Skip to main content
Erschienen in: Internal and Emergency Medicine 1/2019

12.06.2018 | EM - ORIGINAL

In situ simulation in the management of anaphylaxis in a pediatric emergency department

verfasst von: Simona Barni, Francesca Mori, Mattia Giovannini, Marco de Luca, Elio Novembre

Erschienen in: Internal and Emergency Medicine | Ausgabe 1/2019

Einloggen, um Zugang zu erhalten

Abstract

Anaphylaxis is a potentially life-threatening, rapid-onset hypersensitive reaction, usually treated in the emergency department (ED). Failure to recognize anaphylaxis leads to under-treatment with epinephrine and even when correctly diagnosed, epinephrine is not always administered. In addition, often patients who are treated in the ED are not referred for allergy work-up. Simulation is a tool that increases exposure to events in a safe environment, allowing trainers to develop skills without harming patients. The main purpose of our study was to determine whether in situ simulation training increases the frequency of epinephrine use. The secondary aim was to observe whether simulation modifies the number of children investigated over the years before and after the setting up of the simulation training. All patients with anaphylaxis referred to the Pediatric Emergency Department (PED) of the Anna Meyer Children’s Hospital from 2004 to 2010 [pre-simulation (PRE-s) period], and from 2011 to 2016 [post-simulation (POST-s) period], were retrospectively included in this observational study. Simulation was carried out using a high-fidelity patient simulator mannequin (SimBaby, Laerdal Medical, Inc, Stavanger, NY). The diagnosis of anaphylaxis was based on the EAACI guidelines. The use of epinephrine significantly increased (p < 0.05) between the PRE-s and POST-s time periods: 2.4% versus 10% patients, respectively. During the two time periods, we also observed a significant increase (p = 0.011) in the number of patients who underwent a complete allergy work-up: 36% versus 51% patients, respectively. According to our results, the in situ simulation program improved the correct management of anaphylaxis in terms of prompt use of epinephrine, and it also led to a higher number of patients being referred to the allergy unit for evaluation.
Literatur
1.
Zurück zum Zitat Bohlke K, Davis RL, DeStefano F et al (2004) Epidemiology of anaphylaxis among children and adolescents en- rolled in a health maintenance organization. J Allergy Clin Immunol 113(3):536–542CrossRefPubMed Bohlke K, Davis RL, DeStefano F et al (2004) Epidemiology of anaphylaxis among children and adolescents en- rolled in a health maintenance organization. J Allergy Clin Immunol 113(3):536–542CrossRefPubMed
2.
Zurück zum Zitat Grabenhenrich LB, Dölle S, Moneret-Vautrin A et al (2016) Anaphylaxis in children and adolescents: the European anaphylaxis registry. J Allergy Clin Immunol 137(4):1128–1137CrossRefPubMed Grabenhenrich LB, Dölle S, Moneret-Vautrin A et al (2016) Anaphylaxis in children and adolescents: the European anaphylaxis registry. J Allergy Clin Immunol 137(4):1128–1137CrossRefPubMed
3.
Zurück zum Zitat Motosue MS, Bellolio MF, Van Houten HK, Shah ND, Campbell RL (2017) Increasing emergency department visits for anaphylaxis, 2005–2014. J Allergy Clin Immunol Pract 5(1):171–175CrossRefPubMed Motosue MS, Bellolio MF, Van Houten HK, Shah ND, Campbell RL (2017) Increasing emergency department visits for anaphylaxis, 2005–2014. J Allergy Clin Immunol Pract 5(1):171–175CrossRefPubMed
4.
Zurück zum Zitat Mullins RJ, Wainstein BK, Barnes EH et al (2016) Increases in anaphylaxis fatalities in Australia 1997–2013. Clin Exp Allergy 46(8):1099–1110CrossRefPubMed Mullins RJ, Wainstein BK, Barnes EH et al (2016) Increases in anaphylaxis fatalities in Australia 1997–2013. Clin Exp Allergy 46(8):1099–1110CrossRefPubMed
5.
Zurück zum Zitat Boyce JA, Assa’ad A, Burks AW et al (2010) NIAID- sponsored expert panel. guidelines for the diagnosis and management of food allergy in the United States: report of the NIAID-sponsored expert panel. J Allergy Clin Immunol 126(6 Suppl):S1–S58PubMedPubMedCentral Boyce JA, Assa’ad A, Burks AW et al (2010) NIAID- sponsored expert panel. guidelines for the diagnosis and management of food allergy in the United States: report of the NIAID-sponsored expert panel. J Allergy Clin Immunol 126(6 Suppl):S1–S58PubMedPubMedCentral
