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Obesity Surgery
Erschienen in: Obesity Surgery 10/2021

06.08.2021 | Original Contributions

Improvement of Renal Function After Bariatric Surgery: a Systematic Review and Meta-analysis

verfasst von: Hongyan Huang, Jun Lu, Xiaojiang Dai, Zhixin Li, Liyong Zhu, Shaihong Zhu, Liangping Wu

Erschienen in: Obesity Surgery | Ausgabe 10/2021

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Abstract

Background/Objective

The effect of bariatric surgery in renal function varies and the postoperative benefit time point remains unclear. We aim to assess the changes of renal function after bariatric surgery (BS) in different postoperative periods and subgroups.

Methods

We searched the databases of PubMed and Cochrane from inception to December 14, 2020. Articles included in the study were drawn from all recipients of BS that provided assessments of renal function pre and post-surgery. Meta-analysis was performed to compare glomerular filtration rate (GFR), serum creatinine, albumin-to-creatinine ratio (ACR), and albuminuria before and after BS.

Results

The study included 49 articles involving 8515 patients. Compared with pre-operative renal function, the overall analysis showed that bariatric surgery significantly reduced serum creatinine levels, ACR, and albuminuria. There was significant increase of GFR in the CKD subgroup, yet a noticeable decrease in the hyperfiltration subgroup. The most significant improvement in GFR was seen 6–12 months after BS, while ACR dropped most dramatically 12–24 months after BS.

Conclusions

Bariatric surgery can improve renal function in obese patients with kidney dysfunction, especially 1 year after surgery.

Graphical abstract

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Metadaten
Titel
Improvement of Renal Function After Bariatric Surgery: a Systematic Review and Meta-analysis
verfasst von
Hongyan Huang
Jun Lu
Xiaojiang Dai
Zhixin Li
Liyong Zhu
Shaihong Zhu
Liangping Wu
Publikationsdatum
06.08.2021
Verlag
Springer US
Erschienen in
Obesity Surgery / Ausgabe 10/2021
Print ISSN: 0960-8923
Elektronische ISSN: 1708-0428
DOI
https://doi.org/10.1007/s11695-021-05630-4

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