Skip to main content
Erschienen in: Supportive Care in Cancer 7/2010

01.07.2010 | Original Article

Implementation of a pharmacist-initiated pharmaceutical handover for oncology and haematology patients being transferred to critical care units

verfasst von: John Coutsouvelis, Carmela E. Corallo, Michael J. Dooley, Josephine Foo, Ann Whitfield

Erschienen in: Supportive Care in Cancer | Ausgabe 7/2010

Einloggen, um Zugang zu erhalten

Abstract

Goals of work

An information gap with respect to specific therapies was identified when patients were transferred from the oncology and haematology unit (OHU) to the critical care units. The goal was to implement and evaluate the effectiveness of a pharmacist-initiated pharmaceutical handover (PIPH) for patients being transferred from the OHU to the critical care units at a major teaching hospital.

Patients and methods

A PIPH process for the specific therapies of mouthcare, chemotherapy regimen, growth factors and antibiotics was developed. The PIPH was delivered in written format or combined written and verbal format. The impact of the PIPH was by assessment of recorded clinical pharmacist interventions. Data were analysed to evaluate any difference in the number of interventions relating to and the time to administration of the specific therapies.

Main results

Data were available for 30 patient transfers in the pre-implementation group, with 22 transfers available in the post-implementation period. The number of interventions relating to the specific therapies was significantly reduced in the post-implementation group (144 vs 26; p < 0.0001). A significantly greater proportion of the specific therapies were administered on time in the post-implementation group (57% vs 96%; p < 0.0001).

