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Cardiovascular Intervention and Therapeutics

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19.10.2017 | Original Article

Impact of previous drug-eluting stent restenosis in non-left main coronary artery lesions on long-term outcomes after left main coronary artery stenting: an observation from the AOI-LMCA registry

verfasst von: Hirooki Higami, Mamoru Toyofuku, Takeshi Morimoto, Masanobu Ohya, Yasushi Fuku, Kyohei Yamaji, Hiromi Muranishi, Yuhei Yamaji, Koji Nishida, Daisuke Furukawa, Tomohisa Tada, Euihong Ko, Kenji Ando, Hiroki Sakamoto, Takashi Tamura, Kazuya Kawai, Kazushige Kadota, Takeshi Kimura, On Behalf of the AOI LMCA Stenting Registry Investigators

Erschienen in: Cardiovascular Intervention and Therapeutics | Ausgabe 4/2018

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Abstract

We hypothesized that patients who had previous target-lesion revascularization (TLR) for DES restenosis in non-left main coronary artery (LMCA) lesions might have a higher risk for restenosis after subsequent DES implantation for a de novo unprotected LMCA lesion. Among 1809 patients enrolled in the Assessing Optimal Percutaneous Coronary Intervention for LMCA (AOI-LMCA) registry, which is a retrospective 6-centre registry of consecutive patients undergoing LMCA stenting in Japan, 251 patients with previous DES implantation for non-LMCA lesions were subdivided into the 2 groups with (N = 56) or without (N = 195) previous TLR in non-LMCA lesions. The risk for TLR for LMCA was neutral between the prior TLR for DES restenosis group and the no prior TLR for DES restenosis group [hazard ratio (HR) 0.99, 95% confidence interval (CI) 0.44–2.02, P = 0.98]. The risks for both TLR caused by restenosis of the LMCA main branch, and second TLR for restenosis after first TLR for LMCA were also neutral between the 2 groups (HR 0.42, 95% CI 0.10–1.25, P = 0.13, and HR 0.59, 95% CI 0.03–3.63, P = 0.60, respectively). In conclusion, prior TLR for DES restenosis in non-LMCA lesions was not associated with worse long-term clinical outcomes after DES implantation for de novo unprotected LMCA lesions.

Clinical Trial Registration: Assessing Optimal Percutaneous Coronary Intervention for Left Main Coronary Artery Stenting Registry (AOI LMCA Stenting Registry). http://www.umin.ac.jp/ctr/index/htm/. Unique Identifier: UMIN000014706.

Moses JW, Leon MB, Popma JJ, Fitzgerald PJ, Holmes DR, O’Shaughnessy C, Caputo RP, Kereiakes DJ, Williams DO, Teirstein PS, Jaeger JL, Kuntz RE. Sirolimus-eluting stents versus standard stents in patients with stenosis in a native coronary artery. N Engl J Med. 2003; 349:1315–23.CrossRef

Stone GW, Ellis SG, Cox DA, Hermiller J, O’Shaughnessy C, Mann JT, Turco M, Caputo R, Bergin P, Greenberg J, Popma JJ, Russell ME. TAXUS-IV Investigators. A polymer-based, paclitaxel-eluting stent in patients with coronary artery disease. N Engl J Med. 2004;350:221–31.CrossRef

Toyofuku M, Kimura T, Morimoto T, Hayashi Y, Ueda H, Kawai K, Nozaki Y, Hiramatsu S, Miura A, Yokoi Y, Toyoshima S, Nakashima H, Haze K, Tanaka M, Take S, Saito S, Isshiki T, Mitsudo K. Three-year outcomes after sirolimus-eluting stent implantation for unprotected left main coronary artery disease: insights from the j-Cypher registry. Circulation. 2009;120:1866–74.CrossRef

Toyofuku M, Kimura T, Morimoto T, Hayashi Y, Shiode N, Okimoto T, Otsuka M, Tamekiyo H, Tamura T, Kadota K, Inoue K, Mitsudo K. Comparison of target-lesion revascularisation between left main coronary artery bifurcations and left anterior descending coronary artery bifurcations using the one and two stent approach with sirolimus-eluting stents. EuroIntervention. 2011;7:796–804.CrossRef

Park D-W, Seung KB, Kim Y-H, Lee J-Y, Kim W-J, Kang S-J, Lee S-W, Lee CW, Park S-W, Yun S-C, Gwon H-C, Jeong M-H, Jang Y-S, Kim H-S, Kim PJ, Seong I-W, Park HS, Ahn T, Chae I-H, Tahk S-J, Chung W-S, Park S-J. Long-term safety and efficacy of stenting versus coronary artery bypass grafting for unprotected left main coronary artery disease: 5-year results from the MAIN-COMPARE (revascularization for unprotected left main coronary artery stenosis: comparison of P). J Am Coll Cardiol. 2010;56:117–24.CrossRef

