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Erschienen in: European Journal of Clinical Microbiology & Infectious Diseases 3/2019

24.01.2019 | Original Article

Impact of health care–associated community-onset cellulitis in Korea: a multicenter study

verfasst von: Seong Yeon Park, Tark Kim, Seong-Ho Choi, Jiwon Jung, Shi Nae Yu, Hyo-Lim Hong, Yong Kyun Kim, Se Yoon Park, Eun Hee Song, Ki-Ho Park, Oh-Hyun Cho, Sang Ho Choi, Yee Gyung Kwak, and the Korean SSTI (Skin and Soft Tissue Infection) Study Group

Erschienen in: European Journal of Clinical Microbiology & Infectious Diseases | Ausgabe 3/2019

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Abstract

We conducted a multicenter study to determine the clinical and microbiological characteristics of health care–associated (HCA) cellulitis in Korea. We retrospectively reviewed the medical records of patients who had been diagnosed with community-onset cellulitis. Of the 2208 cellulitis patients, 232 (10.5%) had HCA cellulitis, 1243 (56.3%) patients were hospitalized, and 15 (0.7%) died in hospital. Compared with community-acquired (CA) cellulitis, patients with HCA cellulitis were older and more frequently presented with comorbidity and septic shock. A total of 355 microorganisms were isolated from 314 patients (14.2%). Staphylococcus aureus (134 isolates) was the most common organism, followed by Streptococcus spp. (86 isolates) and Gram-negative fermenters (58 isolates). Methicillin-resistant S. aureus (MRSA) accounted for 29.1% (39/134) of S. aureus infections. None of the Gram-negative fermenters were resistant to carbapenem. The antibiotic susceptibility pattern of isolated microorganisms was not different between HCA and CA cellulitis. In patients with HCA cellulitis, S. aureus (11.2% [26/232] vs. 5.5% [108/1976], p = 0.001), including MRSA (4.3% [10/232] vs. 1.5% [29/1976], p = 0.003) and Gram-negative fermenters (6.0% [14/232] vs. 2.3% [44/1976], p = 0.002), were more common causative organisms than in CA-cellulitis patients. Age ≥ 65 years, septic shock, and HCA infection were statistically significant factors associated with in-hospital mortality.
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Metadaten
Titel
Impact of health care–associated community-onset cellulitis in Korea: a multicenter study
verfasst von
Seong Yeon Park
Tark Kim
Seong-Ho Choi
Jiwon Jung
Shi Nae Yu
Hyo-Lim Hong
Yong Kyun Kim
Se Yoon Park
Eun Hee Song
Ki-Ho Park
Oh-Hyun Cho
Sang Ho Choi
Yee Gyung Kwak
and the Korean SSTI (Skin and Soft Tissue Infection) Study Group
Publikationsdatum
24.01.2019
Verlag
Springer Berlin Heidelberg
Erschienen in
European Journal of Clinical Microbiology & Infectious Diseases / Ausgabe 3/2019
Print ISSN: 0934-9723
Elektronische ISSN: 1435-4373
DOI
https://doi.org/10.1007/s10096-018-03456-0

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