Conclusions

Clinical pharmacists in the specialty area of oncology and haematology can improve the continuum of care when their patients are transferred to other units. By providing an accurate handover about specific therapies, there is an overall improvement in the prescribing and timely administration of these therapies.
Literatur
1.
Zurück zum Zitat Bond CA, Raehl CL (2008) 2006 national clinical pharmacy services survey: clinical pharmacy services, collaborative drug management, medication errors and pharmacy technology. Phramacotherapy 28:1–13CrossRef Bond CA, Raehl CL (2008) 2006 national clinical pharmacy services survey: clinical pharmacy services, collaborative drug management, medication errors and pharmacy technology. Phramacotherapy 28:1–13CrossRef
2.
Zurück zum Zitat Bond CA, Raehl CL (2007) Clinical pharmacy services, pharmacy staffing, and hospital mortality rates. Pharmacotherapy 27:481–493CrossRefPubMed Bond CA, Raehl CL (2007) Clinical pharmacy services, pharmacy staffing, and hospital mortality rates. Pharmacotherapy 27:481–493CrossRefPubMed
3.
Zurück zum Zitat Dooley MJ, Allen KM, Doecke CJ, Galbraith KJ, Taylor GR, Bright J et al (2004) A prospective multicentre study on pharmacist initiated changes to drug therapy and patient management in acute care government funded hospitals. Br J Clin Pharmacol 57:512–521CrossRef Dooley MJ, Allen KM, Doecke CJ, Galbraith KJ, Taylor GR, Bright J et al (2004) A prospective multicentre study on pharmacist initiated changes to drug therapy and patient management in acute care government funded hospitals. Br J Clin Pharmacol 57:512–521CrossRef
4.
Zurück zum Zitat Kaboli PJ, Hoth AB, McClinnon BJ, Schipper JL (2006) Clinical pharmacists and inpatient medical care: a systematic review. Arch Intern Med 1666:955–964CrossRef Kaboli PJ, Hoth AB, McClinnon BJ, Schipper JL (2006) Clinical pharmacists and inpatient medical care: a systematic review. Arch Intern Med 1666:955–964CrossRef
5.
Zurück zum Zitat Royal S, Smeaton L, Avery AJ, Humitz B, Sheikh A (2006) Interventions in primary care to reduce medication related adverse events and hospital admissions: systematic review and meta-analysis. Qual Saf Health Care 15:23–31CrossRefPubMed Royal S, Smeaton L, Avery AJ, Humitz B, Sheikh A (2006) Interventions in primary care to reduce medication related adverse events and hospital admissions: systematic review and meta-analysis. Qual Saf Health Care 15:23–31CrossRefPubMed
6.
Zurück zum Zitat Schiffer CA (2003) Differences in outcome in adolescents with acute lymphoblastic leukaemia: a consequence of better regimens? Better doctors? Both? J Clin Oncol 21:760–761CrossRefPubMed Schiffer CA (2003) Differences in outcome in adolescents with acute lymphoblastic leukaemia: a consequence of better regimens? Better doctors? Both? J Clin Oncol 21:760–761CrossRefPubMed
7.
Zurück zum Zitat Skeel RT (2003) Handbook of cancer chemotherapy, 6th edn. Lippincott Williams & Wilkins, Philadelphia Skeel RT (2003) Handbook of cancer chemotherapy, 6th edn. Lippincott Williams & Wilkins, Philadelphia
8.
Zurück zum Zitat Caggiano V, Weiss RV, Rickert TS, Linde-Zwirble WT (2005) Incidence, cost, and mortality of neutropenia hospitilization associated with chemotherapy. Cancer 103:1916–1924CrossRefPubMed Caggiano V, Weiss RV, Rickert TS, Linde-Zwirble WT (2005) Incidence, cost, and mortality of neutropenia hospitilization associated with chemotherapy. Cancer 103:1916–1924CrossRefPubMed
9.
Zurück zum Zitat Dekker A, Bulley S, Beyene J, Dupuis LL, Doyle JJ, Sung L (2006) Meta-analysis of randomized controlled trials of prophylactic granulocyte colony-stimulating factor and granulocyte-macrophage colony-stimulating factor after autologous and allogenic stem cell transplantation. J Clin Oncol 24:5207–5215CrossRefPubMed Dekker A, Bulley S, Beyene J, Dupuis LL, Doyle JJ, Sung L (2006) Meta-analysis of randomized controlled trials of prophylactic granulocyte colony-stimulating factor and granulocyte-macrophage colony-stimulating factor after autologous and allogenic stem cell transplantation. J Clin Oncol 24:5207–5215CrossRefPubMed
10.
Zurück zum Zitat Smith TJ, Khatcheressian J, Lyman GH, Ozer H, Armitage JO, Balducci L et al (2006) 2006 update of recommendations for the use of white blood cell growth factors: an evidence-based clinical practical guideline. J Clin Oncol 24:3187–3205CrossRefPubMed Smith TJ, Khatcheressian J, Lyman GH, Ozer H, Armitage JO, Balducci L et al (2006) 2006 update of recommendations for the use of white blood cell growth factors: an evidence-based clinical practical guideline. J Clin Oncol 24:3187–3205CrossRefPubMed
11.
Zurück zum Zitat Kumar A, Roberts D, Wood KE, Light B, Parrillo JE, Sharma S et al (2006) Duration of hypotension before initiation of effective antimicrobial therapy is the critical determinant of survival in human septic shock. Crit Care Med 34:1589–1596CrossRefPubMed Kumar A, Roberts D, Wood KE, Light B, Parrillo JE, Sharma S et al (2006) Duration of hypotension before initiation of effective antimicrobial therapy is the critical determinant of survival in human septic shock. Crit Care Med 34:1589–1596CrossRefPubMed
14.
Zurück zum Zitat Bergmann OJ, Mogensen SC, Ellermann-Eriksen S, Ellegaard J (1997) Acyclovir prophylaxis and fever during remission-induction therapy of patients with acute myeloid leukemia: a randomized, double-blind, placebo-controlled trial. J Clin Oncol 15:2269–2274PubMed Bergmann OJ, Mogensen SC, Ellermann-Eriksen S, Ellegaard J (1997) Acyclovir prophylaxis and fever during remission-induction therapy of patients with acute myeloid leukemia: a randomized, double-blind, placebo-controlled trial. J Clin Oncol 15:2269–2274PubMed
13.
Zurück zum Zitat Cullen MH, Billingham LJ, Gaunt CH, Steven NM (2007) Rational selection of patients for antibacterial prophylaxis after chemotherapy. J Clin Oncol 25:4821–4828CrossRefPubMed Cullen MH, Billingham LJ, Gaunt CH, Steven NM (2007) Rational selection of patients for antibacterial prophylaxis after chemotherapy. J Clin Oncol 25:4821–4828CrossRefPubMed