6.
Zurück zum Zitat World Health Organization (2011) The selection and use of essential medicines. World Health Org Tech Rep Ser 965:1–249 World Health Organization (2011) The selection and use of essential medicines. World Health Org Tech Rep Ser 965:1–249
7.
Zurück zum Zitat Ross MP, Ferguson M, Street D et al (2008) Analysis of food-allergic and anaphylactic events in the national electronic injury surveillance system. J Allergy Clin Immunol 121:166–171CrossRefPubMed Ross MP, Ferguson M, Street D et al (2008) Analysis of food-allergic and anaphylactic events in the national electronic injury surveillance system. J Allergy Clin Immunol 121:166–171CrossRefPubMed
8.
Zurück zum Zitat Campbell RL, Hagan JB, Manivannan V et al (2012) Evaluation of national institute of allergy and infection disease/food allergy & anaphylaxis Network criteria for the diagnosis of anaphylaxis in emergency department patients. J Allergy Clin Immunol 129:748–752 ((IIb)) CrossRefPubMed Campbell RL, Hagan JB, Manivannan V et al (2012) Evaluation of national institute of allergy and infection disease/food allergy & anaphylaxis Network criteria for the diagnosis of anaphylaxis in emergency department patients. J Allergy Clin Immunol 129:748–752 ((IIb)) CrossRefPubMed
9.
Zurück zum Zitat Clark S, Long AA, Gaeta TJ, Camargo CA (2005) Multicenter study of emergency department visits for insect sting allergies. J Allergy Clin Immunol 116:643–649 ((IIb)) CrossRefPubMed Clark S, Long AA, Gaeta TJ, Camargo CA (2005) Multicenter study of emergency department visits for insect sting allergies. J Allergy Clin Immunol 116:643–649 ((IIb)) CrossRefPubMed
10.
Zurück zum Zitat Mehl A, Wahn U, Niggemann B (2005) Anaphylactic reactions in children—a questionnaire-based survey in Germany. Allergy 60:1440–1445CrossRefPubMed Mehl A, Wahn U, Niggemann B (2005) Anaphylactic reactions in children—a questionnaire-based survey in Germany. Allergy 60:1440–1445CrossRefPubMed
11.
Zurück zum Zitat Campbell RL, Luke A, Weaver AL et al (2008) Prescriptions for self-injectable epinephrine and follow-up referral in emergency department patients presenting with anaphylaxis. Ann Allergy Asthma Immunol 101:631–636CrossRefPubMedPubMedCentral Campbell RL, Luke A, Weaver AL et al (2008) Prescriptions for self-injectable epinephrine and follow-up referral in emergency department patients presenting with anaphylaxis. Ann Allergy Asthma Immunol 101:631–636CrossRefPubMedPubMedCentral
12.
Zurück zum Zitat Bock SA, Munoz-Furlong A, Sampson HA (2007) Further fatalities caused by anaphylactic reactions to food, 2001–2006. J Allergy Clin Immunol 119(4):1016–1018CrossRefPubMed Bock SA, Munoz-Furlong A, Sampson HA (2007) Further fatalities caused by anaphylactic reactions to food, 2001–2006. J Allergy Clin Immunol 119(4):1016–1018CrossRefPubMed
13.
Zurück zum Zitat Huang F, Chawla K, Järvinen KM, Nowak-Wegrzyn A (2012) Anaphylaxis in a New York city pediatric emergency department: triggers, treatments, and outcomes. J Allergy Clin Immunol 129:162–168CrossRefPubMed Huang F, Chawla K, Järvinen KM, Nowak-Wegrzyn A (2012) Anaphylaxis in a New York city pediatric emergency department: triggers, treatments, and outcomes. J Allergy Clin Immunol 129:162–168CrossRefPubMed
14.
Zurück zum Zitat Bradley P (2006) The history of simulation in medical education and possible future directions. Med Educ 40:254–262CrossRefPubMed Bradley P (2006) The history of simulation in medical education and possible future directions. Med Educ 40:254–262CrossRefPubMed
16.
Zurück zum Zitat Brockow K, Schallmayer S, Beyer K et al (2015) Effects of a structured educational intervention on knowledge and emergency management in patients at risk for anaphylaxis. Allergy 70:227–235CrossRefPubMed Brockow K, Schallmayer S, Beyer K et al (2015) Effects of a structured educational intervention on knowledge and emergency management in patients at risk for anaphylaxis. Allergy 70:227–235CrossRefPubMed
