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10.01.2019 | Meningokokken | Leitthema

Impfstoffe gegen Meningokokken für das Kindesalter

verfasst von: Prof. Dr. T. Tenenbaum, W. Hellenbrand, H. Schroten

Erschienen in: Monatsschrift Kinderheilkunde | Ausgabe 3/2019

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Zusammenfassung

Derzeit wird von der Ständigen Impfkommission (STIKO) am Robert Koch-Institut die Verabreichung der Impfstoffe gegen Meningokokken der Serogruppen A, B, W und Y nur für Risikogruppen, die Impfung gegen Meningokokken der Serogruppe C hingegen für alle Kinder im ersten Lebensjahr empfohlen. Zwei rekombinant hergestellte proteinbasierte Meningokokken-B-Impfstoffe, der Vierkomponenten-Meningokokken-B-Impfstoff 4CMenB und ein Zweikomponentenimpfstoff mit 2 Faktor-H-Bindungsprotein(fHbp)-Varianten (rLP2086), sind in Deutschland ebenso zugelassen. Die Abdeckung der in Deutschland zirkulierenden Stämme durch diese Impfstoffe beträgt ungefähr 80 %. Der 4CMenB-Impfstoff kann in allen Altersstufen eingesetzt werden, der fHbp-Impfstoff ist nur für Adoleszente und Erwachsene zugelassen. Die mögliche universelle Implementation von MenB-Impfstoffen bei Kindern wird von der STIKO bezüglich der Epidemiologie sowie den Langzeitdaten zu Impfstoffwirksamkeit, Verträglichkeit und Effekten auf das Trägertum weiter evaluiert.

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Titel: Impfstoffe gegen Meningokokken für das Kindesalter
verfasst von: Prof. Dr. T. Tenenbaum
W. Hellenbrand
H. Schroten
Publikationsdatum: 10.01.2019
Verlag: Springer Medizin
Schlagwörter: Meningokokken
Impfungen
Erschienen in: Monatsschrift Kinderheilkunde / Ausgabe 3/2019
Print ISSN: 0026-9298
Elektronische ISSN: 1433-0474
DOI: https://doi.org/10.1007/s00112-018-0635-7

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