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Erschienen in:

05.08.2023 | Original Paper

Impact of the COVID-19 Pandemic on the PrEP Cascade at Two Veterans Affairs Healthcare Systems

verfasst von: Omar Harfouch, Emily Comstock, Roman Kaplan, Debra Benator, Heather Rivasplata, Eleanor Wilson

Erschienen in: AIDS and Behavior | Ausgabe 4/2024

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Abstract

Overall, fewer Veterans were eligible for PrEP in 2020, compared to 2019, and 2018 (Maryland Veterans Affairs Health Care System- MVAHCS-: n = 890 (2020), n = 1533 (2019); Washington DC Veterans Affairs Medical Center -DC VAMC- n = 1119 (2020), n = 1716 (2019)). While the proportion of Veterans engaged in PrEP out of those eligible for PrEP increased in 2020 compared to 2019 at both sites (MVAHCS: 5.73% (2020) vs. 3.39% (2019) p-value = 0.006; F = 7.58, and DC VAMC: 15.91% (2020) vs. 9.38% (2019) p-value < 0.001; F = 27.64), the absolute number of Veterans engaged in PrEP remained unchanged (MVAHCS n = 51 (2020) and n = 52 (2019); DC VAMC n = 178 (2020) and n = 161 (2019)). Engagement in PrEP was significantly lower among Black Veterans compared to White Veterans at the DC VAMC across all FY with a widening gap in 2020. Cisgender women were less likely to be engaged in PrEP compared to cisgender men at both sites and throughout all FY with a wider gender gap in 2020. There were no significant differences in retention in PrEP between FY.
Anticipated improvements in linkage, engagement, and retention in PrEP in 2020 at the MVAHCS and DC VAMC may not have been seen due to the COVID-19 pandemic. Furthermore, engagement rates in PrEP remained low overall, particularly among Black Veterans and cisgender women. Novel PrEP delivery models are needed to engage these populations in PrEP following the COVID-19 pandemic. Interactive dashboards and tele-PrEP may have played a big role in sustained retention in PrEP at the VHA.
Literatur
3.
Zurück zum Zitat Nunn AS, Brinkley-Rubinstein L, Oldenburg CE, Mayer KH, Mimiaga M, Patel R, et al. Defining the HIV pre-exposure prophylaxis care continuum. Volume 31. AIDS. Lippincott Williams and Wilkins; 2017. pp. 731–4. Nunn AS, Brinkley-Rubinstein L, Oldenburg CE, Mayer KH, Mimiaga M, Patel R, et al. Defining the HIV pre-exposure prophylaxis care continuum. Volume 31. AIDS. Lippincott Williams and Wilkins; 2017. pp. 731–4.
4.
Zurück zum Zitat Robles G, Hong C, Yu M, Starks TJ. Intersecting Communities and PrEP Uptake among US-based latinx sexual minority men. J Racial Ethn Health Disparities. 2021. Robles G, Hong C, Yu M, Starks TJ. Intersecting Communities and PrEP Uptake among US-based latinx sexual minority men. J Racial Ethn Health Disparities. 2021.
5.
Zurück zum Zitat Buffel V, Reyniers T, Masquillier C, Thunissen E, Nöstlinger C, Laga M, et al. Awareness of, willingness to take PrEP and its actual use among belgian MSM at high risk of HIV infection: secondary analysis of the belgian european MSM Internet Survey. AIDS Behav. 2022;26(6):1793–807.CrossRefPubMed Buffel V, Reyniers T, Masquillier C, Thunissen E, Nöstlinger C, Laga M, et al. Awareness of, willingness to take PrEP and its actual use among belgian MSM at high risk of HIV infection: secondary analysis of the belgian european MSM Internet Survey. AIDS Behav. 2022;26(6):1793–807.CrossRefPubMed
