The health of mothers and their newborns is intricately related. The weight of the infant at birth is a powerful predictor of infant growth and survival, and is considered to be partly dependent on maternal health and nutrition during pregnancy. We conducted a longitudinal study in an urban community within Karachi to determine maternal predictors of newborn birth weight.
Four hundred pregnant women were enrolled in the study during the period 2011–2013. Data related to symptoms of acute respiratory illness (fever, cough, difficulty breathing, runny nose, sore throat, headache, chills, and myalgia/lethargy) in the pregnant women were collected weekly until delivery. Birth weight of the newborn was recorded within 14 days of delivery and the weight of <2.5 kg was classified as low birth weight (LBW).
A total of 9,853 symptom episodes were recorded of fever, cough, difficulty breathing, runny nose, sore throat, headache, chills, myalgias/lethargy in the enrolled pregnant women during the study. Out of 243 pregnant women whose newborns were weighed within 14 days of birth, LBW proportion was 21% (n = 53). On multivariate analysis, independent significant risk factors noted for delivering LBW babies were early pregnancy weight of < 57.5 kg [odds ratio adjusted (ORadj) = 5.1, 95% CI: (1.3, 19.9)] and gestational age [ORadj = 0.3, 95% CI (0.2, 0.7) for every one week increase in gestational age]. Among mothers with high socioeconomic status (SES), every 50-unit increase in the number of episodes of respiratory illness/100 weeks of pregnancy had a trend of association with an increased risk of delivering LBW infants [ORadj = 1.7, 95% CI: (1.0, 3.1)]. However, among mothers belonging to low SES, there was no association of the number of episodes of maternal respiratory illness during pregnancy with infants having LBW [ORadj = 0.9, 95% CI: (0.5, 3.5)].
While overall respiratory illnesses during pregnancy did not impact newborn weight in our study, we found this trend in the sub-group of mothers belonging to the higher SES. Whether this is because in mothers belonging to lower SES, the effects of respiratory illnesses were overshadowed by other risk factors associated with poverty need to be further studied.
World Health O. The World Health Report 2005. Make every mother and child count. Geneva: World Health Organization; 2005. p. 2005.
Larson L, Mehta N, Paglia MJ. 1 Pulmonary disease in pregnancy. de Swiet's Medical Disorders in Obstetric Practice. 5th Edition, MA. USA: Wiley-Blackwell; 2010. p. 1-47
Rasmussen SA, Jamieson DJ, MacFarlane K, Cragan JD, Williams J, Henderson Z. Pandemic influenza and pregnant women: summary of a meeting of experts. Am J Public Health. 2009;99(S2):248-54.
A study done by Centers for Disease Control and Prevention (CDC). Maternal, C.D.C and infant outcomes among severely ill pregnant and postpartum women with 2009 pandemic influenza A (H1N1)--United States, April 2009-August 2010. MMWR Morb Mortal Wkly Rep. 2011;60(35):1193–196.
SPSS 15.0 for Windows. Chicago: SPSS Inc (Release 15.0.0 .2006).
Johnson RA, Wichern DW. Applied multivariate statistical analysis, vol. 5. Upper Saddle River: Prentice hall; 2002.
Hosmer DW, Lemeshow S. Applied Logistic Regression. 2000. 330–9
Zakar R, Zakar MZ, Aqil N, Nasrullah M. Paternal factors associated with neonatal deaths and births with low weight: evidence from Pakistan demographic and health survey 2006–2007. Maternal and child health journal. 2015;19(7):1634-42.
- Impact of maternal respiratory infections on low birth weight - a community based longitudinal study in an urban setting in Pakistan
William A. Petri
Molly A. Hughes
- BioMed Central
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