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Erschienen in:

12.07.2016 | The Global Epidemic (S.H. Vermund, Section Editor)

Implementing Community Engagement for Combination Prevention: Lessons Learnt From the First Year of the HPTN 071 (PopART) Community-Randomized Study

verfasst von: Musonda Simwinga, Virginia Bond, Nozizwe Makola, Graeme Hoddinott, Steve Belemu, Rhonda White, Kwame Shanaube, Janet Seeley, Ayana Moore, on behalf of the HPTN 071 (PopART) study team

Erschienen in: Current HIV/AIDS Reports | Ausgabe 4/2016

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Abstract

Key to the success of a HIV combination prevention strategy, including galvanizing the current push to roll out universal test and treat (UTT), is the involvement and buy-in of the populations that the strategy aims to reach. Drawing on the experiences of engaging with 21 communities in Zambia and South Africa in the design and implementation of a community-randomized study of combination HIV prevention including UTT, this paper reflects on the commitment to, approaches for and benefits of involving communities. Key lessons learnt include that all communities require continuous community engagement (CE) and engagement needs to be adapted to diverse local contexts. Intrinsic goals of CE, such as building trusting relationships between study stakeholders, are necessary precursors to instrumental goals which strengthen the research quality. Engaging the community for combination prevention requires that CE successfully bridges science and real life, paying attention to influences in the wider social landscape.

1.•

MacQueen K, Bhan A, Frohlich J, Holzer J, Sugarman J. Evaluating community engagement in global health research: the need for metrics. BMC Med Ethics. 2015;16(1):1–9. This article reviews and described guidelines on CE. It draws and distinguishes perspectives of CE from normative guidelines (by national and international bodies), scholarly work (literature) and practical guidelines in the field. The article points to a lack of consensus regarding CE approaches, goals and indicators to measure its contribution in the context of health research.CrossRef

2.••

Tindana P, de Vries J, Campbell M, Littler K, Seeley J, Marshall P, et al. Community engagement strategies for genomic studies in Africa: a review of the literature. BMC Med Ethics. 2015;16:24. This review article identifies ‘effective’ CE strategies necessary for the successful implementation of genomic studies in Africa. Challenges in identifying CE strategies included the lack of uniformity in the definition of key concepts such as community, and the lack of systematic evaluation of CE approaches. In addition, the choice of CE strategies depends on the goal of CE for the study.CrossRefPubMedPubMedCentral

Skidmore D. The ideology of community care. London: Chapman & Hall; 1994.

Black A, Hughes P. The identification and analysis of indicators of community strength and outcomes. Department of Family and Community Services. 2001. https://www.dss.gov.au/about-the-department/publications-articles/research-publications/occasional-paper-series/number-3-the-identification-and-analysis-of-indicators-of-community-strength-and-outcomes. Accessed 10 March 2016.

5.••

Kilifi. Consent and community engagement in diverse research contexts reviewing and developing research and practice. J Empir Res Hum Res Ethics. 2013;8(4):1–18. The article reports on a CE and consent workshop held in Kilifi. Kenya, in 2011. Participants were from different parts of the World and were involved in research and practice of CE and consent. The distinction between institutional wide and study specific CE (and hybrid of the two) was highlighted. The workshop critically reviewed processes for conducting CE and consent in research.CrossRef

Cori A, Ayles H, Beyers N, Schaap A, Floyd S, Sabapathy K, et al. HPTN 071 (PopART): a cluster-randomized trial of the population impact of an HIV combination prevention intervention including universal testing and treatment: mathematical model. PLoS ONE. 2014;9(1), e84511.CrossRefPubMedPubMedCentral

Hayes R, Ayles H, Beyers N, Sabapathy K, Floyd S, Shanaube K, et al. HPTN 071 (PopART): rationale and design of a cluster-randomised trial of the population impact of an HIV combination prevention intervention including universal testing and treatment—a study protocol for a cluster randomised trial. Trials. 2014;15:57.CrossRefPubMedPubMedCentral

Ayles H, Muyoyeta M, Du Toit E, Schaap A, Floyd S, Simwinga M, et al. Effect of household and community interventions on the burden of tuberculosis in southern Africa: the ZAMSTAR community-randomised trial. Lancet. 2013;382(9899):1183–94.CrossRefPubMed

Helen A, Charalambos S, Nulda B, Richard H, Godfrey-Faussett P. ZAMSTAR, the Zambia South Africa TB and HIV reduction study: design of a 2 × 2 factorial community randomized trial. Trials. 2008;9(1):63.CrossRef

10.••

Angwenyi V, Kamuya D, Mwachiro D, Kalama B, Marsh V, Njuguna P, et al. Complex realities: community engagement for a paediatric randomized controlled malaria vaccine trial in Kilifi, Kenya. Trials. 2014;15:65. The article documents CE processes in practice in a paediatric randomised controlled malaria vaccine trial in Kilifi, Kenya. CE was mainly focused on early research activity. Consultations that precede research activities and systematic consultation with leaders and knowledgeable individuals were found to be beneficial. The article highlights the critical link between two interrelated purposes of CE; information sharing and relationship building.CrossRefPubMedPubMedCentral

11.

Emanuel EJ, Wendler D, Grady C. WHat makes clinical research ethical? JAMA. 2000;283(20):2701–11.CrossRefPubMed

12.

