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Erschienen in: Journal of Cancer Research and Clinical Oncology 6/2008

01.06.2008 | Original Paper

Improved characterisation of solitary solid pancreatic tumours using contrast enhanced transabdominal ultrasound

verfasst von: C. F. Dietrich, B. Braden, M. Hocke, M. Ott, A. Ignee

Erschienen in: Journal of Cancer Research and Clinical Oncology | Ausgabe 6/2008

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Abstract

Background

Contrast enhanced ultrasound (CEUS) is a new imaging method for detection and characterisation of liver tumours. The role of CEUS in pancreatic disease is less obvious. We prospectively evaluated CEUS for characterization of undetermined solid pancreatic lesions (gold standard histology).

Patients and methods

A total of 112 solitary undetermined pancreatic masses (70 ductal adenocarcinoma and 42 neoplastic nodules of other origin) were prospectively examined in patients without metastatic disease using transabdominal ultrasound. Tumour enhancing features were analyzed in comparison to the surrounding pancreatic parenchyma in patients with adequate visualisation.

Results

The sign of iso-hypervascularity as a sign of non-ductal adenocarcinoma showed a sensitivity of 100%, specifity of 90% and accuracy of 93.8%. The sign of hypovascularity as a sign of ductal adenocarcinoma showed a sensitivity of 90%, specifity of 100% and an accuracy of 93.8%.

Conclusion

CEUS allows differential diagnosis of ductal adenocarcinoma and non-ductal adenocarcinoma (mainly neuroendocrine tumours and (microcystic) serous pancreatic adenoma) in the most of cases.
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Metadaten
Titel
Improved characterisation of solitary solid pancreatic tumours using contrast enhanced transabdominal ultrasound
verfasst von
C. F. Dietrich
B. Braden
M. Hocke
M. Ott
A. Ignee
Publikationsdatum
01.06.2008
Verlag
Springer-Verlag
Erschienen in
Journal of Cancer Research and Clinical Oncology / Ausgabe 6/2008
Print ISSN: 0171-5216
Elektronische ISSN: 1432-1335
DOI
https://doi.org/10.1007/s00432-007-0326-6

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