Skip to main content
Erschienen in: Pediatric Cardiology 2/2016

01.02.2016 | Review Article

Impact of Exercise Training in Aerobic Capacity and Pulmonary Function in Children and Adolescents After Congenital Heart Disease Surgery: A Systematic Review with Meta-analysis

verfasst von: Mansueto Gomes-Neto, Micheli Bernardone Saquetto, Cassio Magalhães da Silva e Silva, Cristiano Sena Conceição, Vitor Oliveira Carvalho

Erschienen in: Pediatric Cardiology | Ausgabe 2/2016

Einloggen, um Zugang zu erhalten

Abstract

The aim of the study was to examine the effects of exercise training on aerobic capacity and pulmonary function in children and adolescents after congenital heart disease surgery. We searched MEDLINE, Cochrane Controlled Trials Register, EMBASE, (from the earliest date available to January 2015) for controlled trials that evaluated the effects of exercise training on aerobic capacity and pulmonary function (forced expiratory volume in 1 s and forced vital capacity) in children and adolescents after congenital heart disease surgery. Weighted mean differences and 95 % confidence intervals (CIs) were calculated,, and heterogeneity was assessed using the I 2 test. Eight trials (n = 292) met the study criteria. The results suggested that exercise training compared with control had a positive impact on peak VO2. Exercise training resulted in improvement in peak VO2 weighted mean difference (3.68 mL kg−1 min−1, 95 % CI 1.58–5.78). The improvement in forced expiratory volume in 1 s and forced vital capacity after exercise training was not significant. Exercise training may improve peak VO2 in children and adolescents after congenital heart disease surgery and should be considered for inclusion in cardiac rehabilitation. Further larger randomized controlled trials are urgently needed to investigate different types of exercise and its effects on the quality of life.
Literatur
1.
Zurück zum Zitat Achttien RJ, Staal JB, van der Voort S, Kemps HM, Koers H, Jongert MW et al (2013) Exercise-based cardiac rehabilitation in patients with coronary heart disease: a practice guideline. Neth Heart J 21:429–438PubMedCentralCrossRefPubMed Achttien RJ, Staal JB, van der Voort S, Kemps HM, Koers H, Jongert MW et al (2013) Exercise-based cardiac rehabilitation in patients with coronary heart disease: a practice guideline. Neth Heart J 21:429–438PubMedCentralCrossRefPubMed
2.
Zurück zum Zitat Amiard V, Jullien H, Nassif D, Bach V, Maingourd Y, Ahmaidi S (2008) Effects of home-based training at dyspnea threshold in children surgically repaired for congenital heart disease. Congenit Heart Dis 3:191–199CrossRefPubMed Amiard V, Jullien H, Nassif D, Bach V, Maingourd Y, Ahmaidi S (2008) Effects of home-based training at dyspnea threshold in children surgically repaired for congenital heart disease. Congenit Heart Dis 3:191–199CrossRefPubMed
3.
Zurück zum Zitat Brassard P, Bédard E, Jobin J, Rodés-Cabau J, Poirier P (2006) Exercise capacity and impact of exercise training in patients after a Fontan procedure: a review. Can J Cardiol 22(6):489–495PubMedCentralCrossRefPubMed Brassard P, Bédard E, Jobin J, Rodés-Cabau J, Poirier P (2006) Exercise capacity and impact of exercise training in patients after a Fontan procedure: a review. Can J Cardiol 22(6):489–495PubMedCentralCrossRefPubMed
4.
Zurück zum Zitat Brassard P, Bédard E, Jobin J, Rodés-Cabau J, Poirier P (2006) Exercise capacity and impact of exercise training in patients after a Fontan procedure: a review. Can J Cardiol 6(1):489–495CrossRef Brassard P, Bédard E, Jobin J, Rodés-Cabau J, Poirier P (2006) Exercise capacity and impact of exercise training in patients after a Fontan procedure: a review. Can J Cardiol 6(1):489–495CrossRef
5.
Zurück zum Zitat Canobbio MM (2001) Health care issues facing adolescents with congenital heart disease. J Pediatr Nurs 16:363–370CrossRefPubMed Canobbio MM (2001) Health care issues facing adolescents with congenital heart disease. J Pediatr Nurs 16:363–370CrossRefPubMed
7.