6.
Zurück zum Zitat Marcus JL, Hurley LB, Hare CB, Nguyen DP, Phengrasamy T, Silverberg MJ et al. Preexposure Prophylaxis for HIV Prevention in a large Integrated Health Care System: Adherence, Renal Safety, and Discontinuation. Marcus JL, Hurley LB, Hare CB, Nguyen DP, Phengrasamy T, Silverberg MJ et al. Preexposure Prophylaxis for HIV Prevention in a large Integrated Health Care System: Adherence, Renal Safety, and Discontinuation.
7.
Zurück zum Zitat van Epps P, Maier M, Lund B, Bryant Howren M, Beck B, Beste L et al. Medication Adherence in a Nationwide Cohort of Veterans Initiating Pre-exposure Prophylaxis (PrEP) to Prevent HIV Infection [Internet]. 2017. Available from: www.jaids.com. van Epps P, Maier M, Lund B, Bryant Howren M, Beck B, Beste L et al. Medication Adherence in a Nationwide Cohort of Veterans Initiating Pre-exposure Prophylaxis (PrEP) to Prevent HIV Infection [Internet]. 2017. Available from: www.​jaids.​com.
8.
Zurück zum Zitat Gillespie D, Couzens Z, de Bruin M, Hughes DA, Jones A, Ma R et al. PrEP use, sexual Behaviour, and PrEP Adherence among Men who have sex with men living in Wales Prior to and during the COVID-19 pandemic. AIDS Behav. 2022. Gillespie D, Couzens Z, de Bruin M, Hughes DA, Jones A, Ma R et al. PrEP use, sexual Behaviour, and PrEP Adherence among Men who have sex with men living in Wales Prior to and during the COVID-19 pandemic. AIDS Behav. 2022.
9.
Zurück zum Zitat Chow EPF, Hocking JS, Ong JJ, Schmidt T, Buchanan A, Rodriguez E et al. Changing the use of HIV preexposure prophylaxis among men who have sex with men during the COVID-19 Pandemic in Melbourne, Australia. Open Forum Infect Dis. 2020;7(7). Chow EPF, Hocking JS, Ong JJ, Schmidt T, Buchanan A, Rodriguez E et al. Changing the use of HIV preexposure prophylaxis among men who have sex with men during the COVID-19 Pandemic in Melbourne, Australia. Open Forum Infect Dis. 2020;7(7).
10.
Zurück zum Zitat Stephenson R, Chavanduka TMD, Rosso MT, Sullivan SP, Pitter RA, Hunter AS, et al. Sex in the Time of COVID-19: results of an online survey of Gay, bisexual and other men who have sex with men’s experience of sex and HIV Prevention during the US COVID-19 Epidemic. AIDS Behav. 2021;25(1):40–8.CrossRefPubMed Stephenson R, Chavanduka TMD, Rosso MT, Sullivan SP, Pitter RA, Hunter AS, et al. Sex in the Time of COVID-19: results of an online survey of Gay, bisexual and other men who have sex with men’s experience of sex and HIV Prevention during the US COVID-19 Epidemic. AIDS Behav. 2021;25(1):40–8.CrossRefPubMed
11.
Zurück zum Zitat Hong C, Horvath KJ, Stephenson R, Nelson KM, Petroll AE, Walsh JL, et al. PrEP use and persistence among young sexual minority men 17–24 Years Old during the COVID-19 pandemic. AIDS Behav. 2022;26(3):631–8.CrossRefPubMed Hong C, Horvath KJ, Stephenson R, Nelson KM, Petroll AE, Walsh JL, et al. PrEP use and persistence among young sexual minority men 17–24 Years Old during the COVID-19 pandemic. AIDS Behav. 2022;26(3):631–8.CrossRefPubMed
12.
