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Erschienen in: Magnetic Resonance Materials in Physics, Biology and Medicine 1/2018

18.09.2017 | Research Article

In vitro evaluation of flow patterns and turbulent kinetic energy in trans-catheter aortic valve prostheses

verfasst von: Daniel Giese, Kilian Weiss, Bettina Baeßler, Navid Madershahian, Yeong-Hoon Choi, David Maintz, Alexander C. Bunck

Erschienen in: Magnetic Resonance Materials in Physics, Biology and Medicine | Ausgabe 1/2018

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Abstract

Objectives

The objective of the current work was to evaluate flow and turbulent kinetic energy in different transcatheter aortic valve implants using highly undersampled time-resolved multi-point 3-directional phase-contrast measurements (4D Flow MRI) in an in vitro setup.

Materials and methods

A pulsatile flow setup was used with a compliant tubing mimicking a stiff left ventricular outflow tract and ascending aorta. Five different implants were measured using a highly undersampled multi-point 4D Flow MRI sequence. Velocities and turbulent kinetic energy values were analysed and compared.

Results

Strong variations of turbulent kinetic energy distributions between the valves were observed. Maximum turbulent kinetic energy values ranged from 100 to over 500 J/m3 while through-plane velocities were similar between all valves.

Conclusion

Highly accelerated 4D Flow MRI for the measurement of velocities and turbulent kinetic energy values allowed for the assessment of hemodynamic parameters in five different implant models. The presented setup, measurement protocol and analysis methods provides an efficient approach to compare different valve implants and could aid future novel valve designs.
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Metadaten
Titel
In vitro evaluation of flow patterns and turbulent kinetic energy in trans-catheter aortic valve prostheses
verfasst von
Daniel Giese
Kilian Weiss
Bettina Baeßler
Navid Madershahian
Yeong-Hoon Choi
David Maintz
Alexander C. Bunck
Publikationsdatum
18.09.2017
Verlag
Springer Berlin Heidelberg
Erschienen in
Magnetic Resonance Materials in Physics, Biology and Medicine / Ausgabe 1/2018
Print ISSN: 0968-5243
Elektronische ISSN: 1352-8661
DOI
https://doi.org/10.1007/s10334-017-0651-y

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