Zurück zum Zitat Cooper DS, Jacobs JP, Chai PJ et al (2008) Pulmonary complications associated with the treatment of patients with congenital cardiac disease: consensus definitions from the multi-societal database committee for pediatric and congenital heart disease. Cardiol Young 18(Suppl 2):215–221CrossRefPubMed Cooper DS, Jacobs JP, Chai PJ et al (2008) Pulmonary complications associated with the treatment of patients with congenital cardiac disease: consensus definitions from the multi-societal database committee for pediatric and congenital heart disease. Cardiol Young 18(Suppl 2):215–221CrossRefPubMed
8.
Zurück zum Zitat Dickstein K, Cohen-Solal A, Filippatos G, McMurray JJ, Ponikowski P, Poole-Wilson PA et al (2008) ESC guidelines for the diagnosis and treatment of acute and chronic heart failure 2008: the task force for the diagnosis and treatment of acute and chronic heart failure 2008 of the European Society of Cardiology. Developed in collaboration with the Heart Failure Association of the ESC (HFA) and endorsed by the European Society of Intensive Care Medicine (ESICM). Eur Heart J 29(19):2388–2442CrossRefPubMed Dickstein K, Cohen-Solal A, Filippatos G, McMurray JJ, Ponikowski P, Poole-Wilson PA et al (2008) ESC guidelines for the diagnosis and treatment of acute and chronic heart failure 2008: the task force for the diagnosis and treatment of acute and chronic heart failure 2008 of the European Society of Cardiology. Developed in collaboration with the Heart Failure Association of the ESC (HFA) and endorsed by the European Society of Intensive Care Medicine (ESICM). Eur Heart J 29(19):2388–2442CrossRefPubMed
9.
Zurück zum Zitat Diller GP, Dimopoulos K, Okonko D, Li W, Babu-Narayan SV, Broberg CS et al (2005) Exercise intolerance in adult congenital heart disease: comparative severity, correlates, and prognostic implication. Circulation 112(6):828–835CrossRefPubMed Diller GP, Dimopoulos K, Okonko D, Li W, Babu-Narayan SV, Broberg CS et al (2005) Exercise intolerance in adult congenital heart disease: comparative severity, correlates, and prognostic implication. Circulation 112(6):828–835CrossRefPubMed
10.
Zurück zum Zitat Duffie ER, Adams FA (1963) The use of the working capacity test in the evaluation of children with congenital heart disease. Pediatrics 32:757–768PubMed Duffie ER, Adams FA (1963) The use of the working capacity test in the evaluation of children with congenital heart disease. Pediatrics 32:757–768PubMed
11.
Zurück zum Zitat Dulfer K, Helbing WA, Duppen N et al (2014) Associations between exercise capacity, physical activity, and psychosocial functioning in children with congenital heart disease: a systematic review. Eur J Prev Cardiol 21(10):1200–1215CrossRefPubMed Dulfer K, Helbing WA, Duppen N et al (2014) Associations between exercise capacity, physical activity, and psychosocial functioning in children with congenital heart disease: a systematic review. Eur J Prev Cardiol 21(10):1200–1215CrossRefPubMed
12.
Zurück zum Zitat Dulfer K, Duppen N, Blom NA, Domburg RTV, Helbing WA, Verhulst FC (2014) Effects of exercise training on behavioral and emotional problems in adolescents with tetralogy of Fallot or a Fontan circulation: a randomized controlled trial. Int J Cardiol 172:e425–e427CrossRefPubMed Dulfer K, Duppen N, Blom NA, Domburg RTV, Helbing WA, Verhulst FC (2014) Effects of exercise training on behavioral and emotional problems in adolescents with tetralogy of Fallot or a Fontan circulation: a randomized controlled trial. Int J Cardiol 172:e425–e427CrossRefPubMed
13.
Zurück zum Zitat Dulfer K, Duppen N, Kuipers IM, Schokking M, van Domburg RT, Verhulst FC et al (2014) Aerobic exercise influences quality of life of children and youngsters with congenital heart disease: a randomized controlled trial. J Adolesc Health 55(1):65–72CrossRefPubMed Dulfer K, Duppen N, Kuipers IM, Schokking M, van Domburg RT, Verhulst FC et al (2014) Aerobic exercise influences quality of life of children and youngsters with congenital heart disease: a randomized controlled trial. J Adolesc Health 55(1):65–72CrossRefPubMed
14.