Zurück zum Zitat Pampati S, Emrick K, Siegler AJ, Jones J. Changes in Sexual Behavior, PrEP Adherence, and Access to Sexual Health Services Because of the COVID-19 Pandemic among a Cohort of PrEP-Using MSM in the South. J Acquir Immune Defic Syndr (1988). 2021;87(1):639–43. Pampati S, Emrick K, Siegler AJ, Jones J. Changes in Sexual Behavior, PrEP Adherence, and Access to Sexual Health Services Because of the COVID-19 Pandemic among a Cohort of PrEP-Using MSM in the South. J Acquir Immune Defic Syndr (1988). 2021;87(1):639–43.
13.
Zurück zum Zitat Satcher Johnson A, Gant Z, Huang Y, lin, Smith D, Li J, Hu X et al. Core indicators for monitoring the Ending the HIV Epidemic initiative (preliminary data): National HIV Surveillance System data reported through June 2021; and preexposure prophylaxis (PrEP) data reported through March 2021 [Internet]. Vol. 2. 2021. Available from: http://wwwn.cdc.gov/dcs/ContactUs/Form. Satcher Johnson A, Gant Z, Huang Y, lin, Smith D, Li J, Hu X et al. Core indicators for monitoring the Ending the HIV Epidemic initiative (preliminary data): National HIV Surveillance System data reported through June 2021; and preexposure prophylaxis (PrEP) data reported through March 2021 [Internet]. Vol. 2. 2021. Available from: http://​wwwn.​cdc.​gov/​dcs/​ContactUs/​Form.
14.
Zurück zum Zitat Huang YLA, Zhu W, Wiener J, Kourtis AP, Hall HI, Hoover KW. Impact of Coronavirus Disease 2019 (COVID-19) on human immunodeficiency virus (HIV) pre-exposure Prophylaxis Prescriptions in the United States-A Time-Series Analysis. Clin Infect Dis. 2022;75(1):e1020–7.CrossRefPubMed Huang YLA, Zhu W, Wiener J, Kourtis AP, Hall HI, Hoover KW. Impact of Coronavirus Disease 2019 (COVID-19) on human immunodeficiency virus (HIV) pre-exposure Prophylaxis Prescriptions in the United States-A Time-Series Analysis. Clin Infect Dis. 2022;75(1):e1020–7.CrossRefPubMed
15.
Zurück zum Zitat Quan H, Sundararajan V, Halfon P, Fong A, Burnand B, Luthi JC et al. Coding Algorithms for Defining Comorbidities in ICD-9-CM and ICD-10 Administrative Data. 2005. Quan H, Sundararajan V, Halfon P, Fong A, Burnand B, Luthi JC et al. Coding Algorithms for Defining Comorbidities in ICD-9-CM and ICD-10 Administrative Data. 2005.
16.
Zurück zum Zitat CDC. US Public Health Service: PREEXPOSURE PROPHYLAXIS FOR THE PREVENTION OF HIV INFECTION IN THE UNITED STATES. – 2021 UPDATE, A CLINICAL PRACTICE GUIDELINE. 2021. CDC. US Public Health Service: PREEXPOSURE PROPHYLAXIS FOR THE PREVENTION OF HIV INFECTION IN THE UNITED STATES. – 2021 UPDATE, A CLINICAL PRACTICE GUIDELINE. 2021.
17.
Zurück zum Zitat Jasuja GK, De Groot A, Quinn EK, Ameli O, Hughto JMW, Dunbar M, et al. Beyond gender identity disorder Diagnoses Codes: an examination of additional methods to identify Transgender individuals in administrative databases. Med Care. 2020;58(10):903–11.CrossRefPubMedPubMedCentral Jasuja GK, De Groot A, Quinn EK, Ameli O, Hughto JMW, Dunbar M, et al. Beyond gender identity disorder Diagnoses Codes: an examination of additional methods to identify Transgender individuals in administrative databases. Med Care. 2020;58(10):903–11.CrossRefPubMedPubMedCentral
18.
