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Erschienen in: Journal of Bone and Mineral Metabolism 3/2018

03.06.2017 | Original Article

Indian girls have higher bone mineral content per unit of lean body than boys through puberty

verfasst von: Anuradha V. Khadilkar, Neha Sanwalka, M. Zulf Mughal, Shashi Chiplonkar, Vaman Khadilkar

Erschienen in: Journal of Bone and Mineral Metabolism | Ausgabe 3/2018

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Abstract

Our aim is to describe changes in the muscle−bone unit assessed as a ratio of bone mineral content (BMC) to lean body mass (LBM) through puberty at total body and various skeletal sites in Indian boys and girls. A cross-sectional study was conducted (888 children, 480 boys, aged 5–17 years) in Pune, India. Pubertal staging was assessed. BMC, LBM and fat percentage at the arms, legs, android, gynoid and total body (less the head) were assessed by dual energy X-ray absorptiometry. The amount of BMC per unit LBM (BMC/LBM) was computed. Changes in mean BMC/LBM at 5 Tanner (pubertal) stages after adjustment for age and fat percentage were calculated. In boys, adjusted BMC/LBM was significantly higher with successive Tanner stages [legs (TS-II vs TS-I), android (TS-III vs TS-II, TS-IV vs TS-III) and gynoid region (TS-III vs TS-II and TS-II vs TS-I) (p < 0.05)]. In girls, adjusted BMC/LBM was significantly higher with successive Tanner stages at total body, legs and gynoid (TS-III vs TS-II; TS-II vs TS-I; TS-V vs TS-IV), arms (TS-I to TS-V) and android regions (TS-V vs TS-IV) (p < 0.05). Boys had significantly higher adjusted BMC/LBM than girls at earlier Tanner stages (TS-I to TS-III), whereas girls had significantly higher adjusted BMC/LBM than boys at later Tanner stages (TS-IV, TS-V) (p < 0.05). Indian boys and girls showed higher total and regional body, and age- and fat percentage-adjusted BMC/LBM with successive pubertal stages. Girls had higher BMC/LBM than boys which may possibly act as a reservoir for later demands of pregnancy and lactation.
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Metadaten
Titel
Indian girls have higher bone mineral content per unit of lean body than boys through puberty
verfasst von
Anuradha V. Khadilkar
Neha Sanwalka
M. Zulf Mughal
Shashi Chiplonkar
Vaman Khadilkar
Publikationsdatum
03.06.2017
Verlag
Springer Japan
Erschienen in
Journal of Bone and Mineral Metabolism / Ausgabe 3/2018
Print ISSN: 0914-8779
Elektronische ISSN: 1435-5604
DOI
https://doi.org/10.1007/s00774-017-0843-6

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