Zurück zum Zitat Duppen N, Takken T, Hopman MT, ten Harkel AD, Dulfer K, Utens EM et al (2013) Systematic review of the effects of physical exercise training programmes in children and young adults with congenital heart disease. Int J Cardiol 168(3):1779–1787CrossRefPubMed Duppen N, Takken T, Hopman MT, ten Harkel AD, Dulfer K, Utens EM et al (2013) Systematic review of the effects of physical exercise training programmes in children and young adults with congenital heart disease. Int J Cardiol 168(3):1779–1787CrossRefPubMed
15.
Zurück zum Zitat Frankenstein L, Nelles M, Hallerbach M, Dukic D, Fluegel A, Schellberg D et al (2007) Prognostic impact of peak VO2-changes in stable CHF on chronic beta-blocker treatment. Int J Cardiol 122(2):125–130CrossRefPubMed Frankenstein L, Nelles M, Hallerbach M, Dukic D, Fluegel A, Schellberg D et al (2007) Prognostic impact of peak VO2-changes in stable CHF on chronic beta-blocker treatment. Int J Cardiol 122(2):125–130CrossRefPubMed
16.
Zurück zum Zitat Fredriksen PM, Kahrs N, Blaasvaer S, Sigurdsen E, Gundersen O, Roeksund O et al (2000) Effect of physical training in children and adolescents with congenital heart disease. Cardiol Young 10:107–114PubMed Fredriksen PM, Kahrs N, Blaasvaer S, Sigurdsen E, Gundersen O, Roeksund O et al (2000) Effect of physical training in children and adolescents with congenital heart disease. Cardiol Young 10:107–114PubMed
17.
Zurück zum Zitat Higgins JPT, Green S (2006) The Cochrane Library. Issue 4. Cochrane handbook for systematic reviews of interventions 4.2.6. Wiley, Chichester Higgins JPT, Green S (2006) The Cochrane Library. Issue 4. Cochrane handbook for systematic reviews of interventions 4.2.6. Wiley, Chichester
19.
Zurück zum Zitat Maher CG, Sherrington C, Herbert RD, Moseley AM, Elkins M (2003) Reliability of the PEDro scale for rating of quality randomized controlled trials. Phys Ther 83(8):713–721PubMed Maher CG, Sherrington C, Herbert RD, Moseley AM, Elkins M (2003) Reliability of the PEDro scale for rating of quality randomized controlled trials. Phys Ther 83(8):713–721PubMed
20.
Zurück zum Zitat Mampuya WM (2012) Cardiac rehabilitation past, present and future: an overview. Cardiovasc Diagn Ther 2(1):38–49PubMedCentralPubMed Mampuya WM (2012) Cardiac rehabilitation past, present and future: an overview. Cardiovasc Diagn Ther 2(1):38–49PubMedCentralPubMed
21.
Zurück zum Zitat Mellion K, Uzark K, Cassedy A, Drotar D, Wernovsky G, Newburger JW et al (2014) Health-related quality of life outcomes in children and adolescents with congenital heart disease. J Pediatr 164(4):781–788CrossRefPubMed Mellion K, Uzark K, Cassedy A, Drotar D, Wernovsky G, Newburger JW et al (2014) Health-related quality of life outcomes in children and adolescents with congenital heart disease. J Pediatr 164(4):781–788CrossRefPubMed
22.
Zurück zum Zitat Moalla W, Maingourd Y, Gauthier R, Cahalin LP, Tabka Z, Ahmaidi S (2006) Effect of exercise training on respiratory muscle oxygenation in children with congenital heart disease. Eur J Cardiovasc Prev Rehabil 13:604–611CrossRefPubMed Moalla W, Maingourd Y, Gauthier R, Cahalin LP, Tabka Z, Ahmaidi S (2006) Effect of exercise training on respiratory muscle oxygenation in children with congenital heart disease. Eur J Cardiovasc Prev Rehabil 13:604–611CrossRefPubMed
23.
Zurück zum Zitat Moalla W, Elloumi M, Chamari K, Dupont G, Maingourd Y, Tabka Z et al (2012) Training effects on peripheral muscle oxygenation and performance in children with congenital heart diseases. Appl Physiol Nutr Metab 57:1–10 Moalla W, Elloumi M, Chamari K, Dupont G, Maingourd Y, Tabka Z et al (2012) Training effects on peripheral muscle oxygenation and performance in children with congenital heart diseases. Appl Physiol Nutr Metab 57:1–10
24.
Zurück zum Zitat Moher D, Liberati A, Tetzlaff J et al (2009) Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. BMJ 339:2535CrossRef Moher D, Liberati A, Tetzlaff J et al (2009) Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. BMJ 339:2535CrossRef
25.
Zurück zum Zitat Müller J, Ewert P, Hager A (2015) Only slow decline in exercise capacity in the natural history of patients with congenital heart disease: a longitudinal study in 522 patients. Eur J Prev Cardiol 22(1):113–118CrossRefPubMed Müller J, Ewert P, Hager A (2015) Only slow decline in exercise capacity in the natural history of patients with congenital heart disease: a longitudinal study in 522 patients. Eur J Prev Cardiol 22(1):113–118CrossRefPubMed