17.
Zurück zum Zitat Kennedy JL, Jones SM, Porter N et al (2013) High-fidelity hybrid simulation of allergic emergencies demonstrates improved preparedness for office emergencies in pediatric allergy clinics. J Allergy Clin Immunol Pract 1(6):608–617CrossRefPubMed Kennedy JL, Jones SM, Porter N et al (2013) High-fidelity hybrid simulation of allergic emergencies demonstrates improved preparedness for office emergencies in pediatric allergy clinics. J Allergy Clin Immunol Pract 1(6):608–617CrossRefPubMed
18.
Zurück zum Zitat Shelton R (2009) The emergency severity index 5-level triage system. Dimens Crit Care Nurs 28:9–12CrossRefPubMed Shelton R (2009) The emergency severity index 5-level triage system. Dimens Crit Care Nurs 28:9–12CrossRefPubMed
19.
Zurück zum Zitat Muraro A, Roberts G, Worm M et al (2014) Anaphylaxis: guidelines from the European academy of allergy and clinical immunology. Allergy 69(8):1026–1045CrossRefPubMed Muraro A, Roberts G, Worm M et al (2014) Anaphylaxis: guidelines from the European academy of allergy and clinical immunology. Allergy 69(8):1026–1045CrossRefPubMed
20.
Zurück zum Zitat Weinstock PH, Kappus LJ, Garden A, Burns JP (2009) Simulation at the point of care: reduced-cost, in situ training via a mobile cart. Pediatr Crit Care Med 10:176–181CrossRefPubMed Weinstock PH, Kappus LJ, Garden A, Burns JP (2009) Simulation at the point of care: reduced-cost, in situ training via a mobile cart. Pediatr Crit Care Med 10:176–181CrossRefPubMed
21.
Zurück zum Zitat Rudolph JW, Simon R, Dufresne RL, Raemer DB (2006) There’s no such thing as ‘‘nonjudgmental’’ debriefing: a theory and method for debriefing with good judgment. Simul Healthc 1:49–55 (Spring) CrossRefPubMed Rudolph JW, Simon R, Dufresne RL, Raemer DB (2006) There’s no such thing as ‘‘nonjudgmental’’ debriefing: a theory and method for debriefing with good judgment. Simul Healthc 1:49–55 (Spring) CrossRefPubMed
22.
Zurück zum Zitat Alvarez-Perea A, Ameiro B, Morales C, Zambrano G, Rodríguez A, Guzmán M, Zubeldia JM, Baeza ML (2017) Anaphylaxis in the pediatric emergency department: analysis of 133 cases after an allergy workup. J Allergy Clin Immunol Pract 5:1256–1263CrossRefPubMed Alvarez-Perea A, Ameiro B, Morales C, Zambrano G, Rodríguez A, Guzmán M, Zubeldia JM, Baeza ML (2017) Anaphylaxis in the pediatric emergency department: analysis of 133 cases after an allergy workup. J Allergy Clin Immunol Pract 5:1256–1263CrossRefPubMed
23.
Zurück zum Zitat Ben-Shoshan M, La Vieille S, Eisman H, Alizadehfar R, Mill C, Perkins E et al (2013) Anaphylaxis treated in a Canadian pediatric hospital: incidence, clinical characteristics, triggers, and management. J Allergy Clin Immunol 132:739–741CrossRefPubMed Ben-Shoshan M, La Vieille S, Eisman H, Alizadehfar R, Mill C, Perkins E et al (2013) Anaphylaxis treated in a Canadian pediatric hospital: incidence, clinical characteristics, triggers, and management. J Allergy Clin Immunol 132:739–741CrossRefPubMed
24.
Zurück zum Zitat Simons FE, Ebisawa M, Sanchez-Borges M et al (2015) 2015 update of the evidence base: world allergy organization anaphylaxis guidelines. World Allergy Organ J 8(1):32CrossRefPubMedPubMedCentral Simons FE, Ebisawa M, Sanchez-Borges M et al (2015) 2015 update of the evidence base: world allergy organization anaphylaxis guidelines. World Allergy Organ J 8(1):32CrossRefPubMedPubMedCentral
25.
Zurück zum Zitat Worm M, Eckermann O, Dolle S et al (2014) Triggers and treatment of anaphylaxis: an analysis of 4,000 cases from Germany, Austria and Switzerland. Dtsch Arztebl Int 111(21):367–375 (24) PubMedPubMedCentral Worm M, Eckermann O, Dolle S et al (2014) Triggers and treatment of anaphylaxis: an analysis of 4,000 cases from Germany, Austria and Switzerland. Dtsch Arztebl Int 111(21):367–375 (24) PubMedPubMedCentral
26.
Zurück zum Zitat Russell WS, Farrar JR, Nowak R et al (2013) Evaluating the management of anaphylaxis in US emergency departments: guidelines vs. practice. World J Emerg Med 4(2):98–106CrossRefPubMedPubMedCentral Russell WS, Farrar JR, Nowak R et al (2013) Evaluating the management of anaphylaxis in US emergency departments: guidelines vs. practice. World J Emerg Med 4(2):98–106CrossRefPubMedPubMedCentral