Dickert N, Sugarman J. Ethical goals of community consultation in research. Am J Public Health. 2005;95(7):1123–7.CrossRefPubMedPubMedCentral

13.

UNAIDS, AVAC. Good participatory practice, guidelines for biomedical HIV prevention trials, in UNAIDS/07.30E/ JC1364E2007: 2007.

14.

Tindana P, Singh JA, Tracy SC, Upshur RE, Daar AS, Singer PA, et al. Grand challenges in global health: community engagement in research in developing countries. PLoS Med. 2007;4(9):e273.CrossRefPubMedPubMedCentral

15.

Kendall C. The role of formal qualitative research in negotiating community acceptance: the case of dengue control in El Progreso, Honduras. Hum Organ. 1998;57(2):217–21.CrossRef

16.

Cox LE, Rouff JR, Svendsen KH, Markowitz M, Abrams DI. Community advisory boards: their role in AIDS clinical trials. Health Soc Work. 1998;23(4):290–7.CrossRefPubMed

17.

Reddy P, Buchanan D, Sifunda S, James S, Naidoo N. The role of community advisory boards in health research: divergent views in the South African experience. SAHARA. 2011; 7(3).

18.

Mwinga A, Moodley K. Engaging with Community Advisory Boards (CABs) in Lusaka Zambia: perspectives from the research team and CAB members. BMC Med Ethics. 2015;16(1):1–11.CrossRef

19.

Ntshanga SP, Ngcobo PS, Mabaso ML. Establishment of a Community Advisory Board (CAB) for tuberculosis control and research in the Inanda, Ntuzuma and KwaMashu (INK) area of KwaZulu-Natal, South Africa. Health Policy. 2010;95:211–5.CrossRefPubMed

20.

Morin SF, Morfit S, Maiorana A, Aramrattana A, Goicochea P, Mutsambi JM, et al. Building community partnerships: case studies of community advisory boards at research sites in Peru, Zimbabwe, and Thailand. Clin Trials. 2008;5(2):147–56.CrossRefPubMed

21.

Nakibinge S, Maher D, Katende J, Kamali A, Grosskurth H, Seeley J, et al. Community engagement in health research: two decades of experience from a research project on HIV in rural Uganda. Trop Med Int Health. 2009;14(9):6.

22.

Tindana PO, Rozmovits L, Boulanger RF, Bandewar SV, Aborigo RA, Hodgson AV, et al. Aligning community engagement with traditional authority structures in global health research: a case study from northern Ghana. Am J Public Health. 2011;101(10):1857–67.CrossRefPubMedPubMedCentral

23.

Simwinga M, Kabero C. Community engagement. In: Krugger M, Ndebele P, Horn L, editors. Research ethics in Africa: a resource for research ethics committees. South Africa: Sun Press; 2014.

24.

Mack N, Kirkendale S, Omullo P, Odhiambo J, Ratlhagana M, Masaki M, et al. Implementing good participatory practice guidelines in the FEM-PrEP Preexposure Prophylaxis Trial for HIV Prevention among African Women: a focus on local stakeholder involvement. 2013.

25.

Becker AB, Israel BA, Gustat J, Reyes AG, Allen III A. Strategies and techniques for effective group process in CBPR partnerships. In: Israel BA, Eng E, Schulz AJ, Parker EA, editors. Methods for community-based participatory research for health. San Francisco: Jossey-Bass; 2013.

26.

Morin SF, Maiorana A, Koester KA, Sheon NM, Richards TA. Community consultation in HIV prevention research: a study of community advisory boards at 6 research sites. AIDS J Acquir Immune Defic Syndr. 2003;33:513–20.CrossRefPubMed

27.

Sieber JE. Introduction: points to consider in community-engaged research. J Empir Res Hum Res Ethics. 2010;5(1):3–4.CrossRefPubMed

28.

Sieber JE. Life is short, ethics is long. J Empir Res Hum Res Ethics. 2010;5(4):1–2.CrossRef

29.

Geissler PW, Pool R. Editorial: popular concerns about medical research projects in sub-Saharan Africa—a critical voice in debates about medical research ethics. Tropical Med Int Health. 2006;11(7):975–82.CrossRef

30.

Geissler WP. Kachinja are coming! Encounters around medical research work in a Kenyan Village. Africa. 2005; 75(2).

Titel: Implementing Community Engagement for Combination Prevention: Lessons Learnt From the First Year of the HPTN 071 (PopART) Community-Randomized Study
verfasst von: Musonda Simwinga
Virginia Bond
Nozizwe Makola
Graeme Hoddinott
Steve Belemu
Rhonda White
Kwame Shanaube
Janet Seeley
Ayana Moore
on behalf of the HPTN 071 (PopART) study team
Publikationsdatum: 12.07.2016
Verlag: Springer US
Erschienen in: Current HIV/AIDS Reports / Ausgabe 4/2016
Print ISSN: 1548-3568
Elektronische ISSN: 1548-3576
DOI: https://doi.org/10.1007/s11904-016-0322-z

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Implementing Community Engagement for Combination Prevention: Lessons Learnt From the First Year of the HPTN 071 (PopART) Community-Randomized Study

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Parodontalbehandlung verbessert Prognose bei Katheterablation

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