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European Radiology
Erschienen in:

08.08.2023 | Gastrointestinal

Impact of fat on the apparent T1 value of the liver: assessment by water-only derived T1 mapping

verfasst von: Mayumi Higashi, Masahiro Tanabe, Masatoshi Yamane, Mahesh B. Keerthivasan, Hiroshi Imai, Teppei Yonezawa, Michihiro Nakamura, Katsuyoshi Ito

Erschienen in: European Radiology | Ausgabe 10/2023

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Abstract

Objectives

To determine the impact of fat on the apparent T1 value of the liver using water-only derived T1 mapping.

Methods

3-T MRI included 2D Look-Locker T1 mapping and proton density fat fraction (PDFF) mapping. T1 values of the liver were compared among T1 maps obtained by in-phase (IP), opposed-phase (OP), and Dixon water sequences using paired t-test. The correlation between T1 values of the liver on each T1 map and PDFF was assessed using Spearman correlation coefficient. The absolute differences between T1 value of the liver on Dixon water images and that on IP or OP images were also correlated with PDFF.

Results

One hundred sixty-two patients (median age, 70 [range, 24–91] years, 90 men) were retrospectively evaluated. The T1 values of the liver on each T1 map were significantly different (p < 0.001). The T1 value of the liver on IP images was significantly negatively correlated with PDFF (r =  − 0.438), while the T1 value of the liver on OP images was slightly positively correlated with PDFF (r = 0.164). The T1 value of the liver on Dixon water images was slightly negatively correlated with PDFF (r =  − 0.171). The absolute differences between T1 value of the liver on Dixon water images and that on IP or OP images were significantly correlated with PDFF (r = 0.606, 0.722; p < 0.001).

Conclusion

Fat correction for the apparent T1 value by water-only derived T1 maps will be helpful for accurately evaluating the T1 value of the liver.

Clinical relevance statement

Fat-corrected T1 mapping of the liver with the water component only obtained from the 2D Dixon Look-Locker sequence could be useful for accurately evaluating the T1 value of the liver without the impact of fat in daily clinical practice.

Key Points

• The T1 values of the liver on the conventional T1 maps are significantly affected by the presence of fat.
• The apparent T1 value of the liver on water-only derived T1 maps would be slightly impacted by the presence of fat.
• Fat correction for the apparent T1 values is necessary for the accurate assessment of the T1 values of the liver.
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Metadaten
Titel
Impact of fat on the apparent T1 value of the liver: assessment by water-only derived T1 mapping
verfasst von
Mayumi Higashi
Masahiro Tanabe
Masatoshi Yamane
Mahesh B. Keerthivasan
Hiroshi Imai
Teppei Yonezawa
Michihiro Nakamura
Katsuyoshi Ito
Publikationsdatum
08.08.2023
Verlag
Springer Berlin Heidelberg
Erschienen in
European Radiology / Ausgabe 10/2023
Print ISSN: 0938-7994
Elektronische ISSN: 1432-1084
DOI
https://doi.org/10.1007/s00330-023-10052-0

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