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Current Hepatology Reports

Erschienen in:

27.04.2017 | Hepatitis B (J Lim, Section Editor)

Impact of Non-alcoholic Fatty Liver Disease on Chronic Hepatitis B Infection

verfasst von: Anthony W.H. Chan, Grace L.H. Wong, Vincent W.S. Wong

Erschienen in: Current Hepatology Reports | Ausgabe 2/2017

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Abstract

Purpose of review

Both chronic hepatitis B (CHB) and non-alcoholic fatty liver disease (NAFLD) are frequent liver diseases with substantial morbidity and mortality. How often do these two diseases occur together? Does hepatitis B virus protect or promote concurrent fatty liver? How does concurrent fatty liver influence the clinical outcomes of CHB? We summarized the latest evidence to tackle all these clinically significant questions.

Recent findings

Concurrent fatty liver in CHB without significant alcohol intake is a common and increasingly alarming problem. Patients with CHB have a lower chance of fatty liver than the general population, but the underlying mechanism remains to be further explored. Clinical impacts of concurrent fatty liver among CHB patients, in terms of treatment response, fibrosis and cirrhosis progression, liver cancer risk, and mortality, are still debatable.

Summary

Concurrent fatty liver in CHB is a common and clinically relevant condition.

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Titel: Impact of Non-alcoholic Fatty Liver Disease on Chronic Hepatitis B Infection
verfasst von: Anthony W.H. Chan
Grace L.H. Wong
Vincent W.S. Wong
Publikationsdatum: 27.04.2017
Verlag: Springer US
Erschienen in: Current Hepatology Reports / Ausgabe 2/2017
Elektronische ISSN: 2195-9595
DOI: https://doi.org/10.1007/s11901-017-0340-3

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Impact of Non-alcoholic Fatty Liver Disease on Chronic Hepatitis B Infection

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