Effect of bariatric surgery on health-related quality of life (HRQOL) varies greatly. This might be caused by the diversity in questionnaires used to assess HRQOL and the weight loss of the studied population. This study assesses the relationship between weight loss and HRQOL in primary Roux-en-Y gastric bypass (RYGB) patients by using an obesity-specific (impact of weight on quality of life-lite, IWQOL-lite) and a generic (RAND-36) questionnaire.
HRQOL and weight parameters were assessed before and 15 and 24 months after RYGB surgery. HRQOL was assessed by using IWQOL-lite (an obesity-specific questionnaire consisting of one total score and five domains) and RAND-36 (a generic questionnaire consisting of two subtotal scores, the physical health summary (PHS) and mental health summary (MHS), and nine scales).
Two thousand one hundred thirty-seven patients were included. HRQOL improved significantly after RYGB. Preoperative BMI was negatively related to baseline PHS (p < 0.001) and IWQOL-lite total (p < 0.001). Percentage total weight loss (%TWL) was positively related to HRQOL score at both follow-up moments. Change in HRQOL from baseline to 24 months was related to %TWL at 24 months in both subtotals of RAND-36 and IWQOL-lite total score (p ≤ 0.001 in all).
HRQOL improves after RYGB. Higher %TWL is related to greater improvement in HRQOL and better HRQOL 15 and 24 months after RYGB. The variance in the effect of RYGB surgery on HRQOL can be explained by the questionnaire used and weight loss of the population.
Fayers P, Hays R. Assessing quality of life in clinical trails. New York: Oxford Press; 2005.
Stunkard AJ, Wadden TA. Psychological aspects of severe obesity. Am J Clin Nutr. 1992;55(2 Suppl):524S–32S. PubMed
van der Zee KI, Sanderman R, Heyink JW. Psychometric qualities of the RAND 36-item health survey 1.0: a multidimensional measure of general health status. International Journal of Behavioral Medicine. 1996;3(2):104. CrossRef
Karlsson J, Taft C, Ryden A. Ten-year trends in health-related quality of life after surgical and conventional treatment for severe obesity: the SOS intervention study. Int J Obes. 2007;31(8):1248–61. CrossRef
Karen I. van der Zee, Robbert Sanderman. Het meten van de algemene gezondheidstoestand met de RAND-36: een handleiding; 2012.
- Improvement of Health-Related Quality of Life After Roux-en-Y Gastric Bypass Related to Weight Loss
Valerie M. Monpellier
Evangelia E. Antoniou
Edo O. Aarts
Ignace M. C. Janssen
Anita T. M. Jansen
- Springer US
Neu im Fachgebiet Chirurgie
e.Med Kampagnen-Visual, Mail Icon II