26.
Zurück zum Zitat Negura D, Micheletti A, Chessa M, Calaciura R, Saracino A, Butera G et al (2010) Cardiopulmonary exercise test in adults with congenital heart disease. Pediatr Med Chir 32(6):256–259PubMed Negura D, Micheletti A, Chessa M, Calaciura R, Saracino A, Butera G et al (2010) Cardiopulmonary exercise test in adults with congenital heart disease. Pediatr Med Chir 32(6):256–259PubMed
27.
Zurück zum Zitat Olivo SA, Macedo LG, Gadotti IN, Fuentes J, Stanton T, Magee DJ (2008) Scales to assess the quality of randomized controlled trials: a systematic review. Phys Ther 88(2):156–175CrossRefPubMed Olivo SA, Macedo LG, Gadotti IN, Fuentes J, Stanton T, Magee DJ (2008) Scales to assess the quality of randomized controlled trials: a systematic review. Phys Ther 88(2):156–175CrossRefPubMed
28.
Zurück zum Zitat Reybrouck T, Rogers R, Weymans M et al (1995) Serial cardiorespiratory exercise testing in patients with congenital heart disease. Eur J Pediatr 154:801–806CrossRefPubMed Reybrouck T, Rogers R, Weymans M et al (1995) Serial cardiorespiratory exercise testing in patients with congenital heart disease. Eur J Pediatr 154:801–806CrossRefPubMed
29.
Zurück zum Zitat Rhodes J, Curran TJ, Camil L, Rabideau N, Fulton DR, Gauthier NS et al (2006) Sustained effects of cardiac rehabilitation in children with serious congenital heart disease. Pediatrics 118:e586–e593CrossRefPubMed Rhodes J, Curran TJ, Camil L, Rabideau N, Fulton DR, Gauthier NS et al (2006) Sustained effects of cardiac rehabilitation in children with serious congenital heart disease. Pediatrics 118:e586–e593CrossRefPubMed
30.
Zurück zum Zitat Rhodes J, Ubeda Tikkanen A, Jenkins KJ (2010) Exercise testing and training in children with congenital heart disease. Circulation 122:1957–1967CrossRefPubMed Rhodes J, Ubeda Tikkanen A, Jenkins KJ (2010) Exercise testing and training in children with congenital heart disease. Circulation 122:1957–1967CrossRefPubMed
31.
Zurück zum Zitat Singh TP, Curran TJ, Rhodes EJ (2007) Cardiac rehabilitation improves heart rate recovery following peak exercise in children with repaired congenital heart disease. Pediatr Cardiol 28:276–279CrossRefPubMed Singh TP, Curran TJ, Rhodes EJ (2007) Cardiac rehabilitation improves heart rate recovery following peak exercise in children with repaired congenital heart disease. Pediatr Cardiol 28:276–279CrossRefPubMed
32.
Zurück zum Zitat Tikkanen AU, Oyaga AR, Riaño OA, Álvaro EM, Rhodes J (2012) Paediatric cardiac rehabilitation in congenital heart disease: a systematic review. Cardiol Young 22(3):241–250CrossRefPubMed Tikkanen AU, Oyaga AR, Riaño OA, Álvaro EM, Rhodes J (2012) Paediatric cardiac rehabilitation in congenital heart disease: a systematic review. Cardiol Young 22(3):241–250CrossRefPubMed
33.
Zurück zum Zitat Verhagen AP, de Vet HCW, de Bie RA, Kessels AGH, Boers M, Bouter LM et al (1998) The Delphi List: a criteria list for quality assessment of randomized clinical trials for conducting systematic reviews developed by Delphi consensus. J Clin Epidemiol 51(12):1235–1241CrossRefPubMed Verhagen AP, de Vet HCW, de Bie RA, Kessels AGH, Boers M, Bouter LM et al (1998) The Delphi List: a criteria list for quality assessment of randomized clinical trials for conducting systematic reviews developed by Delphi consensus. J Clin Epidemiol 51(12):1235–1241CrossRefPubMed
Metadaten
Titel
Impact of Exercise Training in Aerobic Capacity and Pulmonary Function in Children and Adolescents After Congenital Heart Disease Surgery: A Systematic Review with Meta-analysis
verfasst von
Mansueto Gomes-Neto
Micheli Bernardone Saquetto
Cassio Magalhães da Silva e Silva
Cristiano Sena Conceição
Vitor Oliveira Carvalho
Publikationsdatum
01.02.2016
Verlag
Springer US
Erschienen in
Pediatric Cardiology / Ausgabe 2/2016
Print ISSN: 0172-0643
Elektronische ISSN: 1432-1971
DOI
https://doi.org/10.1007/s00246-015-1270-x

Weitere Artikel der Ausgabe 2/2016

Pediatric Cardiology 2/2016 Zur Ausgabe

Update Kardiologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.