Zurück zum Zitat Office of Public and Intergovernmental Affairs. VA health records now display gender identity. 2022. Office of Public and Intergovernmental Affairs. VA health records now display gender identity. 2022.
19.
Zurück zum Zitat Gregg E, Linn C, Nace E, Gelberg L, Cowan B, Fulcher JA. Implementation of HIV Preexposure Prophylaxis in a homeless primary care setting at the Veterans Affairs. J Prim Care Community Health. 2020;11:2150132720908370.CrossRefPubMedPubMedCentral Gregg E, Linn C, Nace E, Gelberg L, Cowan B, Fulcher JA. Implementation of HIV Preexposure Prophylaxis in a homeless primary care setting at the Veterans Affairs. J Prim Care Community Health. 2020;11:2150132720908370.CrossRefPubMedPubMedCentral
20.
Zurück zum Zitat Allison KHM, David Malebranche A. Barriers to the Wider Use of Pre-exposure Prophylaxis in the United States: A Narrative Review. Available from: https://doi.org/10.6084/. Allison KHM, David Malebranche A. Barriers to the Wider Use of Pre-exposure Prophylaxis in the United States: A Narrative Review. Available from: https://​doi.​org/​10.​6084/​.​
21.
Zurück zum Zitat Breaux K, Ashong C, Steinberg T, Park Y. Implementation of preventive care in a large urban Veterans Affairs HIV clinic. JAAPA. 2022;35(12):1.CrossRefPubMed Breaux K, Ashong C, Steinberg T, Park Y. Implementation of preventive care in a large urban Veterans Affairs HIV clinic. JAAPA. 2022;35(12):1.CrossRefPubMed
22.
Zurück zum Zitat Hoth AB, Shafer C, Dillon DB, Mayer R, Walton G, Ohl ME. Iowa TelePrEP: a public-health-partnered Telehealth Model for Human Immunodeficiency Virus Preexposure Prophylaxis Delivery in a rural state. Sex Transm Dis. 2019;46(8):507–12.CrossRefPubMed Hoth AB, Shafer C, Dillon DB, Mayer R, Walton G, Ohl ME. Iowa TelePrEP: a public-health-partnered Telehealth Model for Human Immunodeficiency Virus Preexposure Prophylaxis Delivery in a rural state. Sex Transm Dis. 2019;46(8):507–12.CrossRefPubMed
23.
Zurück zum Zitat Rowan SE, Patel RR, Schneider JA, Smith DK. Same-day prescribing of daily oral pre-exposure prophylaxis for HIV prevention. Lancet HIV. 2021;8(2):e114–20.CrossRefPubMed Rowan SE, Patel RR, Schneider JA, Smith DK. Same-day prescribing of daily oral pre-exposure prophylaxis for HIV prevention. Lancet HIV. 2021;8(2):e114–20.CrossRefPubMed
24.
26.
Zurück zum Zitat Beste LA, Keddem S, Borgerding J, Lowy E, Gardella C, McFarland L et al. Sexually transmitted infection testing in the national Veterans Health Administration patient cohort during the COVID-19 pandemic. Open Forum Infect Dis. 2022. Beste LA, Keddem S, Borgerding J, Lowy E, Gardella C, McFarland L et al. Sexually transmitted infection testing in the national Veterans Health Administration patient cohort during the COVID-19 pandemic. Open Forum Infect Dis. 2022.
Metadaten
Titel
Impact of the COVID-19 Pandemic on the PrEP Cascade at Two Veterans Affairs Healthcare Systems
verfasst von
Omar Harfouch
Emily Comstock
Roman Kaplan
Debra Benator
Heather Rivasplata
Eleanor Wilson
Publikationsdatum
05.08.2023
Verlag
Springer US
Erschienen in
AIDS and Behavior / Ausgabe 4/2024
Print ISSN: 1090-7165
Elektronische ISSN: 1573-3254
DOI
https://doi.org/10.1007/s10461-023-04146-5

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