Chieffo A, Magni V, Latib A, Maisano F, Ielasi A, Montorfano M, Carlino M, Godino C, Ferraro M, Calori G, Alfieri O, Colombo A. 5-year outcomes following percutaneous coronary intervention with drug-eluting stent implantation versus coronary artery bypass graft for unprotected left main coronary artery lesions the Milan experience. JACC Cardiovasc Interv. 2010;3:595–601.CrossRef

Park S-J, Park S, Hong M-K, Lee CW, Lee J-H, Kim J-J, Jang YS, Shin E-K, Yoshida Y, Tamura T, Kimura T, Nobuyoshi M. Long-term (three-year) outcomes after stenting of unprotected left main coronary artery stenosis in patients with normal left ventricular function. Am J Cardiol. 2003;91:12–6.CrossRef

Higami H, Shiomi H, Niki S, Tazaki J, Imai M, Saito N, Makiyama T, Shizuta S, Shioi T, Ono K, Kimura T. Long-term clinical outcomes after sirolimus-eluting stent implantation for unprotected left main coronary artery disease. Cardiovasc Interv Ther. 2015;30:189–97.CrossRef

Morice M-C, Serruys PW, Kappetein AP, Feldman TE, Stahle E, Colombo A, Mack MJ, Holmes DR, Torracca L, van Es G-A, Leadley K, Dawkins KD, Mohr F. Outcomes in patients with de novo left main disease treated with either percutaneous coronary intervention using paclitaxel-eluting stents or coronary artery bypass Graft treatment in the synergy between percutaneous coronary intervention with TAXUS and C. Circulation. 2010;121:2645–53.CrossRef

10.

Stone GW, Sabik JF, Serruys PW, Simonton CA, Généreux P, Puskas J, Kandzari DE, Morice M-C, Lembo N, Brown WM, Taggart DP, Banning A, Merkely B, Horkay F, Boonstra PW, van Boven AJ, Ungi I, Bogáts G, Mansour S, Noiseux N, Sabaté M, Pomar J, Hickey M, Gershlick A, Buszman P, Bochenek A, Schampaert E, Pagé P, Dressler O, Kosmidou I, Mehran R, Pocock SJ, Kappetein AP. Everolimus-eluting stents or bypass surgery for left main coronary artery disease. N Engl J Med. 2016;375:2223–35.CrossRef

11.

Authors/Task Force Members, Windecker S, Kolh P, Alfonso F, Collet J-P, Cremer J, Falk V, Filippatos G, Hamm C, Head SJ, Jüni P, Kappetein AP, Kastrati A, Knuuti J, Landmesser U, Laufer G, Neumann F-J, Richter DJ, Schauerte P, Sousa Uva M, Stefanini GG, Taggart DP, Torracca L, Valgimigli M, Wijns W, Witkowski A. 2014 ESC/EACTS Guidelines on myocardial revascularization: The Task Force on Myocardial Revascularization of the European Society of Cardiology (ESC) and the European Association for Cardio-Thoracic Surgery (EACTS) developed with the special contribution. Eur Heart J. 2014;35:2541–619.CrossRef

12.

Takagi K, Ielasi A, Shannon J, Latib A, Godino C, Davidavicius G, Mussardo M, Ferrarello S, Figini F, Carlino M, Montorfano M, Chieffo A, Nakamura S, Colombo A. Clinical and procedural predictors of suboptimal outcome after the treatment of drug-eluting stent restenosis in the unprotected distal left main stem: The Milan and New-Tokyo (MITO) registry. Circ Cardiovasc Interv. 2012;5:491–8.CrossRef

13.

Mishkel GJ, Moore AL, Markwell S, Shelton MC, Shelton ME. Long-Term outcomes after management of restenosis or thrombosis of drug-eluting stents. J Am Coll Cardiol. 2007;49:181–4.CrossRef

14.

Sheiban I, Sillano D, Biondi-Zoccai G, Chieffo A, Colombo A, Vecchio S, Margheri M, Gunn JP, Raina T, Liistro F, Bolognese L, Lee MS, Tobis J, Moretti C. Incidence and management of restenosis after treatment of unprotected left main disease with drug-eluting Stents. 70 restenotic cases from a cohort of 718 patients: FAILS (Failure in Left Main Study). J Am Coll Cardiol. 2009;54:1131–6.CrossRef

15.

Nakagawa Y, Kimura T, Morimoto T, Nomura M, Saku K, Haruta S, Muramatsu T, Nobuyoshi M, Kadota K, Fujita H, Tatami R, Shiode N, Nishikawa H, Shibata Y, Miyazaki S, Murata Y, Honda T, Kawasaki T, Doi O, Hiasa Y, Hayashi Y, Matsuzaki M, Mitsudo K. Incidence and risk factors of late target lesion revascularization after sirolimus-eluting stent implantation (3-year follow-up of the j-Cypher registry). Am J Cardiol. 2010;106:329–36.CrossRef

16.