27.
Zurück zum Zitat Simons KJ, Simons FE (2010) Epinephrine and its use in anaphylaxis: current issues. Curr Opin Allergy Clin Immunol 10(4):354–361CrossRefPubMed Simons KJ, Simons FE (2010) Epinephrine and its use in anaphylaxis: current issues. Curr Opin Allergy Clin Immunol 10(4):354–361CrossRefPubMed
28.
Zurück zum Zitat Sheikh A, Ten Broek V, Brown SG, Simons FE (2007) H1-antihistamines for the treatment of anaphylaxis: cochrane systematic review. Allergy 62(8):830–837CrossRefPubMed Sheikh A, Ten Broek V, Brown SG, Simons FE (2007) H1-antihistamines for the treatment of anaphylaxis: cochrane systematic review. Allergy 62(8):830–837CrossRefPubMed
29.
Zurück zum Zitat Choo KJ, Simons E, Sheikh A (2010) Glucocorticoids for the treatment of anaphylaxis: cochrane systematic review. Allergy 65(10):1205–1211CrossRefPubMed Choo KJ, Simons E, Sheikh A (2010) Glucocorticoids for the treatment of anaphylaxis: cochrane systematic review. Allergy 65(10):1205–1211CrossRefPubMed
30.
Zurück zum Zitat Hernandez L, Papalia S, Pujalte G (2016) Anaphylaxis. Prim Care Clin Office Pract 43:477–485CrossRef Hernandez L, Papalia S, Pujalte G (2016) Anaphylaxis. Prim Care Clin Office Pract 43:477–485CrossRef
31.
Zurück zum Zitat Beyer K, Eckermann O, Hompes S, Grabenhenrich L, Worm M (2012) Anaphylaxis in an emergency setting—elicitors, therapy and incidence of severe allergic reactions. Allergy 11:1451–1456 (67) CrossRef Beyer K, Eckermann O, Hompes S, Grabenhenrich L, Worm M (2012) Anaphylaxis in an emergency setting—elicitors, therapy and incidence of severe allergic reactions. Allergy 11:1451–1456 (67) CrossRef
32.
Zurück zum Zitat Alvarez-Perea A, Tomás-Pérez M, Martínez-Lezcano P et al (2015) Anaphylaxis in adolescent/adult patients treated in the emergency department: differences between initial impressions and the definitive diagnosis. J Investig Allergol Clin Immunol 25:288–294PubMed Alvarez-Perea A, Tomás-Pérez M, Martínez-Lezcano P et al (2015) Anaphylaxis in adolescent/adult patients treated in the emergency department: differences between initial impressions and the definitive diagnosis. J Investig Allergol Clin Immunol 25:288–294PubMed
33.
Zurück zum Zitat Campbell RL, Park MA, Kueber MA, Lee S, Hagan JB (2015) Outcomes of allergy/immunology follow-up after an emergency department evaluation for anaphy- laxis. J Allergy Clin Immunol Pract 3:88–93CrossRefPubMed Campbell RL, Park MA, Kueber MA, Lee S, Hagan JB (2015) Outcomes of allergy/immunology follow-up after an emergency department evaluation for anaphy- laxis. J Allergy Clin Immunol Pract 3:88–93CrossRefPubMed
34.
Zurück zum Zitat Patterson MD, Geis GL, Falcone RA, LeMaster T, Wears RL (2013) In situ simulation: detection of safety threats and teamwork training in a high risk emergency department. BMJ Qual Saf 22(6):468–477CrossRefPubMed Patterson MD, Geis GL, Falcone RA, LeMaster T, Wears RL (2013) In situ simulation: detection of safety threats and teamwork training in a high risk emergency department. BMJ Qual Saf 22(6):468–477CrossRefPubMed
35.
Zurück zum Zitat Brazil V (2017) Translational simulation: not ‘where?’ But ‘why?’ a functional view of in situ simulation. Adv Simul 2:20CrossRef Brazil V (2017) Translational simulation: not ‘where?’ But ‘why?’ a functional view of in situ simulation. Adv Simul 2:20CrossRef
Metadaten
Titel
In situ simulation in the management of anaphylaxis in a pediatric emergency department
verfasst von
Simona Barni
Francesca Mori
Mattia Giovannini
Marco de Luca
Elio Novembre
Publikationsdatum
12.06.2018
Verlag
Springer International Publishing
Erschienen in
Internal and Emergency Medicine / Ausgabe 1/2019
Print ISSN: 1828-0447
Elektronische ISSN: 1970-9366
DOI
https://doi.org/10.1007/s11739-018-1891-1

Weitere Artikel der Ausgabe 1/2019

Internal and Emergency Medicine 1/2019 Zur Ausgabe

Leitlinien kompakt für die Innere Medizin

Mit medbee Pocketcards sicher entscheiden.

Seit 2022 gehört die medbee GmbH zum Springer Medizin Verlag

Update Innere Medizin

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.