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Erschienen in: Supportive Care in Cancer 4/2019

02.02.2019 | Review Article

Incidence and severity of sexual dysfunction among women with breast cancer: a meta-analysis based on female sexual function index

verfasst von: Liwei Jing, Chao Zhang, Wei Li, Feng Jin, Aiping Wang

Erschienen in: Supportive Care in Cancer | Ausgabe 4/2019

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Abstract

Purpose

Previous meta-analyses have examined the prevalence of sexual dysfunction among women with cancer, but there is no breast cancer (BC)-specific study. We therefore conducted a meta-analysis to examine the prevalence and severity of female sexual dysfunction (FSD) in women with BC.

Methods

We searched PubMed, Embase, Cochrane Library, CNKI, WanFang Data, and VIP for relevant studies published between April 2000 and January 2017. Data were extracted from studies which assessed FSD prevalence and sexual function in women with BC using the female sexual function index (FSFI). Meta-analyses were performed by pooling the prevalence rates of FSD and total FSFI scores. Meta regression was performed to explore the sources of heterogeneity.

Results

We selected 19 published studies involving a total of 2684 women with BC. In this study population, overall FSD prevalence was 73.4% (95% confidence interval (CI) 64.0%, 82.8%), and the total FSFI score was 19.28 (95% CI 17.39, 21.16). Among Asian, American, and European women with BC, there were significant differences in FSD prevalence (P < 0.001), and there was marginally significant difference (P = 0.07) in sexual function between these groups. There was also a marginally significant difference between individuals from mainland China and from other countries in FSD prevalence (P = 0.06) and FSFI score (P = 0.07).

Conclusions

Overall, women with BC have high FSD prevalence and low sexual function. American women with BC have a higher average FSD prevalence and lower average sexual function than Asian women with BC. The FSD prevalence in women with BC in mainland China was slightly higher than in other countries.
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Metadaten
Titel
Incidence and severity of sexual dysfunction among women with breast cancer: a meta-analysis based on female sexual function index
verfasst von
Liwei Jing
Chao Zhang
Wei Li
Feng Jin
Aiping Wang
Publikationsdatum
02.02.2019
Verlag
Springer Berlin Heidelberg
Erschienen in
Supportive Care in Cancer / Ausgabe 4/2019
Print ISSN: 0941-4355
Elektronische ISSN: 1433-7339
DOI
https://doi.org/10.1007/s00520-019-04667-7

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