Lee J-Y, Park D-W, Kim Y-H, Yun S-C, Kim W-J, Kang S-J, Lee S-W, Lee C-W, Park S-W, Park S-J. Incidence, predictors, treatment, and long-term prognosis of patients with restenosis after drug-eluting stent implantation for unprotected left main coronary artery disease. J Am Coll Cardiol. 2011;57:1349–58.CrossRef

17.

Lemos PA, Serruys PW, Van Domburg RT, Saia F, Arampatzis CA, Hoye A, Degertekin M, Tanabe K, Daemen J, Liu TKK, McFadden E, Sianos G, Hofma SH, Smits PC, Van Der Giessen WJ, De Feyter PJ. Unrestricted utilization of sirolimus-eluting stents compared with conventional bare stent implantation in the “real world”: the rapamycin-eluting stent evaluated at Rotterdam Cardiology Hospital (RESEARCH) registry. Circulation. 2004;109:190–5.CrossRef

18.

Tada T, Kimura T, Morimoto T, Ono K, Furukawa Y, Nakagawa Y, Nakashima H, Ito A, Siode N, Namura M, Inoue N, Nishikawa H, Nakao K, Mitsudo K, j-Cypher Registry Investigators. Comparison of three-year clinical outcomes after sirolimus-eluting stent implantation among insulin-treated diabetic, non-insulin-treated diabetic, and non-diabetic patients from j-Cypher registry. Am J Cardiol. 2011;107:1155–62.CrossRef

19.

Cassese S, Byrne RA, Tada T, Pinieck S, Joner M, Ibrahim T, King LA, Fusaro M, Laugwitz K-L, Kastrati A. Incidence and predictors of restenosis after coronary stenting in 10 004 patients with surveillance angiography. Heart. 2014;100:153–9.CrossRef

20.

Nishida K, Kimura T, Kawai K, Miyano I, Nakaoka Y, Yamamoto S, Kaname N, Seki S, Kubokawa S, Fukatani M, Hamashige N, Morimoto T, Mitsudo K. Comparison of outcomes using the sirolimus-eluting stent in calcified versus non-calcified native coronary lesions in patients on-versus not on-chronic hemodialysis (from the j-Cypher registry). Am J Cardiol. 2013;112:647–55.CrossRef

21.

Ikari Y, Tanabe K, Koyama Y, Kozuma K, Sano K, Isshiki T, Katsuki T, Kimura K, Yamane M, Takahashi N, Hibi K, Hasegawa K, Ishiwata S, Kiyooka T, Yokoi H, Uehara Y, Hara K. Sirolimus eluting coronary stent implantation in patients on maintenance hemodialysis—the OUCH Study (outcome of cypher stent in hemodialysis patients). Circ J. 2012;76:1856–63.CrossRef

22.

Ohya M, Kadota K, Toyofuku M, Morimoto T, Higami H, Fuku Y, Yamaji K, Muranishi H, Yamaji Y, Nishida K, Furukawa D, Tada T, Ko E, Ando K, Sakamoto H, Tamura T, Kawai K, Kimura T, AOI LMCA Stenting Registry Investigators. Long-term outcomes after stent implantation for left main coronary artery (from the multicenter assessing optimal percutaneous coronary intervention for left main coronary artery stenting registry). Am J Cardiol. 2016;119:355–64.CrossRef

23.

Serruys PW, Unger F, Sousa JE, Jatene A, Bonnier HJ, Schönberger JP, Buller N, Bonser R, van den Brand MJ, van Herwerden LA, Morel MA, van Hout BA. Comparison of coronary-artery bypass surgery and stenting for the treatment of multivessel disease. N Engl J Med. 2001;344:1117–24.CrossRef

24.

Cutlip DE, Windecker S, Mehran R, Boam A, Cohen DJ, van Es G-A, Steg PG, Morel M, Mauri L, Vranckx P, McFadden E, Lansky A, Hamon M, Krucoff MW, Serruys PW. Clinical end points in coronary stent trials: a case for standardized definitions. Circulation. 2007;115:2344–51.CrossRef

25.

Diacovo TG, Roth SJ, Buccola JM, Bainton DF, Springer TA. Neutrophil rolling, arrest, and transmigration across activated, surface-adherent platelets via sequential action of P-selectin and the beta 2-integrin CD11b/CD18. Blood. 1996;88:146–57.PubMed

26.

Rogers C, Edelman ER, Simon DI. A mAb to the beta2-leukocyte integrin Mac-1 (CD11b/CD18) reduces intimal thickening after angioplasty or stent implantation in rabbits. Proc Natl Acad Sci USA. 1998;95:10134–9.CrossRef

27.

