019

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Abstract

The patterns and prevalence of early repolarization pattern (ER) in pediatric populations from ethnic backgrounds other than Caucasian have not been determined. Black African children (ages 4–12) from north-west Madagascar were prospectively recruited and their ECGs compared with those of age- and sex-matched Caucasian ethnicity individuals. ER was defined by ≥ 0.1 mV J-point elevation in at least two contiguous inferior and/or lateral ECG leads. A total of 616 children were included. There was a trend toward a higher frequency of ER in the Africans compared to the Caucasians (23.3% vs. 17.1%, respectively, p = 0.053). The subtype (slurred vs. notched) and location of ER (lateral, inferior, or inferior-lateral) were significantly different in the two groups (p < 0.001 and p = 0.020, respectively). There was no significant difference in the number of high-risk ECG features of ERP (i.e., horizontal/descendent pattern, inferior or inferior-lateral location or J-waves ≥ 2 mm) between African and Caucasian children. On the multivariate analysis, African ethnicity was an independent predictive factor of ER (OR 3.57, 95% CI 2.04–6.25, p < 0.001). African children have an increased risk of ER compared to Caucasian counterparts. Future studies should clarify the clinical and prognostic significance of ER in the pediatric population, and whether ethnicity has an impact on the outcomes.
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Metadaten
Titel
Impact of Ethnicity on the Prevalence of Early Repolarization Pattern in Children: Comparison Between Caucasian and African Populations
verfasst von
Antonio Creta
Michele Arigliani
Giuseppe di Gioia
Roberta Lapenna
Fabio Quintarelli
Mario Fittipaldi
Vincenzo Antinolfi
Ranieri Bettini
Davide Costanzo
Alessandro Cruciani
Stefano Di Berardino
Riccardo Giorgino
Umberto Satriano
Giuseppe Mangiameli
Dario Sut
Marco Caricato
Paola Cogo
Alessandro Proclemer
Giovanni Mottini
Pier D. Lambiase
Rui Providência
Publikationsdatum
24.08.2019
Verlag
Springer US
Erschienen in
Pediatric Cardiology / Ausgabe 8/2019
Print ISSN: 0172-0643
Elektronische ISSN: 1432-1971
DOI
https://doi.org/10.1007/s00246-019-02185-1

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