Insomnia and migraine are closely related; insomnia aggravates migraine symptoms. This study was conducted to investigate the impact of migraine on the clinical presentation of insomnia symptoms.
The data of the Korean Headache-Sleep Study (KHSS) were used in the present study. The KHSS is a nation-wide cross-sectional population-based survey regarding headache and sleep in Korean adults aged 19 to 69 years. If a participant’s Insomnia Severity Index (ISI) score ≥ 10, she/he was classified as having insomnia. The clinical presentation of insomnia symptoms was assessed using total and subcomponent scores of the ISI.
Of 2695 participants, 290 (10.8%) and 143 (5.3%) individuals were assigned as having insomnia and migraine, respectively. The proportions of migraine (12.8% vs. 4.4%, p < 0.001) and non-migraine headache (59.0% vs. 39.9%, p < 0.001) were higher among individuals with insomnia compared to those without insomnia. Among participants with insomnia, total ISI scores were not significantly different among participants with migraine, non-migraine, and non-headache [median and interquartile range: 13.0 (11.0–17.5) vs. 13.0 (11.0–17.5) vs. 12.0 (11.0–16.0), p = 0.245]. ISI scores for noticeability of sleep problems to others were significantly higher among participants with migraine [3.0 (2.0–4.0) vs. 2.0 (2.0–3.0), p = 0.011] and non-migraine headache [3.0 (2.0–4.0) vs. 2.0 (2.0–3.0), p = 0.001] compared to those without headache history. Other ISI subcomponent scores did not significantly differ between headache status groups.
Participants with insomnia had an increased risk of migraine and non-migraine headache compared to those without insomnia. Among participants with insomnia, overall insomnia severity was not significantly influenced by the headache status.
Stovner L, Hagen K, Jensen R, Katsarava Z, Lipton R, Scher A, Steiner T, Zwart JA (2007) The global burden of headache: a documentation of headache prevalence and disability worldwide. Cephalalgia 27(3):193–210 CrossRef
Ohayon MM (2002) Epidemiology of insomnia: what we know and what we still need to learn. Sleep Med Rev 6(2):97–111 CrossRef
Morin CM, Jarrin DC (2013) Epidemiology of insomnia: prevalence, course, risk factors, and public health burden. Sleep Med Clin 8(3):281–297 CrossRef
Headache Classification Subcommittee of the International Headache S (2004) The international classification of headache disorders: 2nd edition. Cephalalgia : an international journal of headache 24 Suppl 1:9–160
Bastien CH, Vallieres A, Morin CM (2001) Validation of the insomnia severity index as an outcome measure for insomnia research. Sleep Med 2(4):297–307 CrossRef
Schulte LH, Allers A, May A (2017) Hypothalamus as a mediator of chronic migraine: evidence from high-resolution fMRI. Neurology 88(21):2011–2016 CrossRef
Stone KC, Taylor DJ, McCrae CS, Kalsekar A, Lichstein KL (2008) Nonrestorative sleep. Sleep Med Rev 12(4):275–288 CrossRef
White KP, Speechley M, Harth M, Ostbye T (1999) The London fibromyalgia epidemiology study: comparing the demographic and clinical characteristics in 100 random community cases of fibromyalgia versus controls. J Rheumatol 26(7):1577–1585 PubMed
Li K, Sun X, Cui L (2008) A survey on sleep quality of the people aged over 18-years-old in Hebei Province. Chin Ment Health J 22(4):302
Yeo BK, Perera IS, Kok LP, Tsoi WF (1996) Insomnia in the community. Singap Med J 37(3):282–284
- Impact of migraine on the clinical presentation of insomnia: a population-based study
Kwang Ik Yang
Min Kyung Chu
- Springer Milan
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