Joner M, Finn AV, Farb A, Mont EK, Kolodgie FD, Ladich E, Kutys R, Skorija K, Gold HK, Virmani R. Pathology of drug-eluting stents in humans. delayed healing and late thrombotic risk. J Am Coll Cardiol. 2006;48:193–202.CrossRef

28.

Virmani R, Guagliumi G, Farb A, Musumeci G, Grieco N, Motta T, Mihalcsik L, Tespili M, Valsecchi O, Kolodgie FD. Localized hypersensitivity and late coronary thrombosis secondary to a sirolimus-eluting stent: should we be cautious? Circulation. 2004;109:701–5.CrossRef

29.

Nakazawa G, Otsuka F, Nakano M, Vorpahl M, Yazdani SK, Ladich E, Kolodgie FD, Finn AV, Virmani R. The pathology of neoatherosclerosis in human coronary implants bare-metal and drug-eluting stents. J Am Coll Cardiol. 2011;57:1314–22.CrossRef

30.

Towae F, Zahn R, Zeymer U. Repeat late instent-stenosis after an interval of four years in the same lesion after bare-metal and drug-eluting stent: a case report. Cases J. 2009;2:9407.CrossRef

31.

Middlebrooks EH, Panda M. Multiple recurrent stent thrombosis in a patient with coexisting clopidogrel resistance and increased anticardiolipin antibodies: a case report. Case Rep Med. 2010;2010:974149.CrossRef

32.

Abergel E, Beyar R, Roguin A. Repeat in-stent restenosis of drug-eluting stents in a bifurcation treated successfully with kissing drug eluting balloons. Cardiovasc Revasc Med. 2013;14:106–8.CrossRef

33.

Bresee SJ, Jacobs AK, Garber GR, Ruocco NA, Mills RM, Bergelson BA, Ryan TJ, Faxon DP. Prior restenosis predicts restenosis after coronary angioplasty of a new significant narrowing. Am J Cardiol. 1991;68:1158–62.CrossRef

34.

Lemos PA, Van Mieghem CAG, Arampatzis CA, Hoye A, Ong ATL, McFadden E, Sianos G, Van Der Giessen WJ, De Feyter PJ, Van Domburg RT, Serruys PW. Post-sirolimus-eluting stent restenosis treated with repeat percutaneous intervention: late angiographic and clinical outcomes. Circulation. 2004;109:2500–2.CrossRef

35.

Chieffo A, Stankovic G, Bonizzoni E, Tsagalou E, Iakovou I, Montorfano M, Airoldi F, Michev I, Sangiorgi MG, Carlino M, Vitrella G, Colombo A. Early and mid-term results of drug-eluting stent implantation in unprotected left main. Circulation. 2005;111:791–5.CrossRef

36.

Price MJ, Cristea E, Sawhney N, Kao JA, Moses JW, Leon MB, Costa RA, Lansky AJ, Teirstein PS. Serial angiographic follow-up of sirolimus-eluting stents for unprotected left main coronary artery revascularization. J Am Coll Cardiol. 2006;47:871–7.CrossRef

37.

Kim Y-H, Park S-W, Hong M-K, Park D-W, Park K-M, Lee B-K, Song J-M, Han K-H, Lee CW, Kang D-H, Song J-K, Kim J-J, Park S-J. Comparison of simple and complex stenting techniques in the treatment of unprotected left main coronary artery bifurcation stenosis. Am J Cardiol. 2006;97:1597–601.CrossRef

Titel: Impact of previous drug-eluting stent restenosis in non-left main coronary artery lesions on long-term outcomes after left main coronary artery stenting: an observation from the AOI-LMCA registry
verfasst von: Hirooki Higami
Mamoru Toyofuku
Takeshi Morimoto
Masanobu Ohya
Yasushi Fuku
Kyohei Yamaji
Hiromi Muranishi
Yuhei Yamaji
Koji Nishida
Daisuke Furukawa
Tomohisa Tada
Euihong Ko
Kenji Ando
Hiroki Sakamoto
Takashi Tamura
Kazuya Kawai
Kazushige Kadota
Takeshi Kimura
On Behalf of the AOI LMCA Stenting Registry Investigators
Publikationsdatum: 19.10.2017
Verlag: Springer Japan
Erschienen in: Cardiovascular Intervention and Therapeutics / Ausgabe 4/2018
Print ISSN: 1868-4300
Elektronische ISSN: 1868-4297
DOI: https://doi.org/10.1007/s12928-017-0497-2

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Impact of previous drug-eluting stent restenosis in non-left main coronary artery lesions on long-term outcomes after left main coronary artery stenting: an observation from the AOI-LMCA registry

Abstract

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