15.
Zurück zum Zitat Robenshtok E, Gafter-Gvili A, Goldberg E, Weinberger M, Yeshurum M, Leibovici L et al (2007) Antifungal prophylaxis in cancer patients after chemotherapy or hematopoietic stem-cell transplantation: systematic review and meta-analysis. J Clin Oncol 25:5471–5489CrossRefPubMed Robenshtok E, Gafter-Gvili A, Goldberg E, Weinberger M, Yeshurum M, Leibovici L et al (2007) Antifungal prophylaxis in cancer patients after chemotherapy or hematopoietic stem-cell transplantation: systematic review and meta-analysis. J Clin Oncol 25:5471–5489CrossRefPubMed
16.
Zurück zum Zitat Bellm LA, Epstein JB, Rose-Ped A, Martin P, Fuchs HJ (2000) Patient reports of complications of bone marrow transplantation. Support Care Cancer 8:33–39PubMed Bellm LA, Epstein JB, Rose-Ped A, Martin P, Fuchs HJ (2000) Patient reports of complications of bone marrow transplantation. Support Care Cancer 8:33–39PubMed
17.
Zurück zum Zitat Sonis ST, Oster G, Fuchs H, Bellm L, Bradford WZ, Eldelsberg J et al (2001) Oral mucositis and the clinical and economic outcomes of hematopoietic stem-cell transplantation. J Clin Oncol 19:2201–2205PubMed Sonis ST, Oster G, Fuchs H, Bellm L, Bradford WZ, Eldelsberg J et al (2001) Oral mucositis and the clinical and economic outcomes of hematopoietic stem-cell transplantation. J Clin Oncol 19:2201–2205PubMed
19.
Zurück zum Zitat The Society of Hospital Pharmacists of Australia Committee of Specialty Practice in Critical Care (2002) SHPA standards of practice for critical care pharmacy practice. J Pharm Pract Res 32:115–118 The Society of Hospital Pharmacists of Australia Committee of Specialty Practice in Critical Care (2002) SHPA standards of practice for critical care pharmacy practice. J Pharm Pract Res 32:115–118
20.
Zurück zum Zitat The Society of Hospital Pharmacists of Australia Committee of Specialty Practice in Oncology (2008) SHPA standards of practice for the provision of clinical oncology pharmacy services. J Pharm Pract Res 38:58–60 The Society of Hospital Pharmacists of Australia Committee of Specialty Practice in Oncology (2008) SHPA standards of practice for the provision of clinical oncology pharmacy services. J Pharm Pract Res 38:58–60
21.
Zurück zum Zitat Bonaventura A (1995) Complications of cytotoxic therapy—Part 2. Aust Prescr 18:105–107 Bonaventura A (1995) Complications of cytotoxic therapy—Part 2. Aust Prescr 18:105–107
22.
Zurück zum Zitat Mughal TI, Goldman JM, Mughal ST (2006) Understanding leukemias, lymphomas and myelomas, 1st edn. Taylor and Francis, UK Mughal TI, Goldman JM, Mughal ST (2006) Understanding leukemias, lymphomas and myelomas, 1st edn. Taylor and Francis, UK
23.
Zurück zum Zitat Shanholtz C (2001) Acute life-threatening toxicity of cancer treatment. Crit Care Clin 17:483–502CrossRefPubMed Shanholtz C (2001) Acute life-threatening toxicity of cancer treatment. Crit Care Clin 17:483–502CrossRefPubMed
24.
Zurück zum Zitat Bourget S, Allenet B, Bedouch P, Bosson JL, Calpo J (2007) Physicians' expectations towards pharmacy services on the ward. J Pharm Belg 62:130–134PubMed Bourget S, Allenet B, Bedouch P, Bosson JL, Calpo J (2007) Physicians' expectations towards pharmacy services on the ward. J Pharm Belg 62:130–134PubMed
25.
Zurück zum Zitat Liekweg A, Westfeld M, Jaehde U (2004) From oncology pharmacy to pharmaceutical care: new contributions to multidisciplinary cancer care. Support Care Cancer 12:73–79CrossRefPubMed Liekweg A, Westfeld M, Jaehde U (2004) From oncology pharmacy to pharmaceutical care: new contributions to multidisciplinary cancer care. Support Care Cancer 12:73–79CrossRefPubMed
26.
Zurück zum Zitat Price SO, Newnham MA (1994) Physician perceptions of clinical pharmacy encounters in a family practice clinic. Top Hosp Pharm Manage 14:13–20PubMed Price SO, Newnham MA (1994) Physician perceptions of clinical pharmacy encounters in a family practice clinic. Top Hosp Pharm Manage 14:13–20PubMed
27.
Zurück zum Zitat Schwartzberg E, Rubinovich S, Hassin D, Haspel J, Ben-Moshe A, Oren M et al (2006) Developing and implementing a model for changing physicians' prescribing habits—the role of clinical pharmacy in leading the change. J Clin Pharm Ther 31:179–185CrossRefPubMed Schwartzberg E, Rubinovich S, Hassin D, Haspel J, Ben-Moshe A, Oren M et al (2006) Developing and implementing a model for changing physicians' prescribing habits—the role of clinical pharmacy in leading the change. J Clin Pharm Ther 31:179–185CrossRefPubMed
28.
Zurück zum Zitat Shirley CV, Mutnick AH, Daniel WL, Volles D (2006) Evaluation of a pharmacy clinical practice model by other healthcare professionals. Proceedings from ASHP Midyear Clinical Meeting, vol 41. American Society of Health-System Pharmacists, Bathesda Shirley CV, Mutnick AH, Daniel WL, Volles D (2006) Evaluation of a pharmacy clinical practice model by other healthcare professionals. Proceedings from ASHP Midyear Clinical Meeting, vol 41. American Society of Health-System Pharmacists, Bathesda
30.
Zurück zum Zitat Millar JA, Silla RC, Lee GE, Berwick A (2008) The national inpatient medication chart: critical audit of design and performance at a tertiary hospital. Med J Aust 188:95–99PubMed Millar JA, Silla RC, Lee GE, Berwick A (2008) The national inpatient medication chart: critical audit of design and performance at a tertiary hospital. Med J Aust 188:95–99PubMed
Metadaten
Titel
Implementation of a pharmacist-initiated pharmaceutical handover for oncology and haematology patients being transferred to critical care units
verfasst von
John Coutsouvelis
Carmela E. Corallo
Michael J. Dooley
Josephine Foo
Ann Whitfield
Publikationsdatum
01.07.2010
Verlag
Springer-Verlag
Erschienen in
Supportive Care in Cancer / Ausgabe 7/2010
Print ISSN: 0941-4355
Elektronische ISSN: 1433-7339
DOI
https://doi.org/10.1007/s00520-009-0713-4

Weitere Artikel der Ausgabe 7/2010

Supportive Care in Cancer 7/2010 Zur Ausgabe

Update Onkologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.